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Literature DB >> 353080

Lysosomal enzyme cytochemistry of blood neutrophils.

J T Wozniak, T L Orchard, P H Mackie, D K Mistry, J Stuart.

Abstract

Patients with bacterial infection may show altered membrane permeability of the primary azurophilic lysosomes of blood neutrophils. A new enzyme cytochemical technique, sensitive to increased membrane permeability caused by contact of neutrophils with acetone, saponin, low pH, Streptolysin O, bacteria, and nylon wool, has been developed. The method is of potential value as a screening test for bacterial infection and for detecting neutrophil damage during filtration leucopheresis.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1978 PMID： 353080 PMCID： PMC1145368 DOI： 10.1136/jcp.31.7.648

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

20 in total

1. Cytochemical demonstration and measurement of leucocyte alkaline phosphatase activity in normal and pathological states by a modified azo-dye coupling technique.

Authors: F G HAYHOE; D QUAGLINO
Journal: Br J Haematol Date: 1958-10 Impact factor: 6.998

2. The nitroblue tetrazolium reduction test versus conventional hematology in the diagnosis of bacterial infection.

Authors: R T Steigbigel; P K Johnson; J S Remington
Journal: N Engl J Med Date: 1974-01-31 Impact factor: 91.245

3. Nitroblue-tetrazolium tests.

Authors: A W Segal
Journal: Lancet Date: 1974-11-23 Impact factor: 79.321

4. N.B.T. test stimulated.

Authors: H H Park; R A Good
Journal: Lancet Date: 1970-09-19 Impact factor: 79.321

5. Human toxic neutrophils. 3. Metabolic characteristics.

Authors: C E McCall; L R DeChatelet; M R Cooper; C Shannon
Journal: J Infect Dis Date: 1973-01 Impact factor: 5.226

6. Evidence for altered lysosomal membranes in synovial lining cells from human rheumatoid joints.

Authors: J Chayen; L Bitensky; R G Butcher; B Cashman
Journal: Beitr Pathol Date: 1971-02

7. The cytocentrifuge NBT test.

Authors: P A Gordon; J Stuart; T R Lee; G R Breeze; R N Pugh
Journal: J Clin Pathol Date: 1975-08 Impact factor: 3.411

8. Sequential degranulation of the two types of polymorphonuclear leukocyte granules during phagocytosis of microorganisms.

Authors: D F Bainton
Journal: J Cell Biol Date: 1973-08 Impact factor: 10.539

Lysosomal enzyme cytochemistry of blood neutrophils.

1. Cytochemical demonstration and measurement of leucocyte alkaline phosphatase activity in normal and pathological states by a modified azo-dye coupling technique.

2. The nitroblue tetrazolium reduction test versus conventional hematology in the diagnosis of bacterial infection.

3. Nitroblue-tetrazolium tests.

4. N.B.T. test stimulated.

5. Human toxic neutrophils. 3. Metabolic characteristics.

6. Evidence for altered lysosomal membranes in synovial lining cells from human rheumatoid joints.

7. The cytocentrifuge NBT test.

8. Sequential degranulation of the two types of polymorphonuclear leukocyte granules during phagocytosis of microorganisms.

9. The development of neutrophilic polymorphonuclear leukocytes in human bone marrow.

10. Lysosomal and ultrastructural changes in human "toxic" neutrophils during bacterial infection.

1. Bronchogenic carcinoma, leukemoid reaction, marantic endocarditis, and consumptive thrombocytopathy.

2. Neutrophil cytochemistry in bacterial infection.