Peter Y M Woo1, Oliver K S Ng2, Ronald P T Li3, Kwong-Yau Chan3. 1. Department of Neurosurgery, Kwong Wah Hospital, Hong Kong, Hong Kong. wym307@ha.org.hk. 2. Department of Anatomical Pathology, Kwong Wah Hospital, Hong Kong, Hong Kong. 3. Department of Neurosurgery, Kwong Wah Hospital, Hong Kong, Hong Kong.
Abstract
BACKGROUND: Meningo-cerebral adhesions are frequently encountered during recurrent high-grade glioma resections. Adhesiolysis not only lengthens operation times, but can also induce focal cortical tissue injury that could affect overall survival. METHODS: Immediately after the primary resection of a high-grade glioma, a polyesterurethane interpositional graft was implanted in the subdural space covering the entire exposed cortex as well as beneath the dural suture line. No postoperative complications were documented. All patients received adjuvant radiotherapy. Upon repeat resection for focal tumor recurrence, the graft was shown to effectively reduce meningo-cerebral adhesion development. CONCLUSION: The implantation of a synthetic subdural graft is a safe and effective method for preventing meningo-cerebral adhesions.
BACKGROUND: Meningo-cerebral adhesions are frequently encountered during recurrent high-grade glioma resections. Adhesiolysis not only lengthens operation times, but can also induce focal cortical tissue injury that could affect overall survival. METHODS: Immediately after the primary resection of a high-grade glioma, a polyesterurethane interpositional graft was implanted in the subdural space covering the entire exposed cortex as well as beneath the dural suture line. No postoperative complications were documented. All patients received adjuvant radiotherapy. Upon repeat resection for focal tumor recurrence, the graft was shown to effectively reduce meningo-cerebral adhesion development. CONCLUSION: The implantation of a synthetic subdural graft is a safe and effective method for preventing meningo-cerebral adhesions.
Authors: Hardean E Achneck; Bantayehu Sileshi; Ryan M Jamiolkowski; David M Albala; Mark L Shapiro; Jeffrey H Lawson Journal: Ann Surg Date: 2010-02 Impact factor: 12.969