Literature DB >> 3526910

Distinct histologic patterns of acute, prolonged, and chronic rejection in vascularized rat pancreas allografts.

B Steiniger, J Klempnauer.   

Abstract

In a model of pancreas whole organ transplantation in streptozotocin diabetic rats distinct histologic patterns of acute, prolonged and chronic rejection were defined by light microscopy. Allotransplantation between major histocompatibility complex (MHC) congenic and recombinant rat strains allowed an immunogenetic analysis of the effect of defined histocompatibility antigens on graft morphology. The impact of surgical techniques with preserved and suppressed exocrine secretion on graft histology was sequentially assessed in pancreas isograft recipients. MHC incompatibility was associated with acute rejection, non-MHC disparity with prolonged rejection and RT1.C mismatch with chronic rejection.

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Year:  1986        PMID: 3526910      PMCID: PMC1888289     

Source DB:  PubMed          Journal:  Am J Pathol        ISSN: 0002-9440            Impact factor:   4.307


  12 in total

1.  Chronic kidney allograft reactions in rats.

Authors:  E White; W H Hildemann; Y Mullen
Journal:  Transplantation       Date:  1969-11       Impact factor: 4.939

2.  Influence of pancreatic duct anastomosis on function of autotransplanted canine pancreatic segments.

Authors:  C Rausis; A Choudhury; Y Ogata
Journal:  J Surg Res       Date:  1970-11       Impact factor: 2.192

3.  Pancreatic morphology and blood glucose level in rats at various intervals after duct ligation.

Authors:  C Edström; S Falkmer
Journal:  Virchows Arch A Pathol Pathol Anat       Date:  1968

4.  Altered distribution of class I and class II MHC antigens during acute pancreas allograft rejection in the rat.

Authors:  B Steiniger; J Klempnauer; K Wonigeit
Journal:  Transplantation       Date:  1985-09       Impact factor: 4.939

5.  Long term studies of pancreas transplantation in experimental diabetes mellitus.

Authors:  M J Orloff; S Lee; A C Charters; D E Grambort; L G Storck; D Knox
Journal:  Ann Surg       Date:  1975-09       Impact factor: 12.969

6.  An autoradiographic study of the cell proliferation during involution of the rat pancreas.

Authors:  N I Walker; A W Pound
Journal:  J Pathol       Date:  1983-04       Impact factor: 7.996

7.  Relative contributions of insulin deficiency and insulin resistance in maturity-onset diabetes.

Authors:  R C Turner; D R Mathews; R R Holman; J Peto
Journal:  Lancet       Date:  1982-03-13       Impact factor: 79.321

8.  The effect of duct obliteration on the histology and endocrine function of the canine pancreas.

Authors:  H G Gooszen; F T Bosman; R van Schilfgaarde
Journal:  Transplantation       Date:  1984-07       Impact factor: 4.939

9.  Rat pancreas allotransplantation: a short term comparison of rejection patterns with different methods of exocrine drainage.

Authors:  N J Lindsey; M S Nolan; D N Slater; C P Savas; P F Boyle; A Herold; S Beck; M Fox
Journal:  J Pathol       Date:  1983-03       Impact factor: 7.996

10.  Morphological findings in duct-ligated pancreas grafts in the rat. An analysis of isografts, allografts, and long-standing allografts in hosts conditioned by previous spleen allograft.

Authors:  K H Shah; H Bitter-Suermann; J Save-Soderbergh
Journal:  Transplantation       Date:  1980-08       Impact factor: 4.939

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  5 in total

1.  Identical pattern of acute rejection after isolated islet and vascularized whole-pancreas transplantation in the rat.

Authors:  B Steiniger; W F Hiller; J Klempnauer
Journal:  Am J Pathol       Date:  1990-07       Impact factor: 4.307

2.  Genetic control of rat heart allograft rejection: effect of different MHC and non-MHC incompatibilities.

Authors:  J Klempnauer; B Steiniger; R Lück; E Günther
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

3.  [Suppression of exocrine secretion does not lead to disruption of endocrine function of pancreas transplants].

Authors:  J Klempnauer; R Lück; U Brüsch; B Steiniger
Journal:  Langenbecks Arch Chir       Date:  1990

4.  Endothelial-cell injury in cutaneous acute graft-versus-host disease.

Authors:  J S Dumler; W E Beschorner; E R Farmer; K A Di Gennaro; R Saral; G W Santos
Journal:  Am J Pathol       Date:  1989-12       Impact factor: 4.307

5.  Longitudinal histopathologic assessment of rejection after bladder-drained canine pancreas allograft transplantation.

Authors:  R D Allen; J M Grierson; H Ekberg; W J Hawthorne; P Williamson; S A Deane; J R Chapman; G J Stewart; J M Little
Journal:  Am J Pathol       Date:  1991-02       Impact factor: 4.307

  5 in total

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