| Literature DB >> 35320548 |
Sophia Borowski1,2, Nancy Freitag1,2,3, Iris Urban4, Geert Michel4, Gabriela Barrientos5, Sandra M Blois6.
Abstract
Galectin-1 (gal-1), a member of a family of evolutionarily conserved glycan-binding proteins, is differentially expressed at the feto-maternal interface and appears to be functionally polyvalent, with a wide range of biological activities. However, the contributions of maternal and/or feto-placental gal-1 to the signaling networks promoting a healthy pregnancy are still being elucidated. This chapter discusses the methods commonly employed to study the maternal or feto-placental contribution of gal-1 during pregnancy in mice. The methods described here can be used to decipher the specific role of each source, e.g., maternal and/or feto-placental derived gal-1 in the orchestration of pregnancy-associated processes.Entities:
Keywords: Galectin-1; In vitro fertilization; Lectin staining; Maternal and placental galectin-1 models; Pregnancy outcome
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Year: 2022 PMID： 35320548 DOI： 10.1007/978-1-0716-2055-7_32
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745