Literature DB >> 35300543

A rare isoflavone-quinone and a new flavanone from the roots of Dalbergia stipulacea Roxb.

Thurdpong Sribuhom1, Priyapan Posri1, Wilaiwan Khankeaw1, Chanakan Pornchoo2, Auemduan Prawan2, Sarawut Tontapha3, Vittaya Amornkitbamrung3, Chavi Yenjai1.   

Abstract

Two previously undescribed compounds, namely dalpulapans F and G (1 and 2), along with 11 known compounds were isolated from the MeOH crude extract of the roots of Dalbergia stipulacea. Dalpulapan F was found as a rare isoflavone-quinone derivative. Their structures and absolute configurations were supported by extensive spectroscopic data analysis, including 1 D and 2 D NMR, HRESIMS data, specific rotation data, and comparison of the experimental and calculated ECD data. Cytotoxicity evaluation of the isolated compounds against HepG2 and KKU-M156 cell lines revealed that isoflavonoid 9 and rotenoid 13 exhibited the most activity against the two cell lines.

Entities:  

Keywords:  Dalbergia stipulacea; HepG2; KKU-M156; isoflavone-quinone

Year:  2022        PMID: 35300543     DOI: 10.1080/14786419.2022.2053852

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  1 in total

1.  Structural modification of olibergin A, an isoflavonoid, from Dalbergia stipulacea Roxb. and its cytotoxicity.

Authors:  Supakorn Arthan; Priyapan Posri; Sookkawath Walunchapruk; Thanaset Senawong; Chavi Yenjai
Journal:  RSC Adv       Date:  2022-06-16       Impact factor: 4.036

  1 in total

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