Literature DB >> 35276072

A 49-year-old man with ischemic cardiomyopathy and persistent hemoptysis for eighteen months.

Alexis Aiman1, Santu Saha2, Woon H Chong3, Biplab K Saha4.   

Abstract

Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of recurrent episodes of diffuse alveolar hemorrhage (DAH). IPH commonly manifests with hemoptysis, radiologic chest infiltrates and anemia. The etiology of IPH is unknown, but an immunologic mechanism is widely speculated. The definitive diagnosis of IPH requires a thorough exclusion of other causes of DAH, such as infections, inflammation, malignancy, cardiac diseases, drug and toxin exposure, and medications. Due to the rarity of the disease, a diagnosis is often delayed by years. We present the case of a 49-year-old man with ischemic cardiomyopathy who presented with hemoptysis for eighteen months. Serologic workup was negative for vasculitides and autoimmune diseases. Bronchoscopy revealed DAH. A surgical lung biopsy showed 'bland pulmonary hemorrhage.' A right heart catheterization ruled out cardiac causes of DAH. The patient was diagnosed with IPH and started on systemic corticosteroids with rapid improvement of hemoptysis.
Copyright © 2022 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Corticosteroid; Hemoptysis; Idiopathic pulmonary hemosiderosis; Pulmonary hemorrhage

Mesh:

Year:  2022        PMID: 35276072     DOI: 10.1016/j.amjms.2021.10.030

Source DB:  PubMed          Journal:  Am J Med Sci        ISSN: 0002-9629            Impact factor:   3.462


  2 in total

Review 1.  The Spectrum of Autoantibodies in Adult Patients With Idiopathic Pulmonary Hemosiderosis: A Brief Review of the Literature.

Authors:  Biplab K Saha; Alyssa Bonnier; Santu Saha; Baidya N Saha; Nils T Milman
Journal:  Cureus       Date:  2022-04-15

Review 2.  Comparative Analysis of Adult Patients With Idiopathic Pulmonary Hemosiderosis and Lane-Hamilton Syndrome: A Systematic Review of the Literature in the Period 1971-2022.

Authors:  Biplab K Saha; Praveen Datar; Alexis Aiman; Alyssa Bonnier; Santu Saha; Nils T Milman
Journal:  Cureus       Date:  2022-03-25
  2 in total

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