Literature DB >> 3529939

High-dose cytosine arabinoside in the treatment of preleukemic disorders: a leukemia intergroup study.

H D Preisler, A Raza, M Barcos, N Azarnia, R Larson, G Browman, I Walker, H Grunwald, P D'Arrigo, A Stein.   

Abstract

Fifteen patients with myelodysplastic/myeloproliferative disorders were treated with high-dose cytosine arabinoside therapy. While severe toxicity was produced in every patient, only two of the 15 patients entered complete remission and two achieved partial remission status. The therapeutic responses were confined to patients who had severe myelofibrosis of apparently recent onset.

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Year:  1986        PMID: 3529939     DOI: 10.1002/ajh.2830230207

Source DB:  PubMed          Journal:  Am J Hematol        ISSN: 0361-8609            Impact factor:   10.047


  2 in total

1.  Aggressive chemotherapy in adult primary myelodysplastic syndromes. A report on 29 cases.

Authors:  P Fenaux; J L Lai; J P Jouet; J P Pollet; F Bauters
Journal:  Blut       Date:  1988-11

2.  The evaluation of low-dose cytarabine in the treatment of myelodysplastic syndromes: a phase-III intergroup study.

Authors:  K B Miller; K Kim; F S Morrison; J N Winter; J M Bennett; R S Neiman; D R Head; P A Cassileth; M J O'Connell; K Kyungmann
Journal:  Ann Hematol       Date:  1992-10       Impact factor: 3.673

  2 in total

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