Literature DB >> 35308681

Management of an Unusual Metastasis of Cervical Cancer in the Adrenal Bed With Stereotactic Ablative Body Radiation Therapy.

Raul Puente-Vallejo1,2,3, Pamela Ochoa1,3, Cristina Núñez2, Luis De Los Reyes2.   

Abstract

Uterine cervical carcinoma is an important type of cancer among Ecuadorian women, especially in adult women. Survival rates have improved with the development of radiotherapy, surgical techniques, and chemotherapy. However, recurrence and/or metastasis are not unusual phenomena. Frequent sites of metastasis are the lungs, regional lymph nodes, and bones. Atypical locations can also occur on solid organs, such as adrenal glands. Treatment for the rare complication that is adrenal metastasis is individualized, it can include surgical resection, chemotherapy, local ablation, or different types of radiotherapy. We aimed to report a case of an Ecuadorian woman from Quito city with a diagnosis of cervical carcinoma diagnosed in 2009, treated surgically and with adjuvant chemotherapy. Her progression was monitored with medical controls with no recurrence until 2018, when she relapsed with a metastatic invasion of the pelvic ganglia and the surroundings of the abdominal aorta, with a histopathologic diagnosis of adenocarcinoma. She was then treated with chemotherapy and radiotherapy until June 2019. In 2020, she went through a splenectomy and left adrenalectomy to treat vascular thrombosis. In 2021, 37 x 15 mm mass was discovered in the surgical bed of the previously removed adrenal gland. It was treated as an oligometastatic carcinoma with stereotactic body radiotherapy (SBRT) by a linear accelerator.
Copyright © 2022, Puente-Vallejo et al.

Entities:  

Keywords:  ablative therapy; adrenal bed metastases; cervical cancer; sabrt; vmat

Year:  2022        PMID: 35308681      PMCID: PMC8923247          DOI: 10.7759/cureus.22178

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  17 in total

Review 1.  Neoplastic metastases to the endocrine glands.

Authors:  Anna Angelousi; Krystallenia I Alexandraki; George Kyriakopoulos; Marina Tsoli; Dimitrios Thomas; Gregory Kaltsas; Ashley Grossman
Journal:  Endocr Relat Cancer       Date:  2020-01       Impact factor: 5.678

2.  Stereotactic Body Radiation Therapy of Adrenal Metastases: A Pooled Meta-Analysis and Systematic Review of 39 Studies with 1006 Patients.

Authors:  William C Chen; Joe D Baal; Ulysis Baal; Jonathan Pai; Alexander Gottschalk; Lauren Boreta; Steve E Braunstein; David R Raleigh
Journal:  Int J Radiat Oncol Biol Phys       Date:  2020-01-27       Impact factor: 7.038

3.  Survival outcomes following adrenalectomy for isolated metastases to the adrenal gland.

Authors:  Jason Ramsingh; Patrick O'Dwyer; Carol Watson
Journal:  Eur J Surg Oncol       Date:  2019-01-04       Impact factor: 4.424

Review 4.  Surgical and ablative therapies for the management of adrenal 'oligometastases' - A systematic review.

Authors:  Ashray Gunjur; Cuong Duong; David Ball; Shankar Siva
Journal:  Cancer Treat Rev       Date:  2014-04-16       Impact factor: 12.111

5.  Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.

Authors:  Hyuna Sung; Jacques Ferlay; Rebecca L Siegel; Mathieu Laversanne; Isabelle Soerjomataram; Ahmedin Jemal; Freddie Bray
Journal:  CA Cancer J Clin       Date:  2021-02-04       Impact factor: 508.702

6.  Survival and prognostic factors of pulmonary oligometastases treated with stereotactic body radiotherapy.

Authors:  Aman Sharma; Marloes Duijm; Esther Oomen-de Hoop; Joachim G Aerts; Cornelis Verhoef; Mischa Hoogeman; Joost Jan Nuyttens
Journal:  Acta Oncol       Date:  2018-10-03       Impact factor: 4.089

Review 7.  Advances in diagnosis and treatment of metastatic cervical cancer.

Authors:  Haoran Li; Xiaohua Wu; Xi Cheng
Journal:  J Gynecol Oncol       Date:  2016-07       Impact factor: 4.401

8.  Stereotactic radiosurgery and stereotactic body radiation therapy cost-effectiveness results.

Authors:  Akash Bijlani; Giovanni Aguzzi; David W Schaal; Pantaleo Romanelli
Journal:  Front Oncol       Date:  2013-04-08       Impact factor: 6.244

9.  SBRT to adrenal metastases provides high local control with minimal toxicity.

Authors:  Kristin Plichta; Nathan Camden; Muhammed Furqan; Taher Abu Hejleh; Gerald H Clamon; Jun Zhang; Ryan T Flynn; Sudershan K Bhatia; Mark C Smith; John M Buatti; Bryan G Allen
Journal:  Adv Radiat Oncol       Date:  2017-08-04

10.  Radiosurgery and fractionated stereotactic body radiotherapy for patients with lung oligometastases.

Authors:  Goda G Kalinauskaite; Ingeborg I Tinhofer; Markus M Kufeld; Anne A Kluge; Arne A Grün; Volker V Budach; Carolin C Senger; Carmen C Stromberger
Journal:  BMC Cancer       Date:  2020-05-11       Impact factor: 4.430

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