Literature DB >> 3529366

Characterization of a monoclonal antibody recognizing a monomorphic determinant of the alpha chain of class II DQ antigens.

J P Fermand, A Chevalier, J C Brouet.   

Abstract

We have characterized a monoclonal antibody (L2) specific for a determinant of Human DQ class II antigens. After immunoprecipitation and immunofluorescence analysis performed on a panel of DR homozygous cell lines and HLA deleted mutants, it behaves like a monomorphic anti-DQ reagent and does not react with the products of the various DR alleles. On immunoblotting, it reacts with an epitope of the DQ alpha chain.

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Year:  1986        PMID： 3529366     DOI： 10.1111/j.1365-3083.1986.tb02099.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN： 0300-9475            Impact factor:   3.487


  3 in total

1.  A new set of monoclonal antibodies to human MHC class II alpha chains demonstrates that most alpha epitopes are inaccessible on the living cell surface.

Authors:  B B Cohen; D N Crichton; C M Steel
Journal:  Immunology       Date:  1987-07       Impact factor: 7.397

2.  Major histocompatibility complex class II-expressing endothelial cells induce allospecific nonresponsiveness in naive T cells.

Authors:  F M Marelli-Berg; R E Hargreaves; P Carmichael; A Dorling; G Lombardi; R I Lechler
Journal:  J Exp Med       Date:  1996-04-01       Impact factor: 14.307

3.  Structural requirements for recognition of major histocompatibility complex class II by membrane-associated RING-CH (MARCH) protein E3 ligases.

Authors:  Martin Jahnke; John Trowsdale; Adrian P Kelly
Journal:  J Biol Chem       Date:  2012-07-03       Impact factor: 5.157
  3 in total

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