Ihn Sook Jeong1, Eun Joo Lee2, Myo Sung Kim3, Jung Ok Yu4, Hae Sun Yun5, Jeong Hee Jeong6, Youn Sun Hwang7. 1. College of Nursing, Pusan National University, Yangsan, Korea. 2. Department of Nursing, Dong-Eui University, Busan, Korea. ej.lee@deu.ac.kr. 3. Department of Nursing, Dong-Eui University, Busan, Korea. 4. College of Nursing, Dong-A University, Busan, Korea. 5. Department of Nursing Science, Kyungsung University, Busan, Korea. 6. Department of Nursing, Daedong College, Busan, Korea. 7. Department of Nursing, Dongseo University, Busan, Korea.
Abstract
PURPOSE: This study investigated the incidence and risk factors of cataract in people with diabetes mellitus (DM) using data from Ansan cohort of the Korean Genome and Epidemiology Study (KoGES). METHODS: Data from a total of 329 patients with type 2 DM without cataract who participated in Ansan cohort of the KoGES from baseline survey (2001-2002) to fifth follow-up visit (2011-2012) were examined. The characteristics of the subjects were analyzed with frequency and percentage, and mean and standard deviation. Cataract incidence was measured as incidence proportion (%). For risk factors of cataract, hazard ratio (HR) and 95% confidence interval (CI) were obtained using the Cox proportional hazard model. RESULTS: The cataract incidence over a 10-year follow-up period was 19.1% (15.1 in males and 25.8 in females), and mean age at the incidence of cataract was 63.48 years (61.58 years in males and 65.31 years in females). Age (HR=1.09, 95% CI=1.05-1.13) and HbA1c (HR=1.21, 95% CI=1.07-1.37) or the duration of DM (HR=1.05, 95% CI=1.00-1.09) were found to be independently associated with cataract development. CONCLUSION: Cataract development in people with DM is common, and its likelihood increases with age, HbA1c, and the duration of DM. Considering negative effect of cataract on their quality of life and economic burden, nurses should identify people with DM at a higher risk of cataract development, and plan individual eye examination programs to detect cataract development as early as possible.
PURPOSE: This study investigated the incidence and risk factors of cataract in people with diabetes mellitus (DM) using data from Ansan cohort of the Korean Genome and Epidemiology Study (KoGES). METHODS: Data from a total of 329 patients with type 2 DM without cataract who participated in Ansan cohort of the KoGES from baseline survey (2001-2002) to fifth follow-up visit (2011-2012) were examined. The characteristics of the subjects were analyzed with frequency and percentage, and mean and standard deviation. Cataract incidence was measured as incidence proportion (%). For risk factors of cataract, hazard ratio (HR) and 95% confidence interval (CI) were obtained using the Cox proportional hazard model. RESULTS: The cataract incidence over a 10-year follow-up period was 19.1% (15.1 in males and 25.8 in females), and mean age at the incidence of cataract was 63.48 years (61.58 years in males and 65.31 years in females). Age (HR=1.09, 95% CI=1.05-1.13) and HbA1c (HR=1.21, 95% CI=1.07-1.37) or the duration of DM (HR=1.05, 95% CI=1.00-1.09) were found to be independently associated with cataract development. CONCLUSION: Cataract development in people with DM is common, and its likelihood increases with age, HbA1c, and the duration of DM. Considering negative effect of cataract on their quality of life and economic burden, nurses should identify people with DM at a higher risk of cataract development, and plan individual eye examination programs to detect cataract development as early as possible.
Authors: Jacqueline Chua; Blanche Lim; Eva K Fenwick; Alfred Tau Liang Gan; Ava Grace Tan; Ecosse Lamoureux; Paul Mitchell; Jie Jin Wang; Tien Yin Wong; Ching-Yu Cheng Journal: PLoS One Date: 2017-01-27 Impact factor: 3.240