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Literature DB >> 35322174

TCR-pMHC: Envisioning the specialized dynamics of the target 5-component complex.

Joseph S Murray¹.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2022 PMID： 35322174 PMCID： PMC9151814 DOI： 10.1038/s41423-022-00856-3

Source DB: PubMed Journal: Cell Mol Immunol ISSN： 1672-7681 Impact factor: 22.096

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References

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12 in total

1. The alphabeta T cell receptor is an anisotropic mechanosensor.

Authors: Sun Taek Kim; Koh Takeuchi; Zhen-Yu J Sun; Maki Touma; Carlos E Castro; Amr Fahmy; Matthew J Lang; Gerhard Wagner; Ellis L Reinherz
Journal: J Biol Chem Date: 2009-09-15 Impact factor: 5.157

2. How drag sharpens a T cell's view on antigen.

Authors: Gerhard J Schütz; Johannes B Huppa
Journal: Proc Natl Acad Sci U S A Date: 2019-08-01 Impact factor: 11.205

3. TCR-pMHC kinetics under force in a cell-free system show no intrinsic catch bond, but a minimal encounter duration before binding.

Authors: Laurent Limozin; Marcus Bridge; Pierre Bongrand; Omer Dushek; Philip Anton van der Merwe; Philippe Robert
Journal: Proc Natl Acad Sci U S A Date: 2019-07-17 Impact factor: 11.205

4. Assessing the native state conformational distribution of ubiquitin by peptide acidity.

Authors: Griselda Hernández; Janet S Anderson; David M LeMaster
Journal: Biophys Chem Date: 2010-10-15 Impact factor: 2.352

5. The αβTCR mechanosensor exploits dynamic ectodomain allostery to optimize its ligand recognition site.

Authors: Wonmuk Hwang; Robert J Mallis; Matthew J Lang; Ellis L Reinherz
Journal: Proc Natl Acad Sci U S A Date: 2020-08-13 Impact factor: 11.205

6. NMR: an essential structural tool for integrative studies of T cell development, pMHC ligand recognition and TCR mechanobiology.

Authors: Robert J Mallis; Kristine N Brazin; Jonathan S Duke-Cohan; Wonmuk Hwang; Jia-Huai Wang; Gerhard Wagner; Haribabu Arthanari; Matthew J Lang; Ellis L Reinherz
Journal: J Biomol NMR Date: 2019-02-27 Impact factor: 2.835

TCR-pMHC: Envisioning the specialized dynamics of the target 5-component complex.

1. The alphabeta T cell receptor is an anisotropic mechanosensor.

2. How drag sharpens a T cell's view on antigen.

3. TCR-pMHC kinetics under force in a cell-free system show no intrinsic catch bond, but a minimal encounter duration before binding.

4. Assessing the native state conformational distribution of ubiquitin by peptide acidity.

5. The αβTCR mechanosensor exploits dynamic ectodomain allostery to optimize its ligand recognition site.

6. NMR: an essential structural tool for integrative studies of T cell development, pMHC ligand recognition and TCR mechanobiology.

7. CDR3 binding chemistry controls TCR V-domain rotational probability and germline CDR2 scanning of polymorphic MHC.

8. The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.

Review 9. An old Twist in HLA-A: CDR3α Hook up at an R65-joint.

10. Direct evidence for conformational dynamics in major histocompatibility complex class I molecules.