| Literature DB >> 35276072 |
Alexis Aiman1, Santu Saha2, Woon H Chong3, Biplab K Saha4.
Abstract
Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of recurrent episodes of diffuse alveolar hemorrhage (DAH). IPH commonly manifests with hemoptysis, radiologic chest infiltrates and anemia. The etiology of IPH is unknown, but an immunologic mechanism is widely speculated. The definitive diagnosis of IPH requires a thorough exclusion of other causes of DAH, such as infections, inflammation, malignancy, cardiac diseases, drug and toxin exposure, and medications. Due to the rarity of the disease, a diagnosis is often delayed by years. We present the case of a 49-year-old man with ischemic cardiomyopathy who presented with hemoptysis for eighteen months. Serologic workup was negative for vasculitides and autoimmune diseases. Bronchoscopy revealed DAH. A surgical lung biopsy showed 'bland pulmonary hemorrhage.' A right heart catheterization ruled out cardiac causes of DAH. The patient was diagnosed with IPH and started on systemic corticosteroids with rapid improvement of hemoptysis.Entities:
Keywords: Corticosteroid; Hemoptysis; Idiopathic pulmonary hemosiderosis; Pulmonary hemorrhage
Mesh:
Year: 2022 PMID: 35276072 DOI: 10.1016/j.amjms.2021.10.030
Source DB: PubMed Journal: Am J Med Sci ISSN: 0002-9629 Impact factor: 3.462