Ioanina Parlatescu1, Carmen Nicolae1, Serban Tovaru1, Lavinia Radu2, Ovidiu Penes3, Valentin Varlas4. 1. Oral Medicine Department, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania. 2. "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania. 3. Department of Anesthesiology and Intensive Care, University Clinical Hospital, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania. 4. Department of Obstetrics and Gynecology, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Abstract
Objectives: The purpose of this study is to determine if superimposed infection with Candida species in oral lichen planus exacerbates the clinical symptoms and lesions. Methodology:We conducted a retrospective study on the medical charts of oral lichen planus (OLP) patients diagnosed by clinical and histopathological criteria. A baseline demographic, anamnestic, clinical data, results of the oral candida investigations were analyzed and recorded for all patients. Results: From a total number of 203 OLP patients, oral candidiasis was diagnosed in 75 (36.94%) cases. There was no statistical significance between the clinical forms of lichen planus and the presence of Candida infection. Of all encountered Candida species, Candida albicans was most commonly detected, followed by Candida krusei, Candida lusitaniae, and Candida tropicalis. Conclusion: Although our study is limited regarding the sample size and no statistically significant difference has been found between clinical features of OLP and oral candidiasis, a routine screening of OLP patients for oral candidiasis and a preventive antifungal strategy in the OLP treatment schedule is needed.
Objectives: The purpose of this study is to determine if superimposed infection with Candida species in oral lichen planus exacerbates the clinical symptoms and lesions. Methodology:We conducted a retrospective study on the medical charts of oral lichen planus (OLP) patients diagnosed by clinical and histopathological criteria. A baseline demographic, anamnestic, clinical data, results of the oral candida investigations were analyzed and recorded for all patients. Results: From a total number of 203 OLP patients, oral candidiasis was diagnosed in 75 (36.94%) cases. There was no statistical significance between the clinical forms of lichen planus and the presence of Candida infection. Of all encountered Candida species, Candida albicans was most commonly detected, followed by Candida krusei, Candida lusitaniae, and Candida tropicalis. Conclusion: Although our study is limited regarding the sample size and no statistically significant difference has been found between clinical features of OLP and oral candidiasis, a routine screening of OLP patients for oral candidiasis and a preventive antifungal strategy in the OLP treatment schedule is needed.
Authors: D R Marable; L M Bowers; T L Stout; C M Stewart; K M Berg; V Sankar; S S DeRossi; J R Thoppay; M T Brennan Journal: Oral Dis Date: 2016-01-13 Impact factor: 3.511
Authors: Paula Boñar-Alvarez; Mario Pérez Sayáns; Abel Garcia-Garcia; Cintia Chamorro-Petronacci; Pilar Gándara-Vila; Romina Luces-González; Eva Otero Rey; Andres Blanco-Carrión; J M Suárez-Peñaranda Journal: Medicine (Baltimore) Date: 2019-02 Impact factor: 1.889