Literature DB >> 35299995

Multi-Response Based Personalized Treatment Selection with Data from Crossover Designs for Multiple Treatments.

K B Kulasekera1, Chathura Siriwardhana2.   

Abstract

In this work we propose a novel method for treatment selection based on individual covariate information when the treatment response is multivariate and data are available from a crossover design. Our method covers any number of treatments and it can be applied for a broad set of models. The proposed method uses a rank aggregation technique to estimate an ordering of treatments based on ranked lists of treatment performance measures such as smooth conditional means and conditional probability of a response for one treatment dominating others. An empirical study demonstrates the performance of the proposed method in finite samples.

Entities:  

Keywords:  Crossover Designs; Design variables; Multiple Responses; Personalized Treatments; Single Index Models

Year:  2019        PMID: 35299995      PMCID: PMC8923529          DOI: 10.1080/03610918.2019.1656739

Source DB:  PubMed          Journal:  Commun Stat Simul Comput        ISSN: 0361-0918            Impact factor:   1.118


  16 in total

1.  Weighted rank aggregation of cluster validation measures: a Monte Carlo cross-entropy approach.

Authors:  Vasyl Pihur; Susmita Datta; Somnath Datta
Journal:  Bioinformatics       Date:  2007-05-05       Impact factor: 6.937

2.  Set-valued dynamic treatment regimes for competing outcomes.

Authors:  Eric B Laber; Daniel J Lizotte; Bradley Ferguson
Journal:  Biometrics       Date:  2014-01-08       Impact factor: 2.571

3.  ESTIMATION AND TESTING FOR PARTIALLY LINEAR SINGLE-INDEX MODELS.

Authors:  Hua Liang; Xiang Liu; Runze Li; Chih-Ling Tsai
Journal:  Ann Stat       Date:  2010-12-01       Impact factor: 4.028

4.  Linear Fitted-Q Iteration with Multiple Reward Functions.

Authors:  Daniel J Lizotte; Michael Bowling; Susan A Murphy
Journal:  J Mach Learn Res       Date:  2012-11       Impact factor: 3.654

Review 5.  Enabling personalized cancer medicine through analysis of gene-expression patterns.

Authors:  Laura J van't Veer; René Bernards
Journal:  Nature       Date:  2008-04-03       Impact factor: 49.962

6.  Estimating Individualized Treatment Rules Using Outcome Weighted Learning.

Authors:  Yingqi Zhao; Donglin Zeng; A John Rush; Michael R Kosorok
Journal:  J Am Stat Assoc       Date:  2012-09-01       Impact factor: 5.033

7.  HOX genes in ovarian cancer.

Authors:  Zoë L Kelly; Agnieszka Michael; Simon Butler-Manuel; Hardev S Pandha; Richard Gl Morgan
Journal:  J Ovarian Res       Date:  2011-09-09       Impact factor: 4.234

8.  Incorporating Patient Preferences into Estimation of Optimal Individualized Treatment Rules.

Authors:  Emily L Butler; Eric B Laber; Sonia M Davis; Michael R Kosorok
Journal:  Biometrics       Date:  2017-07-25       Impact factor: 1.701

9.  Optimization of personalized therapies for anticancer treatment.

Authors:  Alexei Vazquez
Journal:  BMC Syst Biol       Date:  2013-04-12

10.  RankAggreg, an R package for weighted rank aggregation.

Authors:  Vasyl Pihur; Susmita Datta; Somnath Datta
Journal:  BMC Bioinformatics       Date:  2009-02-19       Impact factor: 3.169

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