Literature DB >> 35314856

Severe Acute Respiratory Syndrome Coronavirus 2 Adaptive Immunity in Nursing Home Residents Following a Third Dose of the Comirnaty Coronavirus Disease 2019 Vaccine.

Estela Giménez1, Eliseo Albert1, Joao Zulaica2, Ignacio Torres1, Luciana Rusu2, Alicia Rodríguez Moreno2, Javier S Burgos3, Salvador Peiró4, Dolores Salas4,5, Hermelinda Vanaclocha5, Ramón Limón6, María Jesús Alcaraz1, José Sánchez-Payá7,8, Javier Díez-Domingo4, Iñaki Comas9,10, Fernando Gonzáles-Candelas2,10, Ron Geller2, David Navarro1,11.   

Abstract

A third Comirnaty vaccine dose increased severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain antibody levels (median, 93-fold) and neutralizing antibody titers against Wuhan-Hu-1 (median, 57-fold), Beta (me 22-fold), Delta, (median, 43-fold), and Omicron (median, 8-fold) variants, but had less impact on S-reactive T-cell immunity in nursing home residents.
© The Author(s) 2022. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  Comirnaty COVID-19 vaccine third dose; SARS-CoV-2-S T cells; SARS-CoV-2-S antibodies; neutralizing antibodies; nursing home residents

Mesh：

Substances：

Year:  2022        PMID： 35314856      PMCID： PMC9129117          DOI： 10.1093/cid/ciac223

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   20.999


  2 in total

Review 1.  Alicante-Winter Immunology Symposium in Health (A-Wish) and the Boulle-SEI awards: A collaboration between the Spanish Society for immunology, the University of Alicante and the Jean Boulle Group to honor the Balmis Expedition.

Authors:  Jordi Ochando; Carmen Camara; Leighton Durham; Jose Miguel Sempere; Marcos Lopez-Hoyos
Journal:  Curr Res Immunol       Date:  2022-06-18

2.  SARS-CoV-2 Omicron BA.1 variant breakthrough infections in nursing home residents after an homologous third dose of the Comirnaty® COVID-19 vaccine: Looking for correlates of protection.

Authors:  Ignacio Torres; Estela Giménez; Eliseo Albert; Joao Zulaica; Beatriz Álvarez-Rodríguez; Javier S Burgos; Salvador Peiró; Ramón Limón; Hermelinda Vanaclocha; Celia Rodado; Pilar Botija; Amelia Sifre; Borja Tur; Rosa Andrés Lozano; Iria Orosa; MªÁngeles Vicente-Ruiz; Ramón J Carrión; Maria Á Clari; José Sánchez-Payá; Javier Díez-Domingo; Iñaki Comas; Fernando González-Candelas; Ron Geller; David Navarro
Journal:  J Med Virol       Date:  2022-05-25       Impact factor: 20.693
  2 in total

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