Literature DB >> 35262676

Standing Watch: Immune Activation and Failure in Melanoma Sentinel Lymph Nodes.

Amanda W Lund1.   

Abstract

An unbiased approach to map the sentinel lymph node landscape reveals progressive immune dysfunction associated with micrometastasis in patients with stage I-III cutaneous melanoma. Evidence of tumor-induced lymph node dysfunction may motivate new hypotheses for neoadjuvant therapy with potential to reinvigorate endogenous antitumor immunity. See related article by Yaddanapudi et al., p. 2069. ©2022 American Association for Cancer Research.

Entities:  

Mesh：

Year:  2022        PMID： 35262676      PMCID： PMC9106852          DOI： 10.1158/1078-0432.CCR-22-0214

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   13.801


  6 in total

1.  Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma.

Authors:  E P Hoefsmit; I L M Reijers; E A Rozeman; R P M Saw; J M Versluis; O Krijgsman; P Dimitriadis; K Sikorska; B A van de Wiel; H Eriksson; M Gonzalez; A Torres Acosta; L G Grijpink-Ongering; K Shannon; J B A G Haanen; J Stretch; S Ch'ng; O E Nieweg; H A Mallo; S Adriaansz; R M Kerkhoven; S Cornelissen; A Broeks; W M C Klop; C L Zuur; W J van Houdt; D S Peeper; A J Spillane; A C J van Akkooi; R A Scolyer; T N M Schumacher; A M Menzies; G V Long; C U Blank
Journal:  Nat Med       Date:  2021-02-08       Impact factor: 53.440

Review 2.  Tumor-draining lymph nodes: At the crossroads of metastasis and immunity.

Authors:  Haley du Bois; Taylor A Heim; Amanda W Lund
Journal:  Sci Immunol       Date:  2021-09-03

3.  Melanoma Prognosis: Accuracy of the American Joint Committee on Cancer Staging Manual Eighth Edition.

Authors:  Shirin Bajaj; Douglas Donnelly; Melissa Call; Paul Johannet; Una Moran; David Polsky; Richard Shapiro; Russell Berman; Anna Pavlick; Jeffrey Weber; Judy Zhong; Iman Osman
Journal:  J Natl Cancer Inst       Date:  2020-09-01       Impact factor: 13.506

4.  Single-Cell Immune Mapping of Melanoma Sentinel Lymph Nodes Reveals an Actionable Immunotolerant Microenvironment.

Authors:  Kavitha Yaddanapudi; Bryce F Stamp; Priyanka B Subrahmanyam; Andrei Smolenkov; Sabine J Waigel; Rahul Gosain; Michael E Egger; Robert C G Martin; Robert Buscaglia; Holden T Maecker; Kelly M McMasters; Jason A Chesney
Journal:  Clin Cancer Res       Date:  2022-05-13       Impact factor: 12.531

5.  Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma.

Authors:  Aleksey K Molodtsov; Nikhil Khatwani; Jennifer L Vella; Kathryn A Lewis; Yanding Zhao; Jichang Han; Delaney E Sullivan; Tyler G Searles; Nicholas K Preiss; Tamer B Shabaneh; Peisheng Zhang; Aaron R Hawkes; Brian T Malik; Fred W Kolling; Edward J Usherwood; Sandra L Wong; Joseph D Phillips; Keisuke Shirai; Christina V Angeles; Shaofeng Yan; Tyler J Curiel; Yina H Huang; Chao Cheng; Mary Jo Turk
Journal:  Immunity       Date:  2021-09-14       Impact factor: 43.474

6.  Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy.

Authors:  David M Francis; Margaret P Manspeaker; Alex Schudel; Lauren F Sestito; Meghan J O'Melia; Haydn T Kissick; Brian P Pollack; Edmund K Waller; Susan N Thomas
Journal:  Sci Transl Med       Date:  2020-09-30       Impact factor: 17.956
  6 in total

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