| Literature DB >> 35313856 |
Yi Liu1, Meng-Shan Tan2, Zuo-Teng Wang1, Wei Xu1, Lan Tan3.
Abstract
Entities:
Year: 2022 PMID: 35313856 PMCID: PMC8935798 DOI: 10.1186/s12883-022-02616-2
Source DB: PubMed Journal: BMC Neurol ISSN: 1471-2377 Impact factor: 2.474
Fig. 2The relationship between Caspase-1 rs554344 and CSF t-tau levels was mediated by CSF p-tau. The total effect of Caspase-1 rs554344 on CSF t-tau was estimated and was divided into direct effect and the mediated effect through CSF p-tau. The mediation analysis showed that CSF p-tau significantly and partially mediated the association between Caspase-1 variant and CSF t-tau levels, accounting for 80% of the total effect