Literature DB >> 35306934

Development and validation of a risk score for prediction of clinical success after duodenal stenting for malignant gastric outlet obstruction.

Maria Cristina Conti Bellocchi1, Stefano Francesco Crinò1, Marzia Fioravante1, Enrico Maria Gabrieletto1, Serena Di Stefano1, Laura Bernardoni1, Paraskevas Gkolfakis2, Andrew Ofosu3, Antonio Facciorusso1,4, Armando Gabbrielli1.   

Abstract

BACKGROUND: To develop and validate a risk score for predicting clinical success after duodenal stenting using self-expanding metallic stents (SEMS) for malignant gastric outlet obstruction (GOO). RESEARCH DESIGN AND METHODS: Consecutive patients who underwent duodenal stenting for malignant GOO were evaluated. Potential predictors of clinical success were determined by uni/multivariate logistic regression analysis.Multiplication of the regression coefficients of the logistic regression model by a factor of two and rounding to obtain easy-to-use point numbers enabling the calculation of the score. Using 10-fold cross-validation, the model was internally validated.
RESULTS: One hundred twelve patients were included. Clinical success was achieved in 93 (83.0%) patients. On multivariate logistic regression, selected age ≤65 years (p = 0.05, 1.5 points), stenosis type I (p = 0.04, 3 points), and pancreatic cancer (p = 0.01, 3.5 points) were significant predictors of clinical success. On the Receiver Operating Characteristic (ROC) analysis, a score of 5 had higher specificity and sensitivity.
CONCLUSION: Our score could be useful at identifying, among poor surgical candidates, patients more likely to benefit from SEMS.

Entities:  

Keywords:  EUS-guided gastroenterostomy; gastric cancer; gastric outlet obstruction; pancreatic cancer; self-expandable metal stent

Mesh:

Year:  2022        PMID: 35306934     DOI: 10.1080/17474124.2022.2056445

Source DB:  PubMed          Journal:  Expert Rev Gastroenterol Hepatol        ISSN: 1747-4124            Impact factor:   3.869


  1 in total

Review 1.  How to successfully administer palliative treatment with a stent for malignant gastric outlet obstruction?

Authors:  Iruru Maetani
Journal:  Front Med (Lausanne)       Date:  2022-08-09
  1 in total

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