Literature DB >> 3527167

The complete amino acid sequence of human brain-derived acidic fibroblast growth factor.

G Gimenez-Gallego, G Conn, V B Hatcher, K A Thomas.   

Abstract

Acidic fibroblast growth factor is a potent mitogen for a variety of cells in culture, including vascular endothelial cells, and is angiogenic in vivo. The complete amino acid sequence of human brain-derived acidic fibroblast growth factor has been determined from amino terminal sequence analysis and carboxypeptidase A digestion of the whole protein and sequence analyses of peptides generated by tryptic, Staphylococcus aureus V8 protease and cyanogen bromide cleavages. A potential Asn-Gly-Ser glycosylation sequence is present in the human protein. The complete amino acid sequence is compared to that of the equivalent protein purified from bovine brain.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3527167     DOI： 10.1016/s0006-291x(86)80540-x

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  24 in total

1.  Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.

Authors:  S R Brych; S I Blaber; T M Logan; M Blaber
Journal:  Protein Sci       Date:  2001-12       Impact factor: 6.725

2.  Accommodation of a highly symmetric core within a symmetric protein superfold.

Authors:  Stephen R Brych; Jaewon Kim; Timothy M Logan; Michael Blaber
Journal:  Protein Sci       Date:  2003-12       Impact factor: 6.725

3.  An empirical phase diagram approach to investigate conformational stability of "second-generation" functional mutants of acidic fibroblast growth factor-1.

Authors:  Mohammad A Alsenaidy; Tingting Wang; Jae Hyun Kim; Sangeeta B Joshi; Jihun Lee; Michael Blaber; David B Volkin; C Russell Middaugh
Journal:  Protein Sci       Date:  2012-02-06       Impact factor: 6.725

4.  Redesigning symmetry-related "mini-core" regions of FGF-1 to increase primary structure symmetry: thermodynamic and functional consequences of structural symmetry.

Authors:  Vikash Kumar Dubey; Jihun Lee; Michael Blaber
Journal:  Protein Sci       Date:  2005-08-04       Impact factor: 6.725

5.  Purification of a glycoprotein vascular endothelial cell mitogen from a rat glioma-derived cell line.

Authors:  G Conn; D D Soderman; M T Schaeffer; M Wile; V B Hatcher; K A Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

6.  An S116R Phosphorylation Site Mutation in Human Fibroblast Growth Factor-1 Differentially Affects Mitogenic and Glucose-Lowering Activities.

Authors:  Xue Xia; Ozan S Kumru; Sachiko I Blaber; C Russell Middaugh; Ling Li; David M Ornitz; Jae Myoung Suh; Annette R Atkins; Michael Downes; Ronald M Evans; Connie A Tenorio; Ewa Bienkiewicz; Michael Blaber
Journal:  J Pharm Sci       Date:  2016-10-20       Impact factor: 3.534

7.  Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor.

Authors:  Jaewon Kim; Sachiko I Blaber; Michael Blaber
Journal:  Protein Sci       Date:  2002-03       Impact factor: 6.725

8.  Cloning of the gene coding for human class 1 heparin-binding growth factor and its expression in fetal tissues.

Authors:  W P Wang; K Lehtoma; M L Varban; I Krishnan; I M Chiu
Journal:  Mol Cell Biol       Date:  1989-06       Impact factor: 4.272

9.  Mitogenic activity of acidic fibroblast growth factor is enhanced by highly sulfated oligosaccharides derived from heparin and heparan sulfate.

Authors:  A G Gambarini; C A Miyamoto; G A Lima; H B Nader; C P Dietrich
Journal:  Mol Cell Biochem       Date:  1993-07-21       Impact factor: 3.396

10.  Increased protein stability of FGF1 can compensate for its reduced affinity for heparin.

Authors:  Malgorzata Zakrzewska; Antoni Wiedlocha; Anna Szlachcic; Daniel Krowarsch; Jacek Otlewski; Sjur Olsnes
Journal:  J Biol Chem       Date:  2009-07-02       Impact factor: 5.157
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.