Literature DB >> 35333913

Predictors and outcomes of recognition of intellectual disability for adults during hospital admissions: A retrospective data linkage study in NSW, Australia.

Adrian Raymond Walker1, Julian Norman Trollor1, Tony Florio2, Preeyaporn Srasuebkul1.   

Abstract

Adults with intellectual disability have high health care needs. Despite frequent contact with health services, they often receive inadequate health care. One method to improve health care delivery is reasonable adjustments, that is, the adaptation of health care delivery such that barriers to participation are removed for the person with disability. A starting point for the provision of reasonable adjustments is recognition of intellectual disability during the health care contact. To determine rates and predictors of the recognition of intellectual disability during hospital admissions, and its impact on admission metrics, we examined a population of adults with intellectual disability identified from disability services datasets from New South Wales, Australia between 2005 and 2014. Recognition of intellectual disability was determined by the recording of an International Classification of Diseases 10th revision (ICD-10) diagnostic code for intellectual disability during a given hospital admission. We examined how recognition of intellectual disability related to length of hospital episodes. We found an overall low rate of recognition of intellectual disability (23.79%) across all hospital episodes, with the proportion of hospital episodes recognising intellectual disability decreasing from 2005-2015. Admissions for adults with complex health profiles (e.g., those with many comorbidities, those with Autism Spectrum Disorder, and those admitted for urgent treatment) were more likely to recognise intellectual disability, but admissions for adults with complexity in other domains (i.e., for those in custody, or those with drug and alcohol disorders) were less likely to recognise intellectual disability. Recognition of intellectual disability was associated with longer episodes of care, possibly indicating the greater provision of reasonable adjustments. To improve the recognition of intellectual disability for adults during health service contacts, we advocate for the implementation of targeted initiatives (such as a nationwide disability flag to be included in health service records) to improve the provision of reasonable adjustments.

Entities:  

Mesh:

Year:  2022        PMID: 35333913      PMCID: PMC8956190          DOI: 10.1371/journal.pone.0266051

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


Introduction

People with intellectual disability have high health needs that require frequent use of acute health care services such as emergency departments and hospitalisations [1, 2]. People with intellectual disability often experience poor quality of care and inefficiency of care in these settings [3, 4], which contribute to reattendance at emergency departments, and readmission within close proximity to discharge [5, 6]. Failures of acute care are part of a broader health gap experienced by people with intellectual disability, including substantially reduced life expectancy [7] and a very high proportion of deaths from potentially avoidable causes [8, 9]. In Australia, this health gap has been characterised as systematic neglect by the Australian Royal Commission into Violence, Abuse, Neglect and Exploitation of People with Disability [3]. Developing solutions to this problem is a matter of urgency for this population. One way to improve the experience of people with intellectual disability as they interact with the health care system is to ensure reasonable adjustments are made during health service contacts [10, 11]. Reasonable adjustments are defined as removing barriers to services that may affect people with disability, such as changing the way services are delivered, altering policies or procedures as appropriate, and providing staff with the proper training to meet the service needs of people with disability [10, 12], and are mandated during health service contacts in the United Kingdom for people with intellectual disability [13]. A recent metareview into reasonable adjustments in the health care system for people with intellectual disability suggested that changes like preadmission hospital visits, extended consultation times, and access to speciality intellectual disability nurses can substantially improve the quality of care received during an inpatient hospital episode by people with intellectual disability [10, 11, 14–16]. However, reasonable adjustments cannot be reliably employed within health service settings unless intellectual disability is identified. To improve the provision of reasonable adjustments, the United Kingdom’s National Health Service has recently introduced a nationwide “Reasonable Adjustments Flag” to indicate where patient may need reasonable adjustments during a service contact [17]. Such a flag assists identification of the disability, and triggers the need to ask about and document the adjustments required by the person during their contact with the health service. However, research suggests that intellectual disability is not consistently recognised during receipt of health and human services, and that recognition varies according to the sector with which the person has contact, creating an impediment to the uniform application of reasonable adjustments [11, 18–21]. Though previous research has examined factors that affect the recognition of intellectual disability in children [20], the factors that determine recognition of intellectual disability for adults during inpatient episodes (and therefore provision of reasonable adjustments) and the impact of this identification on the episode of care have not been identified. Using a data linkage population from New South Wales (NSW) Australia [22], we aimed to investigate what demographic and health factors affected the recognition of intellectual disability during contact with inpatient hospital services for adults. Furthermore, as no studies to date have leveraged large-linked datasets to examine how correctly identifying intellectual disability can affect the trajectory of an inpatient episode, we also aimed to investigate how the recognition of intellectual disability during an inpatient episode affected the length of that inpatient episode in our linked population. In doing so, we hoped to expand our understanding of the impacts of intellectual disability labelling during contacts with health services, and provide support for improved systems for recognising intellectual disability in health care systems worldwide.

Methods

Datasets, record linkage

This study was a retrospective cohort study, conducted as a substudy within a bigger data linkage infrastructure project described in Reppermund et al. [22]. All data used in this study were collected into administrative datasets during the interaction of members of the cohort with administrative services (e.g., hospital or disability services). No participant data were gained through direct interaction with members of the cohort, such as via structured interviews. Linkage was performed by the NSW Centre for Health Record Linkage using best practice methods. We used three datasets to define a population of adults known to have an intellectual disability within a disability related dataset: the New South Wales (NSW) disability services: the Disability Minimum Services Data Set (DS-MDS), which contains information on all people who received a disability service in NSW between 1 Jul 2005 to 30 Jun 2015; the NSW Public Guardian Data Set (PG), which contains information on all people who accessed Public Guardian services for decision-making assistance relating to health and lifestyle in NSW between 1 Jan 1994 and 30 Apr 2016; and the State-wide Disability Services Data Set (SDS), which contains information on those who received disability services while in custody between 1 Jan 2001 to 31 May 2016. We obtained information on hospital admissions from the Admitted Patients Data Collection (APDC), which records information about hospital episodes that occurred in NSW between 1 Jul 2001 to 30 Mar 2016, including a deidentified personal identifier, start and end dates and times, hospital location, principal diagnosis and up to 50 additional diagnoses, and some personal information such as a person’s sex, age, and current area of residence. Only hospital admissions that occurred after an individual had been identified in one or more of the disability datasets were included in this study. Information about whether an admission occurred during an episode of custody was also available to us through linkage to the Offender Integrated Management System (OIMS), and from which records were available for the study duration. We determined demographic data as per the linkage method described in Reppermund et al. [22].

Study population

The study population comprised of people with intellectual disability of ages 18 and over known to NSW disability services who appeared in the DS-MDS, PG, or SDS between 1 Jul 2005 and 30 Jun 2014, with their first appearance being the index date for the study (noting that this allowed some people to have an index date prior to the date they turned 18, as long as they turned 18 between 1 Jul 2005 and 30 Jun 2014). We excluded from the study population people with intellectual disability who did not have any hospital episodes after the index date in our study period. Persons younger than 18 years of age were excluded.

Follow up period

The follow up period for each person started from either their index date, the date of their first appearance in one of these datasets (if they were over 18), or the date they turned 18 (if they had appeared in one of these datasets at an earlier date), whichever occurred last. Their follow up ended at 30 Jun 2015 or their date of death, whichever occurred first.

Outcome variables

We measured our outcome variables at an episode of care level. The episode of care is the period of admitted patient care between a formal (cessation of a stay in hospital) or statistical (cessation of an episode occurring within a hospital stay, which may be followed by another episode) separation, characterised by only one care type [23-25]. That is, an episode of care can be thought of as a discrete contact with the hospital inpatient system where a person receives a particular type of care (e.g., mental health care, dialysis, rehabilitation, etc). We included all hospital episodes that occurred for an individual within the follow-up period when determining our outcome variables. Individuals were considered as having the first outcome variable, intellectual disability recognition, if intellectual disability was recorded in a hospital episode as a principal or additional diagnosis. We used the International Classification of Diseases 10th Edition (ICD-10) codes recorded for each hospital episode to identify the presence or absence of intellectual disability in a hospital episode (F7, F84.2, Q90, Q91, Q93, Q95-99. Q86, Q87, Q89.8, P04.3) [22]. The second outcome variable was the length of stay in days for a given hospital episode, obtained by the duration in days between episode start and end as recorded in the APDC. Episodes that started and finished within the same day were considered to have a length of stay one day. Episodes that were recorded as occurring within another episode (i.e., ‘nested’ episodes), were included as it could not be determined that these stays did not constitute discrete service contacts. A description of the steps taken to form the study population can be seen in Fig 1.
Fig 1

Description of the steps taken for study population formation.

Statistical analysis

We established the sociodemographic profile of the people who had valid episodes during the study period, the characteristics of valid episodes during the study period, and the raw proportion of hospital episodes where intellectual disability was recognised by financial year. All demographic information for this description was obtained using the linkage method described Reppermund et al. [22]. Intellectual disability recognition We conducted a multi-level logistic regression in Stata 17 to find predictors of intellectual disability recognition [26]. We used multi-level regression as people often present to hospital more than once in the study period. By including a random effect of person into our model, we assume that an individual’s hospital episodes will share some variance (i.e., we assume two episodes from one individual will be more similar than two episodes from two different individuals), allowing us to better control for the overall variance in the model. We tested this assumption with a likelihood-ratio test of fit against a standard logistic regression without a random effect of person. Fixed effects for the multi-level regression can be seen in Table 1. From the variables available in our datasets, we selected fixed effects for our models through a combination of expert medical knowledge about intellectual disability (JT), and internal discussion between the authors based on previous literature [9, 20, 27]. We included all variables selected in our analysis of intellectual disability recognition as fixed effects (besides intellectual disability recognition, which was the outcome variable for this model). Most fixed effects included were at the episode level (i.e., from data obtained directly from the records in that episode), with some variables (including age, Aboriginal and Torres Strait Islander Status, presence of Autism Spectrum Disorder) determined for each person based on the linkage method described in Reppermund et al. [22]. We used ICD-10 chapter 5 as the reference level for the principal diagnosis chapter variable as most ICD-10 codes for intellectual disability are in this chapter (and may include cases where the principal diagnosis was intellectual disability). We included a random effect of person identifier into the model. We did not include any ICD10 chapters where there were no records.
Table 1

Fixed effects included in multi-level regression modelling.

Fixed EffectTypeLevelDefinition
SexBinaryPersonSex of the individual as given by demographic data.
Financial yearCategoricalEpisodeFinancial year in which the episode occurred.
AgeContinuousEpisodeAge when the episode started.
Years after recognitionContinuousEpisodeYears since the individual was first recorded in the DS-MDS, PG, or SDS, calculated from the episode end date.
Local Health District locationCategoricalEpisodeLocal Health District in which an episode occurred, defined as per New South Wales Health categories (including St Vincent’s in the Specialty category) [28].
RemotenessCategoricalEpisodeAn individual’s remoteness category, as determined by Statistical Area 2 codes given by the Australian Bureau of Statistics [29]. In cases where one code contributed to multiple remoteness areas, the remoteness with the highest percentage was used.
Aboriginal or Torres Strait IslanderBinaryPersonWhether an individual was identified as Aboriginal or Torres Strait Islander as given by demographic data (output withheld for ethical reasons).
Index of relative socioeconomic disadvantage (IRSD) quintileCategorialEpisodeMeasure of disadvantage recorded during an episode, determined by Statistical Area 2 codes given by the Australian Bureau of Statistics [30].
In custody at time of episodeBinaryEpisodeWhether an episode occurred while the individual was in custody, determined by the OIMS dataset.
Drug and Alcohol episodeBinaryEpisodeWhether the episode had a record of drug or alcohol related ICD-10 diagnosis codes (either principal or additional diagnoses), using the definition from the Australian Institute of Health and Welfare [31].
Presence of Autism Spectrum DisorderBinaryPersonWhether an individual was recorded to have Autism Spectrum Disorder as given by demographic data.
Urgent admissionBinaryEpisodeWhether the episode had a flag indicating the individual required attention within 24 hours.
Summed Elix-Hauser comorbiditiesContinuousEpisodeNumber of Elix-Hauser comorbidity diagnoses recorded in an episode (either as principal or additional diagnoses) [32, 33].
Hospital typeCategoricalEpisodeWhether the episode was recorded as occurring in a public or private hospital.
Diagnosis chapterCategoricalEpisodeICD-10 diagnosis chapter to which the principal diagnosis for that episode belonged [34]. We used Chapter 5 Mental disorders as a reference group.
Intellectual disability recognition (length of stay model only)BinaryEpisodeWhether an episode had an ICD-10 code recognising intellectual disability.

DS-MDS = Disability Services Minimum Data Set; PG = Public Guardian; SDS = State-wide Disability Services Data Set; OIMS = Offender Integrated Management System; ICD-10 = International Classification of Diseases 10th edition

All variables are from the Admitted Patients Data Collection, unless otherwise specified.

DS-MDS = Disability Services Minimum Data Set; PG = Public Guardian; SDS = State-wide Disability Services Data Set; OIMS = Offender Integrated Management System; ICD-10 = International Classification of Diseases 10th edition All variables are from the Admitted Patients Data Collection, unless otherwise specified. We estimated the impact of effects in the model using the estimated likelihood, after fitting the regression model. The estimated likelihood represents the estimated average likelihood of intellectual disability recognition when a specific fixed effect changes and other covariates are assumed to be as recorded. For example, the estimated average likelihood in 2005–2006 financial year is calculated as if all episode in the study population occurred in 2005–2006 and other variables remain as they are recorded. The estimated likelihood was calculated for each level of each categorical fixed effect, and at selected point estimates for each continuous fixed effect (age, years after recognition, and summed Elix-Hauser comorbidities).

Length of stay

We conducted a multi-level Poisson regression to determine predictors of length of stay for an episode. We used the same fixed and random effects as the above model with an addition of a fixed effect of whether the episode recognised intellectual disability. We tested whether the multi-level Poisson regression was necessary with a likelihood ratio test of fit against a standard Poisson regression without a random effect of person. Finally, we calculated the estimated length of stay for each level of each variable (in the same fashion as the estimated likelihood in the model of intellectual disability recognition above).

Subset analysis

To ensure that our results were not biased by including people who were identified in the DS-MDS, PG, or SDS as having intellectual disability before they turned 18, we conducted two subset analyses (one for intellectual disability recognition, and one for length of stay) restricting the study population to only individuals who were over 18 at their index date (i.e., when they first appeared in the DS-MDS, PG, or SDS). The results of these regressions are reported alongside our other analyses for comparison.

Ethics approval

The study was approved by the NSW Population and Health Services Research Ethics Committee (HREC/13/CIPHS/7; Cancer Institute NSW reference: 2013/02/446 and Sub-study Reference number: 2019UMB0209). This approval included a waiver of informed consent.

Results

Sociodemographics and episode characteristics

Table 2 shows the sociodemographic profile of the study population, and Table 3 shows the characteristics of hospital episodes for our study population. Overall, there were 12,593 individuals with 80,960 hospital episodes in the study period. Over half of the study population were male (58.1%), 65.7% lived in major cities, and 49.9% lived in disadvantaged areas. Overall, intellectual disability was recognised in 19,261 (23.79%) of all episodes. Most episodes (51.7%) occurred after the start of the 2011 financial year in metropolitan local health districts (63.3%). Around half of all admissions were urgent episodes (50.5%). Most episodes occurred in a public hospital (92.2%), and ICD-10 chapter 21 (Factors influencing health contact) accounted for the largest percentage of episodes (23.8%), noting that this chapter includes codes that often require regular hospital admissions (such as dialysis, ICD-10 code Z49, and rehabilitation, ICD-10 code Z50). Fig 2 shows the raw proportion of hospital episodes where intellectual disability was recognised by financial year. Initially, intellectual disability was recognised in approximately 35% of hospital episodes, but this decreased in 2008–2009 to around 25% of episodes, and continued to decrease to around 20% of episodes by 2014–2015.
Table 2

Sociodemographic profile of the study population.

VariableFrequency (% of people)
Number of people 12,593
Sex
Male7,317 (58.1%)
Female5,276 (41.9%)
Age at index
Median32.8
Inter-quartile range20.0–47.1
Remoteness of area of residence
Major Cities of Australia8,275 (65.7%)
Inner Regional Australia3,022 (24.0%)
Outer Regional Australia and Beyond1,296 (10.3%)
Index of Relative Socio-economic Disadvantage Quintile
1(Most disadvantaged)2,644 (21.0%)
23,640 (28.9%)
32,633 (20.9%
41,805 (14.3%)
5 (Least disadvantaged)1,609 (12.8%)
Missing262 (2.1%)
Indigenous status 1,342 (10.7%)
Autism Spectrum Disorder 747 (5.9%)
Table 3

Characteristics of hospital episodes.

VariableFrequency (% of episodes)
Number of episodes 80,960
Intellectual disability recognition
No61,699 (76.2%)
Yes19,261 (23.8%)
Financial year
2005–20064,321 (5.3%)
2006–20075,232 (6.5%)
2007–20085,718 (7.1%)
2008–20096,910 (8.5%)
2009–20107,993 (9.9%)
2010–20118,892 (11%)
2011–20129,723 (12%)
2012–201310,674 (13.2%)
2013–201410,974 (13.6%)
2014–201510,523 (13%)
Age at episode (median (IQR))
Median39.2
Inter-quartile range26.8–51.7
Local Health District location
Metropolitan51,236 (63.3%)
Rural27,798 (34.3%)
Speciality1,926 (2.4%)
Remoteness
Major cities57,055 (70.5%)
Inner regional18,187 (22.5%)
Outer regional and beyond5,718 (7.1%)
IRSD quintile
1 (Most disadvantaged)25,535 (31.5%)
217,337 (21.4%)
317,335 (21.4%)
49,668 (11.9%)
5 (Least disadvantaged)11,085 (13.7%)
In custody at time of episode
No79,786 (98.5%)
Yes1,174 (1.5%)
Drug and alcohol disorder episode
No76,181 (94.1%)
Yes4,779 (5.9%)
Urgent admission
No40,042 (49.5%)
Yes40,918 (50.5%)
Summed Elix-Hauser comorbidities
035,279 (43.6%)
1–242,243 (52.2%)
3+3,438 (4.2%)
Hospital type
Public74,619 (92.2%)
Private6,341 (7.8%)
Diagnosis chapter
1. Infectious and parasitic1,421 (1.8%)
2. Neoplasms1,915 (2.4%)
3. Blood and blood forming877 (1.1%)
4. Endocrine1,471 (1.8%)
5. Mental and behavioural9,835 (12.1%)
6. Nervous5,804 (7.2%)
7. Eye and adnexa1,325 (1.6%)
8. Ear and mastoid387 (0.5%)
9. Circulatory1,730 (2.1%)
10. Respiratory4,964 (6.1%)
11. Digestive10,190 (12.6%)
12. Skin and subcutaneous1,992 (2.5%)
13. Musculoskeletal1,782 (2.2%)
14. Genitourinary2,853 (3.5%)
15. Pregnancy and the puerperium1,081 (1.3%)
17. Congenital and chromosomal436 (0.5%)
18. Abnormal signs and symptoms6,922 (8.5%)
19. Injury and poisoning6,743 (8.3%)
21. Factors influencing contact19,232 (23.8%)
Fig 2

Raw proportion of episodes that recognise intellectual disability (by financial year).

Diagnostic recognition of intellectual disability

Table 4 shows the results of the multi-level logistic regression predicting intellectual disability recognition within a hospital episode (with a subset analysis restricting the study population to only those with an index date after they turn 18 shown in Table 5). The multi-level logistic regression with a random effect of person provided a significantly better fit than an equivalent logistic regression without a random effect of person (2(1) > 10,000, p < .001), indicating that accounting for individual level variance improved the fit of our model. Overall, women with intellectual disability were more likely to be recognised as having an intellectual disability within a hospital episode than men (odds ratio (OR): 1.11, 95% confidence interval (CI): 1.02–1.21), and the older someone was at the time of their episode the more likely they were to be recognised as having an intellectual disability (OR: 1.01, 95%CI: 1.01–1.01). Recognition of intellectual disability decreased across financial years (χ2(9) = 1033.75, p < 0.001), but increased the more years a person had been known to disability services (OR: 1.25, 95%CI: 1.22–1.27). Episodes were more likely to recognise intellectual disability if they occurred in rural local health districts (OR: 1.51, 95%CI: 1.37–1.67), but less likely if they occurred in speciality local health districts (OR: 0.37, 95%CI: 0.29–0.46) compared to episodes that occurred in metropolitan local health districts. However, the more remote the residence of the person presenting in an episode, the less likely that episode was to recognise intellectual disability (χ2(2) = 78.48, p < 0.001). Autistic people were more likely to be recognised as having an intellectual disability (OR: 1.62, 95%CI: 1.44–2.83). Episodes where a person was in custody at the time of the episode (OR: 0.09, 95%CI: 0.05–0.15), or had drug and alcohol related diagnoses (OR: 0.68, 95%CI: 0.60–0.76), were less likely to recognise intellectual disability. Episodes that were urgent (OR: 1.37, 95%CI: 1.28–1.46) were more likely to recognise intellectual disability. A higher number of Elix-Hauser comorbidities within an episode was associated with a greater likelihood of recognition of intellectual disability (OR: 1.49, 95%CI: 1.45–1.54). Episodes that occurred in private hospitals were less likely to recognise intellectual disability (OR: 0.26, 95%CI: 0.23–0.30). The average estimated likelihoods showed episodes with a principal diagnosis in ICD-10 chapter 17 (Congenital and chromosomal) had the highest likelihood of recognising intellectual disability (marginal likelihood = 0.43, 95%CI: 0.38–0.47), while episodes where the primary diagnosis was in ICD-10 chapter 3 (Blood and blood forming) had the lowest likelihood of intellectual disability recognition (marginal likelihood = 0.20, 95%CI: 0.07–0.23). We did not observe an effect of socioeconomic disadvantage on predicting recognition of intellectual disability (χ2(4) = 7.42, p = 0.115). When considering the subset analysis with only people with index dates after they turned 18, all results were similar in their direction and significance, with the exception that there was no significant effect of sex (OR: 1.05, 95%CI: 0.96–1.16).
Table 4

Predictors of intellectual disability recognition in a hospital episode (n = 12,593).

VariableOdds Ratio (95% CI)SEp valueMarginal likelihood (95% CI)
Sex
Male Reference 0.29 (0.28, 0.30)
Female1.11 (1.02, 1.21)0.050.0200.30 (0.29, 0.31)
Age (years) 1.01 (1.01, 1.01) < .01<0.001
200.27 (0.26, 0.28)
300.28 (0.27, 0.29)
400.29 (0.29, 0.30)
500.31 (0.30, 0.32)
600.32 (0.31, 0.33)
700.34 (0.33, 0.35)
800.36 (0.34, 0.37)
Financial year <0.001
2005–2006 Reference 0.55 (0.53, 0.57)
2006–20070.90 (0.79, 1.01)0.060.0840.53 (0.51, 0.55)
2007–20080.62 (0.54, 0.70)0.04<0.0010.48 (0.46, 0.49)
2008–20090.36 (0.31, 0.41)0.02<0.0010.39 (0.38, 0.41)
2009–20100.26 (0.22, 0.30)0.02<0.0010.35 (0.34, 0.36)
2010–20110.17 (0.14, 0.20)0.01<0.0010.29 (0.28, 0.30)
2011–20120.11 (0.10, 0.13)0.01<0.0010.24 (0.23, 0.25)
2012–20130.10 (0.08, 0.12)0.01<0.0010.23 (0.22, 0.24)
2013–20140.08 (0.06, 0.09)0.01<0.0010.20 (0.19, 0.21)
2014–20150.05 (0.04, 0.07)0.01<0.0010.16 (0.15, 0.17)
Years after recognition 1.25 (1.22, 1.27)0.01<0.001
00.19 (0.18, 0.20)
20.24 (0.23, 0.25)
40.29 (0.29, 0.30)
60.35 (0.34, 0.36)
80.41 (0.40, 0.42)
100.47 (0.45, 0.49)
Local Health District location <0.001
Metropolitan Reference 0.28 (0.27, 0.29)
Rural1.51 (1.37, 1.67)0.08<0.0010.33 (0.32, 0.34)
Specialty0.37 (0.29, 0.46)0.04<0.0010.17 (0.15, 0.19)
Remoteness <0.001
Major cities Reference 0.31 (0.31, 0.32)
Inner regional0.68 (0.61, 0.76)0.04<0.0010.26 (0.25, 0.27)
Outer regional and beyond0.50 (0.42, 0.59)0.04<0.0010.23 (0.21, 0.25)
IRSD quintile 0.115
1 (Most disadvantaged) Reference 0.29 (0.28, 0.30)
21.09 (0.99, 1.19)0.050.0870.30 (0.29, 0.31)
31.00 (0.91, 1.11)0.050.9430.29 (0.28, 0.30)
41.13 (1.00, 1.27)0.070.0480.31 (0.29, 0.32)
5 (Least disadvantaged)1.01 (0.89, 1.14)0.060.9250.29 (0.28, 0.31)
In custody at time of episode
No Reference 0.30 (0.29, 0.30)
Yes0.09 (0.05, 0.15)0.02<0.0010.08 (0.05, 0.11)
Drug and alcohol episode
No Reference 0.30 (0.29, 0.30)
Yes0.68 (0.60, 0.76)0.04<0.0010.25 (0.24, 0.26)
Presence of Autism Spectrum Disorder
No Reference 0.29 (0.28, 0.30)
Yes1.62 (1.44, 1.83)0.10<0.0010.35 (0.34, 0.37)
Urgent admission
No Reference 0.27 (0.27, 0.28)
Yes1.37 (1.28, 1.46)0.05<0.0010.31 (0.31, 0.32)
Summed Elix-Hauser comorbidities 1.49 (1.45, 1.54)0.02<0.001
00.26 (0.25, 0.26)
10.31 (0.30, 0.31)
20.36 (0.35, 0.37)
30.42 (0.41, 0.43)
Hospital type
Public Reference 0.31 (0.30, 0.31)
Private0.26 (0.23, 0.30)0.02<0.0010.16 (0.15, 0.17)
Diagnosis chapter <0.001
5. Mental and behavioural Reference 0.41 (0.40, 0.43)
1. Infectious and parasitic0.33 (0.28, 0.39)0.03<0.0010.26 (0.24, 0.28)
2. Neoplasms0.22 (0.18, 0.26)0.02<0.0010.21 (0.20, 0.23)
3. Blood and blood forming0.19 (0.14, 0.25)0.03<0.0010.20 (0.17, 0.23)
4. Endocrine0.37 (0.31, 0.44)0.03<0.0010.28 (0.25, 0.30)
6. Nervous0.33 (0.29, 0.37)0.02<0.0010.26 (0.25, 0.27)
7. Eye and adnexa0.31 (0.25, 0.37)0.03<0.0010.25 (0.23, 0.28)
8. Ear and mastoid0.34 (0.24, 0.48)0.06<0.0010.27 (0.22, 0.31)
9. Circulatory0.28 (0.24, 0.34)0.02<0.0010.24 (0.23, 0.26)
10. Respiratory0.46 (0.41, 0.52)0.03<0.0010.30 (0.29, 0.32)
11. Digestive0.44 (0.39, 0.48)0.02<0.0010.30 (0.29, 0.31)
12. Skin and subcutaneous0.27 (0.23, 0.32)0.02<0.0010.24 (0.22, 0.26)
13. Musculoskeletal0.31 (0.26, 0.36)0.03<0.0010.25 (0.23, 0.27)
14. Genitourinary0.31 (0.27, 0.36)0.02<0.0010.25 (0.24, 0.27)
15. Pregnancy and the puerperium0.34 (0.25, 0.44)0.05<0.0010.26 (0.23, 0.30)
17. Congenital and chromosomal1.11 (0.81, 1.52)0.180.5040.43 (0.38, 0.47)
18. Abnormal signs and symptoms0.33 (0.30, 0.37)0.02<0.0010.26 (0.25, 0.27)
19. Injury and poisoning0.46 (0.42, 0.51)0.02<0.0010.31 (0.29, 0.32)
21. Factors influencing contact0.43 (0.38, 0.48)0.03<0.0010.29 (0.28, 0.31)

SE: Standard error.

Table 5

Subset analysis of predictors of intellectual disability recognition in a hospital episode for people with index dates after they turn 18 (n = 10,473).

VariableIncident Rate Ratio (95% CI)SEp valueMarginal length of stay (95% CI)
Sex
Male Reference 0.30 (0.30, 0.31)
Female1.05 (0.96, 1.16)0.050.277*0.31 (0.30, 0.32)
Age (years) 1.01 (1.01, 1.01) < .01<0.001
200.29 (0.27, 0.30)
300.29 (0.29, 0.30)
400.30 (0.30, 0.31)
500.31 (0.31, 0.32)
600.32 (0.31, 0.33)
700.33 (0.32, 0.35)
800.34 (0.32, 0.36)
Financial year <0.001
2005–2006 Reference 0.56 (0.54, 0.58)
2006–20070.90 (0.79, 1.02)0.060.0960.55 (0.53, 0.56)
2007–20080.61 (0.53, 0.70)0.04<0.0010.49 (0.47, 0.50)
2008–20090.35 (0.30, 0.40)0.02<0.0010.40 (0.39, 0.42)
2009–20100.25 (0.22, 0.29)0.02<0.0010.36 (0.34, 0.37)
2010–20110.16 (0.14, 0.19)0.01<0.0010.30 (0.28, 0.31)
2011–20120.11 (0.09, 0.13)0.01<0.0010.25 (0.24, 0.26)
2012–20130.09 (0.08, 0.11)0.01<0.0010.23 (0.22, 0.24)
2013–20140.07 (0.06, 0.09)0.01<0.0010.20 (0.19, 0.21)
2014–20150.05 (0.04, 0.06)0.01<0.0010.16 (0.15, 0.17)
Years after recognition 1.27 (1.24, 1.30)0.01<0.001
00.20 (0.19, 0.21)
20.25 (0.24, 0.26)
40.31 (0.30, 0.31)
60.37 (0.36, 0.38)
80.43 (0.42, 0.45)
100.50 (0.48, 0.52)
Local Health District location <0.001
Metropolitan Reference 0.29 (0.28, 0.30)
Rural1.59 (1.42, 1.77)0.09<0.0010.35 (0.34, 0.36)
Speciality0.38 (0.30, 0.49)0.05<0.0010.18 (0.15, 0.20)
Remoteness <0.001
Major cities Reference 0.33 (0.32, 0.33)
Inner regional0.66 (0.59, 0.74)0.04<0.0010.27 (0.26, 0.28)
Outer regional and beyond0.46 (0.38, 0.55)0.04<0.0010.23 (0.21, 0.25)
IRSD quintile 0.110
1 (Most disadvantaged) Reference 0.30 (0.29, 0.32)
21.04 (0.94, 1.15)0.050.4510.31 (0.30, 0.32)
30.98 (0.88, 1.1)0.050.7710.30 (0.29, 0.31)
41.14 (1.00, 1.29)0.070.0460.32 (0.31, 0.34)
5 (Least disadvantaged)0.97 (0.85, 1.11)0.070.6780.30 (0.29, 0.31)
Custody flag
No Reference 0.31 (0.3, 0.32)
Yes0.09 (0.05, 0.17)0.03<0.0010.08 (0.05, 0.12)
Drug and alcohol flag
No Reference 0.31 (0.30, 0.32)
Yes0.61 (0.54, 0.70)0.04<0.0010.25 (0.23, 0.26)
Autism Spectrum Disorder flag
No Reference 0.30 (0.29, 0.31)
Yes1.55 (1.35, 1.78)0.11<0.0010.36 (0.34, 0.38)
Emergency admission flag
No Reference 0.28 (0.28, 0.29)
Yes1.5 (1.45, 1.55)0.02<0.0010.33 (0.32, 0.34)
Summed Elix-Hauser comorbidities 1.39 (1.30, 1.49)0.05<0.001
00.26 (0.26, 0.27)
10.32 (0.31, 0.32)
20.37 (0.36, 0.38)
30.43 (0.42, 0.45)
Hospital type
Public Reference 0.32 (0.31, 0.32)
Private0.27 (0.24, 0.31)0.02<0.0010.17 (0.16, 0.18)
Diagnosis chapter <0.001
5. Mental and behavioural Reference 0.42 (0.41, 0.43)
1. Infectious and parasitic0.36 (0.30, 0.43)0.03<0.0010.28 (0.26, 0.30)
2. Neoplasms0.22 (0.18, 0.27)0.02<0.0010.22 (0.2, 0.24)
3. Blood and blood forming0.19 (0.14, 0.25)0.03<0.0010.20 (0.17, 0.23)
4. Endocrine0.39 (0.32, 0.47)0.04<0.0010.29 (0.27, 0.31)
6. Nervous0.33 (0.29, 0.38)0.02<0.0010.27 (0.26, 0.28)
7. Eye and adnexa0.31 (0.26, 0.39)0.03<0.0010.26 (0.24, 0.29)
8. Ear and mastoid0.32 (0.22, 0.46)0.06<0.0010.26 (0.22, 0.31)
9. Circulatory0.29 (0.24, 0.34)0.03<0.0010.25 (0.23, 0.27)
10. Respiratory0.48 (0.42, 0.55)0.03<0.0010.32 (0.30, 0.33)
11. Digestive0.45 (0.40, 0.50)0.03<0.0010.31 (0.30, 0.32)
12. Skin and subcutaneous0.30 (0.26, 0.36)0.03<0.0010.26 (0.24, 0.28)
13. Musculoskeletal0.31 (0.26, 0.38)0.03<0.0010.26 (0.24, 0.28)
14. Genitourinary0.33 (0.29, 0.39)0.03<0.0010.27 (0.25, 0.29)
15. Pregnancy and the puerperium0.38 (0.27, 0.52)0.06<0.0010.29 (0.24, 0.33)
17. Congenital and chromosomal1.23 (0.86, 1.77)0.230.2640.45 (0.40, 0.51)
18. Abnormal signs and symptoms0.33 (0.30, 0.37)0.02<0.0010.27 (0.26, 0.28)
19. Injury and poisoning0.50 (0.44, 0.55)0.03<0.0010.32 (0.31, 0.33)
21. Factors influencing contact0.45 (0.40, 0.52)0.03<0.0010.31 (0.29, 0.32)

SE: Standard error.

*Indicates difference in significance from main analysis

SE: Standard error. SE: Standard error. *Indicates difference in significance from main analysis

Length of hospital episode

Table 6 shows the results of the multi-level logistic regression predicting intellectual disability recognition within a hospital episode (with a sensitivity analysis restricting the study population to only those with an index date after they turn 18 shown in Table 7). The multi-level Poisson regression with a random effect of person provided a significantly better fit than an equivalent Poison regression without a random effect of person (2(1) > 10,000, p < .001), indicating that accounting for individual level variance improved the fit of our model. Notably, episodes where intellectual disability was recognised were substantially longer than those where intellectual disability was not recognised (IRR: 1.57, 95%CI: 1.56–1.59). The subset analysis with only people with index dates after they turned 18 showed a similar effect of intellectual disability recognition on length of stay (IRR: 1.59, 95%CI: 1.57–1.60)
Table 6

Predictors of length of hospital episode in days (n = 12,593).

VariableIncident Rate Ratio (95% CI)SEp valueMarginal length of stay (95% CI)
Intellectual disability recognition
No Reference 3.94 (3.81, 4.07)
Yes1.57 (1.56, 1.59)0.01<0.0016.20 (6.00, 6.41)
Sex
Male Reference 5.15 (4.96, 5.34)
Female0.68 (0.66, 0.70)0.01<0.0013.51 (3.39, 3.64)
Age (years) 0.99 (0.99, 0.99) < .01<0.001
205.42 (5.18, 5.65)
304.86 (4.69, 5.04)
404.37 (4.23, 4.51)
503.92 (3.8, 4.05)
603.53 (3.40, 3.65)
703.17 (3.02, 3.31)
802.84 (2.69, 3.00)
Financial year <0.001
2005–2006 Reference 4.34 (4.1, 4.59)
2006–20071.00 (0.98, 1.03)0.010.7424.36 (4.14, 4.59)
2007–20081.04 (1.01, 1.07)0.010.0074.51 (4.30, 4.72)
2008–20091.06 (1.02, 1.09)0.020.0014.59 (4.40, 4.78)
2009–20101.12 (1.08, 1.16)0.02<0.0014.85 (4.67, 5.03)
2010–20111.20 (1.15, 1.25)0.03<0.0015.20 (5.02, 5.38)
2011–20121.04 (0.99, 1.09)0.030.1614.50 (4.34, 4.65)
2012–20130.97 (0.92, 1.02)0.030.2804.22 (4.07, 4.36)
2013–20140.92 (0.86, 0.98)0.030.0063.99 (3.85, 4.14)
2014–20150.97 (0.91, 1.04)0.030.3694.21 (4.04, 4.38)
Years after recognition 1.06 (1.05, 1.07) < .01<0.001
03.47 (3.33, 3.61)
23.90 (3.77, 4.04)
44.39 (4.24, 4.53)
64.93 (4.75, 5.12)
85.55 (5.29, 5.81)
106.24 (5.88, 6.60)
Local Health District location <0.001
Metropolitan Reference 4.18 (4.04, 4.32)
Rural1.15 (1.12, 1.17)0.01<0.0014.79 (4.62, 4.96)
Specialty1.20 (1.17, 1.23)0.02<0.0015.03 (4.83, 5.23)
Remoteness <0.001
Major cities Reference 4.37 (4.22, 4.52)
Inner regional1.07 (1.05, 1.10)0.01<0.0014.69 (4.52, 4.87)
Outer regional and beyond0.96 (0.93, 1.01)0.020.0894.22 (4.01, 4.42)
IRSD quintile <0.001
1 (Most disadvantaged) Reference 3.90 (3.77, 4.03)
21.11 (1.08, 1.13)0.01<0.0014.31 (4.16, 4.46)
31.32 (1.29, 1.34)0.01<0.0015.13 (4.95, 5.31)
41.41 (1.38, 1.44)0.02<0.0015.49 (5.29, 5.70)
5 (Least disadvantaged)1.07 (1.04, 1.09)0.01<0.0014.16 (4.01, 4.31)
In custody at time of episode
No Reference 4.25 (4.11, 4.38)
Yes2.95 (2.85, 3.06)0.05<0.00112.55 (11.97, 13.13)
Drug and alcohol episode
No Reference 4.43 (4.28, 4.57)
Yes1 (0.99, 1.02)0.010.5474.45 (4.29, 4.61)
Presence of Autism Spectrum Disorder
No Reference 4.14 (4.01, 4.28)
Yes1.77 (1.66, 1.89)0.06<0.0017.33 (6.82, 7.85)
Urgent admission
No Reference 4.82 (4.66, 4.98)
Yes0.85 (0.84, 0.86) < .01<0.0014.10 (3.96, 4.23)
Summed Elix-Hauser comorbidities 1.56 (1.55, 1.57) < .01<0.001
02.88 (2.78, 2.97)
14.49 (4.34, 4.63)
27.00 (6.77, 7.23)
310.92 (10.55, 11.29)
Hospital type
Public Reference 4.48 (4.33, 4.63)
Private0.80 (0.79, 0.82)0.01<0.0013.60 (3.46, 3.74)
Diagnosis chapter <0.001
5. Mental and behavioural Reference 6.49 (6.28, 6.71)
1. Infectious and parasitic0.51 (0.49, 0.52)0.01<0.0013.30 (3.16, 3.43)
2. Neoplasms0.45 (0.43, 0.46)0.01<0.0012.89 (2.77, 3.01)
3. Blood and blood forming0.35 (0.33, 0.36)0.01<0.0012.25 (2.12, 2.38)
4. Endocrine0.48 (0.47, 0.50)0.01<0.0013.12 (2.99, 3.25)
6. Nervous0.39 (0.38, 0.40) < .01<0.0012.55 (2.46, 2.64)
7. Eye and adnexa0.29 (0.28, 0.31)0.01<0.0011.89 (1.78, 1.99)
8. Ear and mastoid0.32 (0.29, 0.35)0.02<0.0012.07 (1.85, 2.30)
9. Circulatory0.43 (0.42, 0.45)0.01<0.0012.81 (2.70, 2.93)
10. Respiratory0.57 (0.56, 0.58)0.01<0.0013.68 (3.56, 3.81)
11. Digestive0.39 (0.38, 0.39) < .01<0.0012.51 (2.42, 2.6)
12. Skin and subcutaneous0.68 (0.66, 0.70)0.01<0.0014.42 (4.24, 4.59)
13. Musculoskeletal0.56 (0.55, 0.58)0.01<0.0013.66 (3.51, 3.81)
14. Genitourinary0.45 (0.44, 0.46)0.01<0.0012.90 (2.79, 3.02)
15. Pregnancy and the puerperium0.74 (0.70, 0.78)0.02<0.0014.79 (4.51, 5.06)
17. Congenital and chromosomal0.71 (0.67, 0.75)0.02<0.0014.61 (4.32, 4.90)
18. Abnormal signs and symptoms0.35 (0.34, 0.36) < .01<0.0012.28 (2.20, 2.36)
19. Injury and poisoning0.62 (0.61, 0.63)0.01<0.0014.05 (3.91, 4.19)
21. Factors influencing contact1.06 (1.04, 1.08)0.01<0.0016.89 (6.66, 7.13)

SE: Standard Error.

Table 7

Subset analysis of predictors of length of hospital episode in days for people with index dates after they turn 18 (n = 10,473).

VariableIncident Rate Ratio (95% CI)SEp valueMarginal length of stay (95% CI)
Intellectual disability recognition
No Reference 4.42 (4.23, 4.61)
Yes1.59 (1.57, 1.60)0.01<0.0017.02 (6.72, 7.31)
Sex
Male Reference 5.88 (5.61, 6.14)
Female0.65 (0.63, 0.67)0.01<0.0013.81 (3.65, 3.98)
Age (years) 0.99 (0.99, 0.99) < .01<0.001
206.22 (5.86, 6.58)
305.59 (5.32, 5.85)
405.02 (4.81, 5.22)
504.51 (4.33, 4.68)
604.05 (3.88, 4.22)
703.64 (3.46, 3.82)
803.27 (3.07, 3.46)
Financial year <0.001
2005–2006 Reference 4.92 (4.6, 5.25)
2006–20071.01 (0.98, 1.04)0.010.4294.98 (4.68, 5.27)
2007–20081.05 (1.02, 1.08)0.020.0005.19 (4.91, 5.47)
2008–20091.04 (1.01, 1.08)0.020.0205.12 (4.87, 5.38)
2009–20101.12 (1.07, 1.16)0.02<0.0015.49 (5.24, 5.75)
2010–20111.21 (1.16, 1.26)0.03<0.0015.95 (5.69, 6.21)
2011–20121.02 (0.97, 1.08)0.030.3975.04 (4.82, 5.25)
2012–20130.97 (0.91, 1.02)0.030.2344.75 (4.55, 4.96)
2013–20140.89 (0.84, 0.95)0.030.0014.40 (4.20, 4.60)
2014–20150.92 (0.86, 0.99)0.030.0294.54 (4.32, 4.76)
Years after recognition 1.06 (1.05, 1.07) < .01<0.001
03.90 (3.71, 4.09)
24.41 (4.22, 4.60)
44.99 (4.78, 5.20)
65.64 (5.37, 5.91)
86.37 (6.01, 6.74)
107.21 (6.71, 7.71)
Local Health District location <0.001
Metropolitan Reference 4.64 (4.45, 4.84)
Rural1.19 (1.17, 1.22)0.01<0.0015.55 (5.30, 5.79)
Speciality1.11 (1.08, 1.14)0.02<0.0015.16 (4.91, 5.42)
Remoteness <0.001
Major cities Reference 4.88 (4.67, 5.09)
Inner regional1.10 (1.07, 1.13)0.02<0.0015.35 (5.10, 5.59)
Outer regional and beyond0.95 (0.91, 1.00)0.020.029*4.65 (4.39, 4.91)
IRSD quintile <0.001
1 (Most disadvantaged) Reference 4.25 (4.07, 4.43)
21.11 (1.09, 1.13)0.01<0.0014.72 (4.51, 4.93)
31.40 (1.38, 1.43)0.01<0.0015.97 (5.7, 6.23)
41.51 (1.47, 1.55)0.02<0.0016.42 (6.12, 6.71)
5 (Least disadvantaged)1.11 (1.08, 1.14)0.01<0.0014.72 (4.51, 4.93)
Custody flag
No Reference 4.74 (4.55, 4.93)
Yes3.1 (2.99, 3.21)0.06<0.00114.69 (13.91, 15.47)
Drug and alcohol flag
No Reference 4.97 (4.76, 5.18)
Yes1.01 (0.99, 1.02)0.010.5335.00 (4.77, 5.22)
Autism Spectrum Disorder flag
No Reference 4.61 (4.42, 4.8)
Yes2.08 (1.91, 2.26)0.09<0.0019.58 (8.72, 10.45)
Emergency admission flag
No Reference 5.42 (5.19, 5.65)
Yes0.84 (0.83, 0.85) < .01<0.0014.56 (4.37, 4.76)
Summed Elix-Hauser comorbidities 1.56 (1.55, 1.56) < .01<0.001
03.18 (3.05, 3.31)
14.96 (4.75, 5.16)
27.72 (7.39, 8.04)
312.03 (11.51, 12.54)
Hospital type
Public Reference 5.03 (4.82, 5.24)
Private0.77 (0.76, 0.79)0.010.0003.90 (3.71, 4.08)
Diagnosis chapter <0.001
5. Mental and behavioural Reference 7.33 (7.02, 7.64)
1. Infectious and parasitic0.49 (0.48, 0.51)0.01<0.0013.60 (3.42, 3.78)
2. Neoplasms0.42 (0.41, 0.43)0.01<0.0013.08 (2.93, 3.23)
3. Blood and blood forming0.33 (0.31, 0.35)0.01<0.0012.43 (2.28, 2.59)
4. Endocrine0.47 (0.45, 0.48)0.01<0.0013.43 (3.26, 3.60)
6. Nervous0.37 (0.36, 0.38) < .01<0.0012.73 (2.61, 2.85)
7. Eye and adnexa0.28 (0.27, 0.30)0.01<0.0012.08 (1.94, 2.21)
8. Ear and mastoid0.31 (0.27, 0.34)0.02<0.0012.25 (1.98, 2.51)
9. Circulatory0.42 (0.41, 0.43)0.01<0.0013.09 (2.94, 3.23)
10. Respiratory0.55 (0.54, 0.56)0.01<0.0014.04 (3.86, 4.21)
11. Digestive0.37 (0.37, 0.38) < .01<0.0012.74 (2.63, 2.86)
12. Skin and subcutaneous0.66 (0.64, 0.68)0.01<0.0014.82 (4.59, 5.05)
13. Musculoskeletal0.56 (0.55, 0.58)0.01<0.0014.12 (3.92, 4.32)
14. Genitourinary0.44 (0.43, 0.45)0.01<0.0013.22 (3.07, 3.37)
15. Pregnancy and the puerperium0.68 (0.64, 0.72)0.02<0.0014.97 (4.63, 5.32)
17. Congenital and chromosomal0.60 (0.56, 0.64)0.02<0.0014.38 (4.04, 4.72)
18. Abnormal signs and symptoms0.34 (0.33, 0.35) < .01<0.0012.48 (2.38, 2.59)
19. Injury and poisoning0.62 (0.61, 0.63)0.01<0.0014.56 (4.37, 4.76)
21. Factors influencing contact1.05 (1.03, 1.07)0.01<0.0017.71 (7.38, 8.04)

SE: Standard error.

*Indicates difference in significance from main analysis

SE: Standard Error. SE: Standard error. *Indicates difference in significance from main analysis

Discussion

The current study aimed to investigate the factors associated with recognition of intellectual disability during an inpatient episode in adults, and how this recognition affects the length of inpatient episodes in a population of people with intellectual disability from NSW, Australia. We ran two mixed-effect regressions, one predicting the presence of an intellectual disability diagnosis during an inpatient episode, and one predicting the length of stay of an inpatient episode for adults with intellectual disability. We found that recognition of intellectual disability during an episode was more likely if the person was a woman, was older, had been known to disability services for a longer period of time, was Autistic, or had a high number of Elix-Hauser comorbidities, and was also more likely if the episode occurred in a rural local health district, or was an urgent admission. Recognition of intellectual disability during an episode was less likely if the episode occurred in a specialty local health network, occurred in a private hospital, occurred while the person was in custody, had a drug or alcohol related code recorded, or the person lived outside a major city. For length of stay, we found that the recognition of intellectual disability in an inpatient episode predicted a longer length of stay, after controlling for other demographic and health variables. Taken together, our findings suggest that adults with more complex health needs are more likely to be recognised as having intellectual disability, but adults with complexity across other domains (such as drug and alcohol problems, and contacts with the justice system) are less likely to be recognised as having an intellectual disability. Overall, recognition of intellectual disability was low at only 23.79% of all episodes. Further, recognition of intellectual disability decreased over time, as evidenced by both the raw number of episodes where intellectual disability was recognised, and from the multi-level logistic regression controlling for other demographic and health variables. In contrast, recognition of intellectual disability increased the longer a person had been known to disability services. That is, though individuals were less likely overall to be recognised as having intellectual disability in the later years of the study period, those that had been known to disability services for a longer time were more likely to be recognised than those that had been known for a short time in those later years. These patterns of recognition in an acute health care setting over time and as a function of recency of intellectual disability diagnosis in disability services are concerning, particularly as they appear to be at loggerheads with attempts to improve integration between health and disability services in NSW in that period [35, 36]. Despite low overall recognition of intellectual disability, one encouraging aspect of our results is that they suggest adults with more complex health needs are more likely to be recognised as having intellectual disability during an inpatient stay. Specifically, Autistic people, people with high Elix-Hauser comorbidities score recorded in an episode, or people visiting hospital for an urgent admission were more likely to be recognised as having an intellectual disability. These factors may reflect that people with more obvious disability and complex needs are more likely to be recognised as having intellectual disability than people with milder intellectual disability and correspondingly lower support needs [20]. For example, Autism Spectrum Disorders are more common in those with a greater level of intellectual disability [27]. Though complex health needs predicted intellectual disability recognition, we found that episodes with complexity across other domains, such as episodes with drug and alcohol related codes, or episodes that occurred while the individual was in custody, predicted a decreased chance of intellectual disability recognition. This difference was particularly stark for individuals in custody, where fewer than 10% of episodes that occurred when the individual was in custody recognised intellectual disability. Our findings are particularly concerning given the over-representation of individuals with intellectual disability in custody, and their need for extra support (not less) to prevent recidivism [21]. Overall, the results suggest a blindness to the presence of intellectual disability in such individuals, risking lack of activation of supports in areas that are critical to their future trajectory. Our findings complement and extend those of Bourke et al., who examined predictors of intellectual disability recognition in children in Western Australia [20]. Similar to their findings, our studied showed that females admitted to hospital were more likely to be recognised as having intellectual disability than males, though we note that in our study the effect of sex was not significant when we excluded adults who first appeared in the DS-MDS, PG, or SDS prior to turning 18. Furthermore, both our study and their study indicated that those with severe intellectual disability were more likely to be recognised as having an intellectual disability in hospital (suggested by a greater likelihood for Autistic people, people with high Elix-Hauser comorbidities score recorded in an episode, or people visiting hospital for an urgent admission to be recognised as having intellectual disability). We extend the work of Bourke et al. through the addition of more variables about an individual’s profile (such as whether the person is Autistic, or currently in custody), as well as the addition of variables surrounding the hospital itself during an admission (such as whether the hospital was in a rural or metropolitan area, and whether it was a public or private hospital). Overall, our work expands our understanding of the recognition of intellectual disability in hospitals to adults, and shows that there are notable similarities between children and adults when it comes to the recognition of intellectual disability in hospital. For length of stay, episodes where intellectual disability was recognised were around 60% longer than episodes where it was not. It is likely that those with more complex health needs are more likely to both require longer inpatient stays and be recognised as having intellectual disability. Extended episode length could be mitigated by the activation of reasonable adjustments, which may assist more assertive addressing of complex health needs and coordinate supports required for earlier discharge. Our data points do not afford us knowledge of whether adjustments were applied and nor is their application mandatory within the health service system in Australia. A requirement to both identify those with intellectual disability, and implement reasonable adjustments would afford potential to optimise the health care journey for a person with intellectual disability. Should such data on mandatory adjustments be available to researchers, the impact of this strategy on the health care experience or people with intellectual disability could be evaluated from multiple perspectives. Taken together, our results support previous research on the need for more consistent recognition of intellectual disability when receiving health services [11, 20]. Low recognition rates of intellectual disability highlight a major barrier to providing reasonable adjustments in health care settings for people with intellectual disability, particularly for those in contact with the justice system, and those presenting to hospital for reasons related to drug and alcohol use. To address the issue of low recognition, we advocate for the introduction of disability specific flags within hospital records that code for the presence, type, and severity of a person’s disability when they present to hospital. Ideally, such a flag would be linked with national databases tracking such information for people with disability (such as the Reasonable Adjustments Flag in the United Kingdom, or the proposed National Disability Data Asset in Australia) [17, 37]. Overall, our results suggest that recognition of intellectual disability has been historically poor, and more needs to be done to assure that people with intellectual disability can receive the best possible health care when they come into contact with health services.

Strengths and limitations

A key strength of this study was the ability to leverage a large amount of population-level hospital data from a broad period. However, this approach also has its limitations. Though we could identify from our dataset whether intellectual disability had been recorded as an ICD-10 code during an inpatient episode, the absence of this record does not necessarily guarantee that the hospital was not aware that an individual had an intellectual disability. However, we believe that it does provide a reasonable proxy for recognition of intellectual disability in the absence of other information, and feel this further highlights the need for a flag for intellectual disability to be included as standard in hospital records. Also, we were not able to directly determine the severity of an individual’s intellectual disability, and as discussed it is likely that there is some overlap between the severity of the disability and the likelihood that it is recognised during an inpatient episode. However, this fact does not account for the low absolute amount of recognition across the episodes. Finally, the estimated marginal proportion of recognition per financial year in our model (Table 3) was different from the crude observed proportions despite showing the same trend (Fig 1). The difference is expected as the model controls for other variables that the crude proportion does not.

Conclusions

Identification of intellectual disability during contact with health services is critical to providing reasonable adjustments to health provision to assure the best health outcomes for adults with intellectual disability. The current study examined demographic and health predictors of intellectual disability recognition in inpatient episodes in NSW, Australia. Overall, we find that complex health needs appear to predict the recognition of intellectual disability, those with complex needs across other domains (such as drug and alcohol problems, contacts with the justice system) have a suppressive effect on recognising intellectual disability, and recognition of intellectual disability was associated with longer hospital stays. Despite an increased likelihood of recognition for those with complex health care needs, overall rates of recognition (20% to 35%) are still unacceptably low. The introduction of targeted initiatives, such as the development of an intellectual disability specific flag in hospital records, may help improve the recognition of intellectual disability during contact with health services, and aid in the provision of reasonable adjustments for people with intellectual disability. 23 Nov 2021
PONE-D-21-32313
Predictors and outcomes of recognition of intellectual disability for adults during hospital admissions: A retrospective data linkage study in NSW, Australia
PLOS ONE Dear Dr. Trollor, Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process. Please submit your revised manuscript by Jan 07 2022 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file. Please include the following items when submitting your revised manuscript:
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If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice. Additional Editor Comments: Please revise the manuscript according to the reviewer's comments and advise. Please see my some concerns as follow: 1) What is your rationale for selecting variables in Table 2? 2) Table 2 may be developed for considering all variables from Table 1. 3) What is your protocol for adding variables in the regression model? 4) It would be better more productive to add supplementary tables in the manuscript as follow Table 3.1-Table 3.3 (Table 3). 5) The discussion section can be revised to incorporate the comparisons and contrast findings. [Note: HTML markup is below. Please do not edit.] Reviewers' comments: Reviewer's Responses to Questions Comments to the Author 1. Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented. Reviewer #1: Yes ********** 2. Has the statistical analysis been performed appropriately and rigorously? Reviewer #1: Yes ********** 3. Have the authors made all data underlying the findings in their manuscript fully available? The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. 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Discussion: • The author thoroughly detailed the result section here. The author gave no perspective or comparison. • The authors also failed to cite many related articles ********** 6. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files. If you choose “no”, your identity will remain anonymous but your review may still be made public. Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy. Reviewer #1: No [NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". 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6 Jan 2022 Editor: 1) What is your rationale for selecting variables in Table 2? Response: Our variables were selected based on discussion between the authors (using expert knowledge and referring to previous literature) on what variables our dataset would be important in predicting the recognition of intellectual disability. To clarify this in our manuscript, we have added a section explaining our rationale for variable selection in the Methods section on pages 9 & 10. We have also included references to additional literature that were used when selecting our variables. The section now reads: Fixed effects for the multi-level regression can be seen in Table 1. From the variables available in our datasets, we selected fixed effects for our models through a combination of expert medical knowledge about intellectual disability (JT), and internal discussion between the authors based on previous literature. [9,20,27] We included all variables selected in our analysis of intellectual disability recognition as fixed effects (besides intellectual disability recognition, which was the outcome variable for this model). Most fixed effects included were at the episode level (i.e., from data obtained directly from the records in that episode), with some variables (including age, Aboriginal and Torres Strait Islander Status, presence of Autism Spectrum Disorder) determined for each person based on the linkage method described in Reppermund et al.[22] We used ICD-10 chapter 5 as the reference level for the principal diagnosis chapter variable as most ICD-10 codes for intellectual disability are in this chapter (and may include cases where the principal diagnosis was intellectual disability). We included a random effect of person identifier into the model. We did not include any ICD10 chapters where there were no records. 2) Table 2 may be developed for considering all variables from Table 1. Response: Currently, Table 2 includes only person level variables from Table 1 to give a snap-shot of the people in our cohort. We have now added a new Table 3 that details the episode level variables for all admissions in our cohort on page 16. 3) What is your protocol for adding variables in the regression model? Response: All variables that were selected as potentially relevant to our question based on internal discussion and prior literature were included in our regression model. As such, we hope this point is adequately addressed within our manuscript the changes in response to point 1. The variables in the regression model are select priori and we did not employ any statistical method for the variable selection. 4) It would be better more productive to add supplementary tables in the manuscript as follow Table 3.1-Table 3.3 (Table 3). Response: We have added our tables previously in the supplementary to the manuscript (noting that we no longer have a supplementary document). We have included the full regression results from the length of stay analysis as its own table (rather than as Table 4.2) as it we felt that it was more natural in the flow of the manuscript. These new tables are on pages 22-23 & 25-29. We have also included some additional exposition to better explain the tables on page 12. It reads: To ensure that our results were not biased by including people who were identified in the DS-MDS, PG, or SDS as having intellectual disability before they turned 18, we conducted two subset analyses (one for intellectual disability recognition, and one for length of stay) restricting the study population to only individuals who were over 18 at their index date (i.e., when they first appeared in the DS-MDS, PG, or SDS). The results of these regressions are reported alongside our other analyses for comparison. We have also mentioned the results of these regressions explicitly on pages 19 and 24. 5) The discussion section can be revised to incorporate the comparisons and contrast findings. Response: We have expanded on our discussion on page 32 to compare and contrast our findings to those of Bourke et al., whose work we cite as a motivating paper in our introduction. The new paragraph in the discussion reads as below: Our findings complement and extend those of Bourke et al., who examined predictors of intellectual disability recognition in children in Western Australia.[20] Similar to their findings, our studied showed that females admitted to hospital were more likely to be recognised as having intellectual disability than males, though we note that in our study the effect of sex was not significant when we excluded adults who first appeared in the DS-MDS, PG, or SDS prior to turning 18. Furthermore, both our study and their study indicated that those with severe intellectual disability were more likely to be recognised as having an intellectual disability in hospital (suggested by a greater likelihood for Autistic people, people with high Elix-Hauser comorbidities score recorded in an episode, or people visiting hospital for an urgent admission to be recognised as having intellectual disability). We extend the work of Bourke et al. through the addition of more variables about an individual’s profile (such as whether the person is Autistic, or currently in custody), as well as the addition of variables surrounding the hospital itself during an admission (such as whether the hospital was in a rural or metropolitan area, and whether it was a public or private hospital). Overall, our work expands our understanding of the recognition of intellectual disability in hospitals to adults, and shows that there are notable similarities between children and adults when it comes to the recognition of intellectual disability in hospital. Reviewer 1: 1) Abstract: It would be great if the author could elaborate on the result of this study a bit. Response: We have attempted to add more to our abstract on our results, noting that we are already close to the abstract word limit. Our new abstract dedicates over one-third of its words to the results (starting from “We found an overall low rate of recognition…” to “Recognition of intellectual disability was associated with longer episodes of care…”, though this could be increased further at the discretion of the editor. The new abstract in full reads: Adults with intellectual disability have high health care needs. Despite frequent contact with health services, they often receive inadequate health care. One method to improve health care delivery is reasonable adjustments, that is, the adaptation of health care delivery such that barriers to participation are removed for the person with disability. A starting point for the provision of reasonable adjustments is recognition of intellectual disability during the health care contact. To determine rates and predictors of the recognition of intellectual disability during hospital admissions, and its impact on admission metrics, we examined a population of adults with intellectual disability identified from disability services datasets from New South Wales, Australia between 2005 and 2014. Recognition of intellectual disability was determined by the recording of an International Classification of Diseases 10th revision (ICD-10) diagnostic code for intellectual disability during a given hospital admission. We examined how recognition of intellectual disability related to length of hospital episodes. We found an overall low rate of recognition of intellectual disability (23.79%) across all hospital episodes, with the proportion of hospital episodes recognising intellectual disability decreasing from 2005-2015. Admissions for adults with complex health profiles (e.g., those with many comorbidities, those with Autism Spectrum Disorder, and those admitted for urgent treatment) were more likely to recognise intellectual disability, but admissions for adults with complexity in other domains (i.e., for those in custody, or those with drug and alcohol disorders) were less likely to recognise intellectual disability. Recognition of intellectual disability was associated with longer episodes of care, possibly indicating the greater provision of reasonable adjustments. To improve the recognition of intellectual disability for adults during health service contacts, we advocate for the implementation of targeted initiatives (such as a nationwide disability flag to be included in health service records) to improve the provision of reasonable adjustments. 2) Method: Definition of the study population is missing. Response: We note that the study population is currently defined under Method heading “Study population” on page 7. We postulate that the use of “study cohort” rather than “study population” may have been confusing. We have changed references to the cohort to “study population”, and we have changed the Study Population section, so it now reads: The study population comprised of people with intellectual disability of ages 18 and over known to NSW disability services who appeared in the DS-MDS, PG, or SDS between 1 Jul 2005 and 30 Jun 2014, with their first appearance being the index date for the study (noting that this allowed some people to have an index date prior to the date they turned 18, as long as they turned 18 between 1 Jul 2005 and 30 Jun 2014). We excluded from the study population people with intellectual disability who did not have any hospital episodes after the index date in our study period. Persons younger than 18 years of age were excluded. 3) Method: The authors have not mentioned the type of this study. Response: The study is a retrospective study, we now mention this explicitly in the methods on page 6. 4) Method: There are no details about the comparison group. Response: This study does not involve a comparison group. All the analysis is done with the aim of predicting the presence or absence of intellectual disability within people who have intellectual disability. We hope that the changes to points 2, 3, 5, and 6 will help clarify the study design. 5) Method: What is the outcome variable? Response: The outcome variable was the presence or absence of an International Classification of Diseases (10th Edition) code for intellectual disability (F7, F84.2, Q90, Q91, Q93, Q95-99. Q86, Q87, Q89.8, P04.3) during an inpatient episode, which is currented detailed in the Methods section under the “Outcome measures” heading on pages 7 & 8. Again, we postulate the use of “outcome measures” rather than “outcome variable” may have been confusing, so we have altered the section for clarity with this in mind. It now reads: Outcome variables We measured our outcome variables at an episode of care level. The episode of care is the period of admitted patient care between a formal (cessation of a stay in hospital) or statistical (cessation of an episode occurring within a hospital stay, which may be followed by another episode) separation, characterised by only one care type.(23–25) Individuals were considered as having the first outcome variable, intellectual disability recognition, if intellectual disability was recorded in a hospital episode as a principal or additional diagnosis. We used the International Classification of Diseases 10th Edition (ICD-10) codes to identify intellectual disability (F7, F84.2, Q90, Q91, Q93, Q95-99. Q86, Q87, Q89.8, P04.3).(22) The second outcome variable was the length of stay in days for a given hospital episode, obtained by the duration in days between episode start and end as recorded in the APDC. Episodes that started and finished within the same day were considered to have a length of stay one day. Episodes that were recorded as occurring within another episode (i.e., ‘nested’ episodes), were included as it could not be determined that these stays did not constitute discrete service contacts. 6) Method: Was each case followed up till the outcome? & 7) Method: Details on statistical analysis are not sufficient. If we followed up the participants till the outcome, should not be the Cox regression more appropriate? Response: All outcome variables are measured at an episode of care level, as opposed to at the person level. That is, we do not follow-up each person until they have an episode of care where they are recognised as having intellectual disability. Rather, we consider all their episodes of care after they enter the study, and examine each episode separately to see whether intellectual disability was recognised in that episode of care or not. We have attempted to clarify this approach under the “Outcome measures” heading in the Methods on page 7 & 8. The section now reads: We measured our outcome variables at an episode of care level. The episode of care is the period of admitted patient care between a formal (cessation of a stay in hospital) or statistical (cessation of an episode occurring within a hospital stay, which may be followed by another episode) separation, characterised by only one care type.[23-25] That is, an episode of care can be thought of as a discrete contact with the hospital inpatient system where a person receives a particular type of care (e.g., mental health care, dialysis, rehabilitation, etc). We included all hospital episodes that occurred for an individual within the follow-up period when determining our outcome variables. Individuals were considered as having the first outcome variable, intellectual disability recognition, if intellectual disability was recorded in a hospital episode as a principal or additional diagnosis. We used the International Classification of Diseases 10th Edition (ICD-10) codes recorded for each hospital episode to identify the presence or absence of intellectual disability in a hospital episode (F7, F84.2, Q90, Q91, Q93, Q95-99. Q86, Q87, Q89.8, P04.3).[22] 8) Result: “intellectual disability was recognized in 19,261 (23.79%) of all episodes”- from what point does the author deduce that? Response: This is drawn from the percentage of episode that had the outcome variable (one of the relevant International Classification of Diseases codes (10th edition)) mentioned in point 5. We have now included a new table (Table 3) on page 16 detailing characteristics of hospital admissions (as suggested by Editor point 2), and moved this point to the “Sociodemographics and episode characteristics” subheading on page 13 9) Discussion: The author thoroughly detailed the result section here. The author gave no perspective or comparison. Response: As in response to Editor point 5) we have now expanded our discussion to contrast with the paper by Bourke et al. on Intellectual Disability Recognition in Children. 10) Discussion: The authors also failed to cite many related articles Response: We have searched again for articles pertaining to predictors of intellectual disability recognition in the health system and found only Bourke et al. to have conducted a study with direct relevance to ours. We acknowledge a small possibility that this could represent a fault in our search method, and as such welcome specific suggestions by the reviewer to literature that we may have missed. We are also happy to expand on specific topics as they relate to our findings at the discretion of the editor. Journal requirements: 1) Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. Response: We have now correctly formatted our documents for PLOS ONE 2) Thank you for stating the following in the Acknowledgments Section of your manuscript: “JT is funded as the Chair of Intellectual Disability Mental Health by the Mental Health Branch of the NSW Ministry of Health.” We note that you have provided additional information within the Acknowledgements Section that is not currently declared in your Funding Statement. Please note that funding information should not appear in the Acknowledgments section or other areas of your manuscript. We will only publish funding information present in the Funding Statement section of the online submission form. Please remove any funding-related text from the manuscript and let us know how you would like to update your Funding Statement. Currently, your Funding Statement reads as follows: “This study was funded by a National Health and Medical Research Council Australia (https://www.nhmrc.gov.au/) funded Partnerships for Better Health grant (APP1056128; Title: Improving the Mental Health Outcomes of People with an Intellectual Disability; Awarded to: JT, EE, RL, LD, KF, AJ, KD) and a National Health and Medical Research Council Australia funded Project grant (APP1123033; Title: Understanding health service system needs for people with intellectual disability; Awarded to: JT, CV, NL, RM, SR). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.” Please include your amended statements within your cover letter; we will change the online submission form on your behalf. Response: This has now been amended, our funding statement now reads: We have amended our funding statement as follows: “This study was funded by a National Health and Medical Research Council Australia (https://www.nhmrc.gov.au/) funded Partnerships for Better Health grant (APP1056128; Title: Improving the Mental Health Outcomes of People with an Intellectual Disability; Awarded to JT) and a National Health and Medical Research Council Australia Project grant (APP1123033; Title: Understanding health service system needs for people with intellectual disability; Awarded to JT). JT is funded as the Chair of Intellectual Disability Mental Health by the Mental Health Branch of the NSW Ministry of Health. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.” 3) In your Data Availability statement, you have not specified where the minimal data set underlying the results described in your manuscript can be found. PLOS defines a study's minimal data set as the underlying data used to reach the conclusions drawn in the manuscript and any additional data required to replicate the reported study findings in their entirety. All PLOS journals require that the minimal data set be made fully available. For more information about our data policy, please see http://journals.plos.org/plosone/s/data-availability. Upon re-submitting your revised manuscript, please upload your study’s minimal underlying data set as either Supporting Information files or to a stable, public repository and include the relevant URLs, DOIs, or accession numbers within your revised cover letter. For a list of acceptable repositories, please see http://journals.plos.org/plosone/s/data-availability#loc-recommended-repositories. Any potentially identifying patient information must be fully anonymized. Important: If there are ethical or legal restrictions to sharing your data publicly, please explain these restrictions in detail. Please see our guidelines for more information on what we consider unacceptable restrictions to publicly sharing data: http://journals.plos.org/plosone/s/data-availability#loc-unacceptable-data-access-restrictions. Note that it is not acceptable for the authors to be the sole named individuals responsible for ensuring data access. We will update your Data Availability statement to reflect the information you provide in your cover letter. Response: The nature of our data means that we cannot share the data publicly. We have amended our data statement to read: Our datasets cannot be shared publicly due to the data usage agreement between the Department of Developmental Disability Neuropsychiatry, The University of New South Wales Sydney, and the data custodians who provide access to our data. Researchers who meet the criteria for obtaining access to confidential data who wish to access the data should enquire to the NSW Population and Health Services Research Ethics Committee (cinsw-ethics@health.nsw.gov.au) and quote the project and sub-study reference number (2013/02/446, 2019UMB0209). 4) Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice. Response: This has been completed Submitted filename: Response to Reviewers.docx Click here for additional data file. 7 Mar 2022
PONE-D-21-32313R1
Predictors and outcomes of recognition of intellectual disability for adults during hospital admissions: A retrospective data linkage study in NSW, Australia
PLOS ONE Dear Dr. Trollor, Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process. Please submit your revised manuscript by Apr 21 2022 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file. Please include the following items when submitting your revised manuscript:
A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'. A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'. An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'. If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter. If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: https://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols. Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols. We look forward to receiving your revised manuscript. Kind regards, Rashidul Alam Mahumud, MPH, MSc, PhD Academic Editor PLOS ONE Journal Requirements: Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice. [Note: HTML markup is below. Please do not edit.] Reviewers' comments: Reviewer's Responses to Questions Comments to the Author 1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation. Reviewer #2: (No Response) ********** 2. Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented. Reviewer #2: Yes ********** 3. Has the statistical analysis been performed appropriately and rigorously? Reviewer #2: Yes ********** 4. Have the authors made all data underlying the findings in their manuscript fully available? The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified. Reviewer #2: Yes ********** 5. Is the manuscript presented in an intelligible fashion and written in standard English? PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here. Reviewer #2: Yes ********** 6. Review Comments to the Author Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters) Reviewer #2: The article entitled “Predictors and outcomes of recognition of intellectual disability for adults during hospital admissions: A retrospective data linkage study in NSW, Australia” is representing the factors and outcome associated with the intellectual disability for adults during hospital admissions. The overall manuscript (MS) sounds good, well represented, and described. I think it will contribute more for the aged people related research. I would like to take attention of the authors to address/explain the following concerns for updating the MS before publication: (i) The intellectual disability basically develops at the young age which may affect the next ages. I am not sure that the participants (especially the elders) were asked whether they were developed a confirmed ID syndrome in their early stages of life (any medical confirmation about that??). Author should clear these although they mentioned autism spectrum disorder (ASD) which is a developmental disability that can cause significant social, communication and behavioral challenges. (ii) Another point is that the elderly people are more likely to develop Dementia/Alzheimer disease. I would like to request to add this type of description whether the participants had their diagnosis of Dementia/Alzheimer disease before?? Although the participants were asked about mental disorder. ********** 7. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files. If you choose “no”, your identity will remain anonymous but your review may still be made public. Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy. Reviewer #2: No [NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.] While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.
Submitted filename: Reviewer comment.docx Click here for additional data file. 10 Mar 2022 1) The intellectual disability basically develops at the young age which may affect the next ages. I am not sure that the participants (especially the elders) were asked whether they were developed a confirmed ID syndrome in their early stages of life (any medical confirmation about that??). Author should clear these although they mentioned autism spectrum disorder (ASD) which is a developmental disability that can cause significant social, communication and behavioral challenges. Answer: Our project did not involve the collection of data directly from participants through interviews – all the data used in the project was acquired via administrative datasets (which included all relevant diagnostic flags, including those for intellectual disability and autism spectrum disorder). We have attempted to clarify this point in our Methods section on page 6, where we have added the following section in italics to paragraph 1: “This study was a retrospective cohort study, conducted as a substudy within a bigger data linkage infrastructure project described in Reppermund et al.[22] All data used in this study were collected into administrative datasets during the interaction of members of the cohort with administrative services (e.g., hospital or disability services). No participant data were gained through direct interaction with members of the cohort, such as via structured interviews. Linkage was performed by the NSW Centre for Health Record Linkage using best practice methods.” 2) Another point is that the elderly people are more likely to develop Dementia/Alzheimer disease. I would like to request to add this type of description whether the participants had their diagnosis of Dementia/Alzheimer disease before?? Although the participants were asked about mental disorder. Answer: We have carefully considered this point, and based on the combined experience of the team in both the study of intellectual disability and dementia, believe that the addition of a discussion around dementia would not be relevant to the current paper. Our reasoning is that dementia and intellectual disability represent different groups of disorders, and based on experience with dementia and intellectual disability in other projects, we believe dementia would not present a confounding factor to the recognition of intellectual disability in hospital settings. Submitted filename: Response to Reviewers.docx Click here for additional data file. 14 Mar 2022 Predictors and outcomes of recognition of intellectual disability for adults during hospital admissions: A retrospective data linkage study in NSW, Australia PONE-D-21-32313R2 Dear Dr. Trollor, We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements. Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication. An invoice for payment will follow shortly after the formal acceptance. To ensure an efficient process, please log into Editorial Manager at http://www.editorialmanager.com/pone/, click the 'Update My Information' link at the top of the page, and double check that your user information is up-to-date. If you have any billing related questions, please contact our Author Billing department directly at authorbilling@plos.org. If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org. Kind regards, Rashidul Alam Mahumud, MPH, MSc, PhD Academic Editor PLOS ONE Additional Editor Comments (optional): Reviewers' comments: 16 Mar 2022 PONE-D-21-32313R2 Predictors and outcomes of recognition of intellectual disability for adults during hospital admissions: A retrospective data linkage study in NSW, Australia Dear Dr. Trollor: I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department. If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org. If we can help with anything else, please email us at plosone@plos.org. Thank you for submitting your work to PLOS ONE and supporting open access. Kind regards, PLOS ONE Editorial Office Staff on behalf of Dr. Rashidul Alam Mahumud Academic Editor PLOS ONE
  18 in total

1.  Learning Disability Liaison Nursing Services in south-east Scotland: a mixed-methods impact and outcome study.

Authors:  M Brown; J MacArthur; A McKechanie; S Mack; M Hayes; J Fletcher
Journal:  J Intellect Disabil Res       Date:  2011-12-06

2.  Implementing reasonable adjustments for -disabled people in healthcare services.

Authors:  Pauline Heslop; Sue Turner; Stuart Read; Julie Tucker; Steve Seaton; Brian Evans
Journal:  Nurs Stand       Date:  2019-07-26

3.  Preventable Emergency Hospital Admissions Among Adults With Intellectual Disability in England.

Authors:  Fay J Hosking; Iain M Carey; Stephen DeWilde; Tess Harris; Carole Beighton; Derek G Cook
Journal:  Ann Fam Med       Date:  2017-09       Impact factor: 5.166

4.  Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data.

Authors:  Hude Quan; Vijaya Sundararajan; Patricia Halfon; Andrew Fong; Bernard Burnand; Jean-Christophe Luthi; L Duncan Saunders; Cynthia A Beck; Thomas E Feasby; William A Ghali
Journal:  Med Care       Date:  2005-11       Impact factor: 2.983

5.  Epidemiology of autism in adults across age groups and ability levels.

Authors:  Traolach S Brugha; Nicola Spiers; John Bankart; Sally-Ann Cooper; Sally McManus; Fiona J Scott; Jane Smith; Freya Tyrer
Journal:  Br J Psychiatry       Date:  2016-07-07       Impact factor: 9.319

6.  Potentially preventable hospitalisations of people with intellectual disability in New South Wales.

Authors:  Janelle C Weise; Preeyaporn Srasuebkul; Julian N Trollor
Journal:  Med J Aust       Date:  2021-05-24       Impact factor: 7.738

7.  Health characteristics and consultation patterns of people with intellectual disability: a cross-sectional database study in English general practice.

Authors:  Iain M Carey; Sunil M Shah; Fay J Hosking; Stephen DeWilde; Tess Harris; Carole Beighton; Derek G Cook
Journal:  Br J Gen Pract       Date:  2016-02-23       Impact factor: 5.386

8.  Cause of death and potentially avoidable deaths in Australian adults with intellectual disability using retrospective linked data.

Authors:  Julian Trollor; Preeyaporn Srasuebkul; Han Xu; Sophie Howlett
Journal:  BMJ Open       Date:  2017-02-07       Impact factor: 2.692

9.  Health and wellbeing of people with intellectual disability in New South Wales, Australia: a data linkage cohort.

Authors:  Simone Reppermund; Theresa Heintze; Preeyaporn Srasuebkul; Rebecca Reeve; Kimberlie Dean; Melinda Smith; Eric Emerson; Phillip Snoyman; Eileen Baldry; Leanne Dowse; Tracey Szanto; Grant Sara; Tony Florio; Anina Johnson; Melissa Clements; Kathryn McKenzie; Julian Trollor
Journal:  BMJ Open       Date:  2019-09-30       Impact factor: 2.692

10.  The barriers to and enablers of providing reasonably adjusted health services to people with intellectual disabilities in acute hospitals: evidence from a mixed-methods study.

Authors:  Irene Tuffrey-Wijne; Lucy Goulding; Nikoletta Giatras; Elisabeth Abraham; Steve Gillard; Sarah White; Christine Edwards; Sheila Hollins
Journal:  BMJ Open       Date:  2014-04-16       Impact factor: 2.692

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