Kelly J Hunt1, Pamela L Ferguson1, Brian Neelon1, Sarah Commodore2, Michael S Bloom3, Anthony C Sciscione4, William A Grobman5, Michelle A Kominiarek5, Roger B Newman6, Alan T Tita7, Michael P Nageotte8, Kristy Palomares9, Daniel W Skupski10, Cuilin Zhang11,12, Stefanie Hinkle13, Ronald Wapner14, John E Vena1. 1. Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA. 2. Environmental and Occupational Health, Indiana University, Bloomington, Indiana, USA. 3. Global and Community Health, George Mason University, Fairfax, Virginia, USA. 4. Obstetrics and Gynecology, Christiana Care Health System, Newark, Delaware, USA. 5. Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. 6. Obstetrics and Gynecology, Medical University of South Carolina, Charleston, South Carolina, USA. 7. Obstetrics and Gynecology and Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, Alabama, USA. 8. Obstetrics and Gynecology, Miller Children's and Women's Hospital, Long Beach, California, USA. 9. Obstetrics and Gynecology, Saint Peter's University Hospital, New Brunswick, New Jersey, USA. 10. Obstetrics and Gynecology, New York Presbyterian Queens Hospital, Queens, New York, USA. 11. Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA. 12. Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. 13. Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA. 14. Obstetrics and Gynecology, Columbia University Medical Center, New York, New York, USA.
Abstract
BACKGROUND: The prevalence of obesity in US children has more than tripled in the past 40 years; hence, it is critical to identify potentially modifiable factors that may mitigate the risk. OBJECTIVES: To examine the association between maternal pre-pregnancy body mass index (BMI), gestational weight gain (GWG) and child adiposity as measured by BMI, waist circumference and percent body fat in a racial-ethnically diverse cohort. METHODS: In a prospective cohort study of healthy women without chronic disease, we examined the association between pre-pregnancy BMI, GWG and child adiposity. Children ages 4-8 years (n = 816) in the Environmental Influences on Child Health Outcomes-NICHD Fetal Growth Studies were assessed. Trained study staff ascertained maternal pre-pregnancy BMI, GWG and child adiposity. RESULTS: The odds of child obesity (≥95th BMI percentile) increased independently for each unit increase in maternal pre-pregnancy BMI [OR = 1.12 (95% CI: 1.08, 1.17)] and for each 5-kg increase in GWG [OR = 1.25 (95% CI: 1.07, 1.47)]. The odds of child waist circumference (≥85th percentile) also increased independently for pre-pregnancy BMI [OR = 1.09 (95% CI: 1.05, 1.12)] and GWG [OR = 1.18 (95% CI: 1.04, 1.34)]. CONCLUSIONS: Maternal pre-pregnancy BMI and GWG were each independently and positively associated with child obesity and high child waist circumference.
BACKGROUND: The prevalence of obesity in US children has more than tripled in the past 40 years; hence, it is critical to identify potentially modifiable factors that may mitigate the risk. OBJECTIVES: To examine the association between maternal pre-pregnancy body mass index (BMI), gestational weight gain (GWG) and child adiposity as measured by BMI, waist circumference and percent body fat in a racial-ethnically diverse cohort. METHODS: In a prospective cohort study of healthy women without chronic disease, we examined the association between pre-pregnancy BMI, GWG and child adiposity. Children ages 4-8 years (n = 816) in the Environmental Influences on Child Health Outcomes-NICHD Fetal Growth Studies were assessed. Trained study staff ascertained maternal pre-pregnancy BMI, GWG and child adiposity. RESULTS: The odds of child obesity (≥95th BMI percentile) increased independently for each unit increase in maternal pre-pregnancy BMI [OR = 1.12 (95% CI: 1.08, 1.17)] and for each 5-kg increase in GWG [OR = 1.25 (95% CI: 1.07, 1.47)]. The odds of child waist circumference (≥85th percentile) also increased independently for pre-pregnancy BMI [OR = 1.09 (95% CI: 1.05, 1.12)] and GWG [OR = 1.18 (95% CI: 1.04, 1.34)]. CONCLUSIONS: Maternal pre-pregnancy BMI and GWG were each independently and positively associated with child obesity and high child waist circumference.
Authors: Jennifer A Woo Baidal; Lindsey M Locks; Erika R Cheng; Tiffany L Blake-Lamb; Meghan E Perkins; Elsie M Taveras Journal: Am J Prev Med Date: 2016-02-22 Impact factor: 5.043
Authors: Yeyi Zhu; Ladia M Hernandez; Yongquan Dong; John H Himes; Steven Hirschfeld; Michele R Forman Journal: J Epidemiol Community Health Date: 2015-02-13 Impact factor: 3.710
Authors: Germaine M Buck Louis; Jagteshwar Grewal; Paul S Albert; Anthony Sciscione; Deborah A Wing; William A Grobman; Roger B Newman; Ronald Wapner; Mary E D'Alton; Daniel Skupski; Michael P Nageotte; Angela C Ranzini; John Owen; Edward K Chien; Sabrina Craigo; Mary L Hediger; Sungduk Kim; Cuilin Zhang; Katherine L Grantz Journal: Am J Obstet Gynecol Date: 2015-10 Impact factor: 8.661