Literature DB >> 3530141

Serine proteinases in human cutaneous mastocytosis.

J E Fräki, N M Schechter, G S Lazarus.   

Abstract

The main chymotryptic and tryptic proteinases of human skin were found in high-salt extracts of human dermis. The levels of these enzymes were markedly increased in salt extracts of human cutaneous mastocytosis as compared to the levels found in extracts of involved skin from the same patients, human cutaneous hemangiomas, and normal human skin. These data suggest that the chymotryptic and tryptic proteinases of human skin are primarily of mast-cell origin.

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Year:  1986        PMID： 3530141     DOI： 10.1007/bf00418163

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN： 0340-3696            Impact factor:   3.017


  12 in total

1.  The main neutral protease of rat skin is a mast cell enzyme. Immunohistochemical localization of the enzyme in rat skin with the peroxidase-antiperoxidase (PAP) complex method.

Authors:  H E Seppä; M Järvinen
Journal:  Acta Histochem       Date:  1979       Impact factor: 2.479

2.  A modified bromosulfalein assay for the quantitative estimation of protein.

Authors:  J McGuire; P Taylor; L A Greene
Journal:  Anal Biochem       Date:  1977-11       Impact factor: 3.365

3.  Human skin proteases. Separation and characterization of two acid proteases resembling cathepsin B1 and cathepsin D and of an inhibitor of cathepsin B1.

Authors:  J E Fräki
Journal:  Arch Dermatol Res       Date:  1976-06-21       Impact factor: 3.017

4.  Rat skin main neutral protease: purification and properties.

Authors:  H E Seppä; M Järvinen
Journal:  J Invest Dermatol       Date:  1978-02       Impact factor: 8.551

5.  Human skin proteases: separation and characterization of two alkaline proteases, one splitting trypsin and the other chymotrypsin substrates.

Authors:  J E Fräki; V K Hopsu-Havu
Journal:  Arch Dermatol Res       Date:  1975-10-29       Impact factor: 3.017

6.  Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors.

Authors:  J C Powers; T Tanaka; J W Harper; Y Minematsu; L Barker; D Lincoln; K V Crumley; J E Fraki; N M Schechter; G G Lazarus
Journal:  Biochemistry       Date:  1985-04-09       Impact factor: 3.162

7.  Angiotensin I conversion by human and rat chymotryptic proteinases.

Authors:  B U Wintroub; N B Schechter; G S Lazarus; C E Kaempfer; L B Schwartz
Journal:  J Invest Dermatol       Date:  1984-11       Impact factor: 8.551

8.  Mammalian tissue trypsin-like enzymes. Comparative reactivities of human skin tryptase, human lung tryptase, and bovine trypsin with peptide 4-nitroanilide and thioester substrates.

Authors:  T Tanaka; B J McRae; K Cho; R Cook; J E Fraki; D A Johnson; J C Powers
Journal:  J Biol Chem       Date:  1983-11-25       Impact factor: 5.157

9.  Tryptase from human pulmonary mast cells. Purification and characterization.

Authors:  L B Schwartz; R A Lewis; K F Austen
Journal:  J Biol Chem       Date:  1981-11-25       Impact factor: 5.157

10.  Degradation of the epidermal-dermal junction by proteolytic enzymes from human skin and human polymorphonuclear leukocytes.

Authors:  R A Briggaman; N M Schechter; J Fraki; G S Lazarus
Journal:  J Exp Med       Date:  1984-10-01       Impact factor: 14.307
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  2 in total

1.  Tryptase concentration in skin blister fluid from patients with bullous skin conditions.

Authors:  K Brockow; D Abeck; K Hermann; J Ring
Journal:  Arch Dermatol Res       Date:  1996-11       Impact factor: 3.017

2.  Immunoperoxidase and enzyme-histochemical demonstration of human skin tryptase in cutaneous mast cells in normal and mastocytoma skin.

Authors:  I T Harvima; A Naukkarinen; R J Harvima; J E Fräki
Journal:  Arch Dermatol Res       Date:  1988       Impact factor: 3.017
  2 in total

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