Jenna van Draanen1, Carol S Aneshensel2. 1. Department of Community Health Sciences, University of California, Los Angeles, 650 Charles E Young Drive S, Los Angeles, CA 90095, USA. Electronic address: jvandraa@uw.edu. 2. Department of Community Health Sciences, University of California, Los Angeles, 650 Charles E Young Drive S, Los Angeles, CA 90095, USA.
Abstract
BACKGROUND: Children who are exposed to parental substance use disorder (SUD) have a higher risk of SUD themselves. This study examines the extent to which the association between parental and own SUD is conditional upon childhood trauma, socioeconomic status, and gender. METHODS: This study uses data from the Nashville Stress and Health Study with 1234 respondents ages 25-65 collected from 2011 to 2014, weighted be representative of the general population. The association between parental SUD and own SUD was estimated using Cox Proportional Hazard Models, controlling for covariates, and testing for interactions. RESULTS: Other things being equal, the risk of own SUD is more strongly associated with parental SUD in households with childhood traumas among men, but not women. Childhood trauma is not associated with own SUD in the absence of parental SUD among men. For men with parental SUD exposure, just one traumatic event is associated with a 38% increased risk of own SUD (HR=1.382, SE=.201, p < 0.05). For men, living with grandparents is associated with added SUD risk (HR=1.476, SE=.228, p < 0.05). For women, childhood trauma is not associated with own SUD, but parental SUD (HR=1.556, SE=.238, p < 0.01), and early onset mood or anxiety disorder (HR=1.682, SE=.316, p < 0.01) are. For both genders, those who are African American have lower risk of SUD than those who are White (HR=0.774, SE=.109, p < 0.05 for women; HR=0.672, SE=.079, p < 0.01 for men). CONCLUSIONS: Parental SUD is associated with a substantial increase in risk for own SUD, and this association differs by gender and early trauma.
BACKGROUND: Children who are exposed to parental substance use disorder (SUD) have a higher risk of SUD themselves. This study examines the extent to which the association between parental and own SUD is conditional upon childhood trauma, socioeconomic status, and gender. METHODS: This study uses data from the Nashville Stress and Health Study with 1234 respondents ages 25-65 collected from 2011 to 2014, weighted be representative of the general population. The association between parental SUD and own SUD was estimated using Cox Proportional Hazard Models, controlling for covariates, and testing for interactions. RESULTS: Other things being equal, the risk of own SUD is more strongly associated with parental SUD in households with childhood traumas among men, but not women. Childhood trauma is not associated with own SUD in the absence of parental SUD among men. For men with parental SUD exposure, just one traumatic event is associated with a 38% increased risk of own SUD (HR=1.382, SE=.201, p < 0.05). For men, living with grandparents is associated with added SUD risk (HR=1.476, SE=.228, p < 0.05). For women, childhood trauma is not associated with own SUD, but parental SUD (HR=1.556, SE=.238, p < 0.01), and early onset mood or anxiety disorder (HR=1.682, SE=.316, p < 0.01) are. For both genders, those who are African American have lower risk of SUD than those who are White (HR=0.774, SE=.109, p < 0.05 for women; HR=0.672, SE=.079, p < 0.01 for men). CONCLUSIONS: Parental SUD is associated with a substantial increase in risk for own SUD, and this association differs by gender and early trauma.
Authors: Jake M Najman; Alexandra Clavarino; Tara R McGee; William Bor; Gail M Williams; Mohammad R Hayatbakhsh Journal: J Adolesc Health Date: 2010-06 Impact factor: 5.012
Authors: Kara R Douglas; Grace Chan; Joel Gelernter; Albert J Arias; Raymond F Anton; Roger D Weiss; Kathleen Brady; James Poling; Lindsay Farrer; Henry R Kranzler Journal: Addict Behav Date: 2009-08-08 Impact factor: 3.913
Authors: Bridget F Grant; Tulshi D Saha; W June Ruan; Risë B Goldstein; S Patricia Chou; Jeesun Jung; Haitao Zhang; Sharon M Smith; Roger P Pickering; Boji Huang; Deborah S Hasin Journal: JAMA Psychiatry Date: 2016-01 Impact factor: 21.596