Literature DB >> 3531019

Polyclonal response of human lymphocytes to Chlamydia trachomatis.

L Räsänen, M Lehtinen, M Lehto, J Paavonen, P Leinikki.   

Abstract

The mitogenicity of Chlamydia trachomatis was investigated. Umbilical cord blood cells from healthy newborns were used. These cells were stimulated in cultures with partially purified C. trachomatis elementary bodies. Proliferation of cultured lymphocytes and secreted immunoglobulins and leukocyte migration inhibitory factor were measured in the culture supernatants. Our results showed that C. trachomatis is able to elicit polyclonal antibody, lymphokine, and DNA synthesis.

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Year:  1986        PMID： 3531019      PMCID： PMC260111          DOI： 10.1128/iai.54.1.28-31.1986

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  21 in total

1.  Selective triggering of B cell subpopulations by mitogens.

Authors:  E Gronowicz; A Coutinho
Journal:  Eur J Immunol       Date:  1974-11       Impact factor: 5.532

2.  Potentation by fluorodeoxyuridine of 125I-deoxyuridine uptake by human and chicken lymphocytes in the quantitation of mitogenic response.

Authors:  T Asantila; P Toivanen
Journal:  J Immunol Methods       Date:  1974-12       Impact factor: 2.303

3.  Auto-immune serum factors and IgA elevation in lymphogranuloma venereum.

Authors:  A Lassus; K K Mustakallio; O Wager
Journal:  Ann Clin Res       Date:  1970-03

4.  Cytochemical identification of monocytes and granulocytes.

Authors:  L T Yam; C Y Li; W H Crosby
Journal:  Am J Clin Pathol       Date:  1971-03       Impact factor: 2.493

5.  Chlamydia trachomatis stimulates human peripheral blood B lymphocytes to proliferate and secrete polyclonal immunoglobulins in vitro.

Authors:  J Bard; D Levitt
Journal:  Infect Immun       Date:  1984-01       Impact factor: 3.441

6.  Bacteria induce lymphokine synthesis polyclonally in human B lymphocytes.

Authors:  L Räsänen; E Karhumäki; H Arvilommi
Journal:  J Immunol       Date:  1978-08       Impact factor: 5.422

7.  Chlamydial endometritis. A histological and immunohistochemical analysis.

Authors:  B Winkler; W Reumann; M Mitao; L Gallo; R M Richart; C P Crum
Journal:  Am J Surg Pathol       Date:  1984-10       Impact factor: 6.394

8.  Respiratory-tract colonization and a distinctive pneumonia syndrome in infants infected with Chlamydia trachomatis.

Authors:  M O Beem; E M Saxon
Journal:  N Engl J Med       Date:  1977-02-10       Impact factor: 91.245

9.  Chlamydia trachomatis (L2 serovar) binds to distinct subpopulations of human peripheral blood leukocytes.

Authors:  J Bard; D Levitt
Journal:  Clin Immunol Immunopathol       Date:  1986-02

10.  Proliferative human T cell responses to Chlamydia trachomatis in vitro.

Authors:  E Qvigstad; K Skaug; E Thorsby
Journal:  Acta Pathol Microbiol Immunol Scand C       Date:  1983-06
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  3 in total

Review 1.  Pathogenesis of pelvic inflammatory disease.

Authors:  L Weström; P Wölner-Hanssen
Journal:  Genitourin Med       Date:  1993-02

2.  Analysis of DNA synthesis in herpes simplex virus infected cells by dual parameter flow cytometry.

Authors:  M Lehtinen; P Kulomaa; O P Kallioniemi; J Paavonen; P Leinikki
Journal:  Arch Virol       Date:  1989       Impact factor: 2.574

3.  Immunopathogenesis of chlamydial pelvic inflammatory disease: the role of heat-shock proteins.

Authors:  J Paavonen; M Lehtinen
Journal:  Infect Dis Obstet Gynecol       Date:  1994
  3 in total

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