Literature DB >> 35288683

Promising reversible protein inhibitors kept on target.

Stephan M Hacker.   

Abstract

Entities:  

Keywords:  Chemical biology; Drug discovery

Mesh：

Year:  2022        PMID： 35288683     DOI： 10.1038/d41586-022-00692-5

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


× No keyword cloud information.
  10 in total

1.  Iminoboronates: a new strategy for reversible protein modification.

Authors:  Pedro M S D Cal; João B Vicente; Elisabete Pires; Ana V Coelho; Luís F Veiros; Carlos Cordeiro; Pedro M P Gois
Journal:  J Am Chem Soc       Date:  2012-06-11       Impact factor: 15.419

Review 2.  The resurgence of covalent drugs.

Authors:  Juswinder Singh; Russell C Petter; Thomas A Baillie; Adrian Whitty
Journal:  Nat Rev Drug Discov       Date:  2011-04       Impact factor: 84.694

3.  10 years into the resurgence of covalent drugs.

Authors:  Elena De Vita
Journal:  Future Med Chem       Date:  2020-12-04       Impact factor: 3.808

4.  Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain.

Authors:  Gizem Akçay; Matthew A Belmonte; Brian Aquila; Claudio Chuaqui; Alexander W Hird; Michelle L Lamb; Philip B Rawlins; Nancy Su; Sharon Tentarelli; Neil P Grimster; Qibin Su
Journal:  Nat Chem Biol       Date:  2016-09-05       Impact factor: 15.040

5.  Global profiling of lysine reactivity and ligandability in the human proteome.

Authors:  Stephan M Hacker; Keriann M Backus; Michael R Lazear; Stefano Forli; Bruno E Correia; Benjamin F Cravatt
Journal:  Nat Chem       Date:  2017-07-31       Impact factor: 24.427

6.  A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease.

Authors:  Elliott Vichinsky; Carolyn C Hoppe; Kenneth I Ataga; Russell E Ware; Videlis Nduba; Amal El-Beshlawy; Hoda Hassab; Maureen M Achebe; Salam Alkindi; R Clark Brown; David L Diuguid; Paul Telfer; Dimitris A Tsitsikas; Ashraf Elghandour; Victor R Gordeuk; Julie Kanter; Miguel R Abboud; Joshua Lehrer-Graiwer; Margaret Tonda; Allison Intondi; Barbara Tong; Jo Howard
Journal:  N Engl J Med       Date:  2019-06-14       Impact factor: 91.245

7.  SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*.

Authors:  Tianyang Yan; Heta S Desai; Lisa M Boatner; Stephanie L Yen; Jian Cao; Maria F Palafox; Yasaman Jami-Alahmadi; Keriann M Backus
Journal:  Chembiochem       Date:  2021-02-18       Impact factor: 3.164

8.  Lysine-Targeting Reversible Covalent Inhibitors with Long Residence Time.

Authors:  Rahi M Reja; Wenjian Wang; Yuhan Lyu; Fredrik Haeffner; Jianmin Gao
Journal:  J Am Chem Soc       Date:  2022-01-18       Impact factor: 15.419

9.  Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles.

Authors:  Iana M Serafimova; Miles A Pufall; Shyam Krishnan; Katarzyna Duda; Michael S Cohen; Rebecca L Maglathlin; Jesse M McFarland; Rand M Miller; Morten Frödin; Jack Taunton
Journal:  Nat Chem Biol       Date:  2012-04-01       Impact factor: 15.040

10.  A proteome-wide atlas of lysine-reactive chemistry.

Authors:  Mikail E Abbasov; Madeline E Kavanagh; Taka-Aki Ichu; Michael R Lazear; Yongfeng Tao; Vincent M Crowley; Christopher W Am Ende; Stephan M Hacker; Jordan Ho; Melissa M Dix; Radu Suciu; Matthew M Hayward; Laura L Kiessling; Benjamin F Cravatt
Journal:  Nat Chem       Date:  2021-09-09       Impact factor: 24.274
  10 in total
  1 in total

Review 1.  Pathobiology and Therapeutic Relevance of GSK-3 in Chronic Hematological Malignancies.

Authors:  Alberto M Martelli; Francesca Paganelli; Camilla Evangelisti; Francesca Chiarini; James A McCubrey
Journal:  Cells       Date:  2022-05-31       Impact factor: 7.666
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.