Soyoung Lee1, Yichen Jia2, Beth E Snitz3, Chung-Chou H Chang2,4, Mary Ganguli5,3,6. 1. Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, MD. 2. Departments of Biostatistics. 3. Departments of Neurology. 4. Medicine. 5. Epidemiology, Graduate School of Public Health. 6. Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA.
Abstract
OBJECTIVES: In a population-based study of mild cognitive impairment (MCI), to validate the assessment of social cognition in older adults. METHODS: Cross-sectional study of 902 adults aged 65+ with mean age 76.6 years (SD 8.06). We created a social cognition composite comprising standardized z scores on the Social Norms Questionnaire and the 10-item Reading the Mind in the Eyes Test. We identified associated factors and compared sensitivity, specificity, and the area under the curve of social cognition, for MCI defined as Clinical Dementia Rating (CDR)=0.5, to those of other cognitive domains. We calculated the impact of including social cognition on the proportion neuropsychologically classified as MCI. RESULTS: Better social cognition was associated with younger age, female sex, higher education, better general cognition (mini-mental state examination), fewer depressive symptoms, and lower CDR. Adjusting for demographics, associations with mini-mental state examination, depressive symptoms, anxiety symptoms, and subjective cognitive complaints remained significant. The sensitivity and specificity of social cognition for CDR=0.5 were comparable to those of the traditional 5 cognitive domains. Including social cognition as a sixth domain of cognition resulted in a 5% increase in the proportion classified as MCI. CONCLUSIONS: Brief objective assessment of social cognition may enhance cognitive assessment of older adults.
OBJECTIVES: In a population-based study of mild cognitive impairment (MCI), to validate the assessment of social cognition in older adults. METHODS: Cross-sectional study of 902 adults aged 65+ with mean age 76.6 years (SD 8.06). We created a social cognition composite comprising standardized z scores on the Social Norms Questionnaire and the 10-item Reading the Mind in the Eyes Test. We identified associated factors and compared sensitivity, specificity, and the area under the curve of social cognition, for MCI defined as Clinical Dementia Rating (CDR)=0.5, to those of other cognitive domains. We calculated the impact of including social cognition on the proportion neuropsychologically classified as MCI. RESULTS: Better social cognition was associated with younger age, female sex, higher education, better general cognition (mini-mental state examination), fewer depressive symptoms, and lower CDR. Adjusting for demographics, associations with mini-mental state examination, depressive symptoms, anxiety symptoms, and subjective cognitive complaints remained significant. The sensitivity and specificity of social cognition for CDR=0.5 were comparable to those of the traditional 5 cognitive domains. Including social cognition as a sixth domain of cognition resulted in a 5% increase in the proportion classified as MCI. CONCLUSIONS: Brief objective assessment of social cognition may enhance cognitive assessment of older adults.
Authors: Tal Shany-Ur; Nancy Lin; Howard J Rosen; Marc Sollberger; Bruce L Miller; Katherine P Rankin Journal: Brain Date: 2014-06-20 Impact factor: 13.501
Authors: Mary Ganguli; Joni Vander Bilt; Ching-Wen Lee; Beth E Snitz; Chung-Chou H Chang; David A Loewenstein; Judith A Saxton Journal: J Int Neuropsychol Soc Date: 2010-07-08 Impact factor: 2.892
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