Literature DB >> 3531909

Periventricular hypothalamic cells in the rat brain contain insulin mRNA.

W S Young.   

Abstract

In situ hybridization histochemistry with a 35S-labeled oligodeoxyribonucleotide probe for insulin was performed in the rat. Labeled cells were observed in the pancreas and in the periventricular nucleus of the hypothalamus. No labeling was seen elsewhere in the brain, including the olfactory bulb, the choroid plexus, and the tissue adjacent to the lateral ventricles. This finding suggests that insulin may be released from cells in the periventricular nucleus for transport via cerebrospinal fluid to other brain regions.

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Year:  1986        PMID: 3531909     DOI: 10.1016/0143-4179(86)90035-1

Source DB:  PubMed          Journal:  Neuropeptides        ISSN: 0143-4179            Impact factor:   3.286


  27 in total

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Review 2.  Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease?

Authors:  Sónia C Correia; Renato X Santos; George Perry; Xiongwei Zhu; Paula I Moreira; Mark A Smith
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Review 3.  Bidirectional metabolic regulation of neurocognitive function.

Authors:  Alexis M Stranahan; Mark P Mattson
Journal:  Neurobiol Learn Mem       Date:  2011-01-12       Impact factor: 2.877

Review 4.  Brain insulin: regulation, mechanisms of action and functions.

Authors:  Kyriaki Gerozissis; Gerozissis Kyriaki
Journal:  Cell Mol Neurobiol       Date:  2003-02       Impact factor: 5.046

Review 5.  Insulin and insulin-like growth factor receptors in the nervous system.

Authors:  M Adamo; M K Raizada; D LeRoith
Journal:  Mol Neurobiol       Date:  1989 Spring-Summer       Impact factor: 5.590

6.  Insulin synthesis in chick embryo retinas during development.

Authors:  G Tesoriere; G Calvaruso; R Vento; M Giuliano; M Lauricella; M Carabillò
Journal:  Neurochem Res       Date:  1994-07       Impact factor: 3.996

Review 7.  Neurotrophic factors for the investigation and treatment of movement disorders.

Authors:  Justo Garcia De Yébenes; Marina Sánchez; Maria Angeles Mena
Journal:  Neurotox Res       Date:  2003       Impact factor: 3.911

Review 8.  Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums.

Authors:  Steven E Arnold; Zoe Arvanitakis; Shannon L Macauley-Rambach; Aaron M Koenig; Hoau-Yan Wang; Rexford S Ahima; Suzanne Craft; Sam Gandy; Christoph Buettner; Luke E Stoeckel; David M Holtzman; David M Nathan
Journal:  Nat Rev Neurol       Date:  2018-01-29       Impact factor: 42.937

Review 9.  Brain insulin dysregulation: implication for neurological and neuropsychiatric disorders.

Authors:  Rasoul Ghasemi; Leila Dargahi; Ali Haeri; Maryam Moosavi; Zahurin Mohamed; Abolhassan Ahmadiani
Journal:  Mol Neurobiol       Date:  2013-01-20       Impact factor: 5.590

10.  Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type.

Authors:  S Hoyer; R Nitsch
Journal:  J Neural Transm       Date:  1989       Impact factor: 3.575

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