Literature DB >> 3532631

The susceptibility of Cryptococcus neoformans to an antimycotic agent (G2) from alfalfa.

I Polacheck, U Zehavi, M Naim, M Levy, R Evron.   

Abstract

Compound G2, 2-beta-hydroxy-3-beta-O-(beta-D-glucopyranosyl)-delta 12-oleanene-23,28-dionic acid, isolated from alfalfa roots, demonstrated considerable activity against Cryptococcus neoformans (MIC value of 2 micrograms/ml). Compound G2 exhibited rapid killing of this fungus (MFC value of 4 micrograms/ml) suggesting that it might be a useful active agent in the treatment of cryptococcosis.

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Year:  1986        PMID: 3532631     DOI: 10.1016/s0176-6724(86)80080-3

Source DB:  PubMed          Journal:  Zentralbl Bakteriol Mikrobiol Hyg A        ISSN: 0176-6724


  2 in total

1.  Activity of compound G2 isolated from alfalfa roots in experimental dermatophyte infection.

Authors:  R Evron; M Guizie; U Zehavi; I Polacheck
Journal:  Antimicrob Agents Chemother       Date:  1990-08       Impact factor: 5.191

2.  Activities of compound G2 isolated from alfalfa roots against dermatophytes.

Authors:  R Evron; I Polacheck; M Guizie; M Levy; U Zehavi
Journal:  Antimicrob Agents Chemother       Date:  1988-10       Impact factor: 5.191

  2 in total

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