Literature DB >> 35298913

Advancing discovery of risk-altering variants for complex diseases by functionally informed fine-mapping.

You Chen1, Andrew G Clark2, Haiyuan Yu3.   

Abstract

Pinpointing causal variants at risk loci identified by genome-wide association studies (GWAS) has been a great challenge. In this issue of Neuron, Zhang et al. present a fine-mapping approach, RefMap, integrating functional genomics with GWAS summary statistics to prioritize causal variants for amyotrophic lateral sclerosis.
Copyright © 2022 Elsevier Inc. All rights reserved.

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Year:  2022        PMID: 35298913     DOI: 10.1016/j.neuron.2022.02.018

Source DB:  PubMed          Journal:  Neuron        ISSN: 0896-6273            Impact factor:   17.173


  1 in total

1.  Intervening in the spleen.

Authors:  Natasha Bray
Journal:  Nat Rev Neurosci       Date:  2022-04       Impact factor: 34.870

  1 in total

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