| Literature DB >> 35260092 |
Yiqi Zhang1, Xi Lan1, Fei Li1, Hong Sun1, Ju Zhang2, Run Li2, Yan Gao3, Hongli Dong1, Congjie Cai1, Guo Zeng4.
Abstract
Entities:
Year: 2022 PMID: 35260092 PMCID: PMC8903159 DOI: 10.1186/s12884-022-04489-2
Source DB: PubMed Journal: BMC Pregnancy Childbirth ISSN: 1471-2393 Impact factor: 3.007
Characteristics and dietary intake of participants according to quartile of total cholesterol intake
| Characteristic | Overall | Quartile of total cholesterol intake(mg/d) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Q1(≤186.0) | Q2(186.1-332.0) | Q3(332.1-464.0) | Q4(>464.0) | ||||||||
| 1617 | 408 | 404 | 401 | 404 | |||||||
| Age, years (mean, SD) | 28.6 | 4.1 | 28.0 | 3.8 | 28.5 | 3.9 | 29.0 | 4.4 | 28.9 | 4.1 | 0.001 |
| Prepregnancy BMI, kg/m2 (mean, SD) | 21.1 | 3.1 | 21.2 | 3.2 | 21.1 | 3.1 | 21.3 | 3.0 | 20.9 | 3.0 | 0.249 |
| Parity (N, %) | |||||||||||
| Primiparous | 1157 | 71.6 | 290 | 71.1 | 286 | 70.8 | 293 | 73.1 | 288 | 71.3 | 0.890 |
| Multiparous | 460 | 28.4 | 118 | 28.9 | 118 | 29.2 | 108 | 26.9 | 116 | 28.7 | |
| Family history of diabetes (N, %) | 162 | 10.0 | 40 | 9.8 | 40 | 9.9 | 41 | 10.2 | 41 | 10.1 | 0.997 |
| Education (N, %) | |||||||||||
| High school or lower | 387 | 23.9 | 103 | 25.2 | 109 | 27.0 | 96 | 23.9 | 79 | 19.6 | <0.001 |
| Junior college | 590 | 36.5 | 175 | 42.9 | 135 | 33.4 | 146 | 36.4 | 134 | 33.2 | |
| University or higher | 640 | 39.6 | 130 | 31.9 | 160 | 39.6 | 159 | 39.7 | 191 | 47.3 | |
| Monthly income of the family per capita, yuan (N, %) | |||||||||||
| ≤5000 | 535 | 33.1 | 147 | 36.0 | 125 | 30.9 | 134 | 33.4 | 129 | 31.9 | 0.215 |
| 5000~9999 | 743 | 45.9 | 192 | 47.1 | 191 | 47.3 | 184 | 45.9 | 176 | 43.6 | |
| ≥10000 | 339 | 21.0 | 69 | 16.9 | 88 | 21.8 | 83 | 20.7 | 99 | 24.5 | |
| Smoking before pregnancy (N, %) | 61 | 3.8 | 17 | 4.2 | 10 | 2.5 | 12 | 3.0 | 22 | 5.5 | 0.119 |
| Alcohol consumption before pregnancy (N, %) | 131 | 8.1 | 34 | 8.3 | 23 | 5.7 | 28 | 7.0 | 46 | 11.4 | 0.021 |
| WGPO, kg (mean, SD) | 6.20 | 3.31 | 5.64 | 3.26 | 6.43 | 3.25 | 6.27 | 3.26 | 6.44 | 3.40 | 0.001 |
| Physical activity, MET-h wk-1 (mean, SD) | 106.8 | 46.4 | 105.3 | 48.8 | 108.7 | 49.0 | 105.8 | 41.9 | 107.4 | 45.5 | 0.710 |
| Plasma TG, mmol/L (mean, SD) | 1.32 | 0.50 | 1.30 | 0.47 | 1.31 | 0.45 | 1.36 | 0.52 | 1.30 | 0.57 | 0.257 |
| Plasma TC, mmol/L (mean, SD) | 4.14 | 0.64 | 4.05 | 0.66 | 4.13 | 0.61 | 4.17 | 0.63 | 4.21 | 0.67 | 0.002 |
| Plasma LDL-C, mmol/L (mean, SD) | 2.05 | 0.9 | 2.03 | 0.52 | 2.05 | 0.48 | 2.06 | 0.48 | 2.04 | 0.48 | 0.932 |
| Plasma HDL-C, mmol/L (mean, SD) | 1.67 | 0.34 | 1.60 | 0.34 | 1.66 | 0.34 | 1.68 | 0.32 | 1.75 | 0.35 | <0.001 |
| GDM (N, %) | 571 | 35.3 | 118 | 28.9 | 146 | 36.1 | 151 | 37.7 | 156 | 38.6 | 0.016 |
| Eggs, number/d (mean, SD) | 0.71 | 0.58 | 0.12 | 0.21 | 0.49 | 0.29 | 0.89 | 0.31 | 1.34 | 0.56 | <0.001 |
| Red meats, g/d (mean, SD) | 59.5 | 50.5 | 39.3 | 39.0 | 59.5 | 41.7 | 61.0 | 51.1 | 78.3 | 59.7 | <0.001 |
| Poultry, g/d (mean, SD) | 12.5 | 29.2 | 6.3 | 17.7 | 11.2 | 22.4 | 13.5 | 29.2 | 19.3 | 40.8 | <0.001 |
| Fish/shellfish, g/d (mean, SD) | 18.6 | 41.8 | 6.9 | 19.3 | 14.1 | 33.5 | 17.6 | 41.6 | 35.8 | 57.8 | <0.001 |
| Total dairy products, g/d (mean, SD) | 138.5 | 132.8 | 93.8 | 116.2 | 132.6 | 129.5 | 149.4 | 124.7 | 178.7 | 145.0 | <0.001 |
| Animal organs, g/d (mean, SD) | 5.4 | 17.3 | 3.2 | 14.8 | 4.6 | 11.5 | 4.5 | 13.6 | 9.1 | 25.4 | <0.001 |
| Dietary glycaemic load, g/d (mean, SD) | 153.3 | 59.4 | 147.3 | 58.7 | 152.7 | 53.6 | 158.4 | 67.6 | 154.8 | 56.7 | 0.061 |
| Energy intake, kcal/d (mean, SD) | 1848.1 | 530.5 | 1600.1 | 486.6 | 1819.1 | 510.2 | 1901.2 | 475.4 | 2074.9 | 535.9 | <0.001 |
| Saturated fat, unsaturated fat, g/d (mean, SD) | 68.8 | 24.8 | 53.0 | 19.1 | 66.6 | 23.5 | 72.0 | 20.3 | 83.6 | 25.6 | <0.001 |
| Animal protein, g/d (mean, SD) | 25.4 | 15.4 | 12.8 | 8.2 | 22.7 | 10.4 | 27.3 | 12.2 | 39.1 | 16.4 | <0.001 |
| Fibre, g/d (mean, SD) | 12.9 | 6.3 | 11.9 | 6.5 | 12.9 | 6.7 | 13.0 | 5.8 | 13.7 | 5.9 | <0.001 |
BMI body mass index, WGPO Weight gain from pregnancy to OGTT, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, GDM gestational diabetes mellitus, MET metabolic equivalent
Associations between maternal dietary egg intake per day and GDM
| Continuous variable (each additional egg/d) | Quartile egg intake (number/d) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | ||||||||
| OR | 95%CI | OR | 95%CI | OR | 95%CI | OR | 95%CI | OR | 95%CI | ||
| Median, number/d | 0.7 | 0 | 0.5 | 1.0 | 1.3 | - | |||||
| Model 1a | 1.36 | 1.14-1.62 | 1.00 | - | 1.48 | 1.11-1.98 | 1.46 | 1.09-1.96 | 1.64 | 1.22-2.20 | 0.002 |
| Model 2b | 1.32 | 1.11-1.58 | 1.00 | - | 1.48 | 1.11-1.99 | 1.39 | 1.03-1.87 | 1.59 | 1.18-2.14 | 0.006 |
| Model 2 plus nutrientsc | |||||||||||
| Saturated fat, unsaturated fat | 1.30 | 1.08-1.56 | 1.00 | - | 1.47 | 1.09-1.97 | 1.35 | 1.00-1.84 | 1.54 | 1.13-2.09 | 0.013 |
| Animal protein | 1.33 | 1.10-1.60 | 1.00 | - | 1.48 | 1.11-1.99 | 1.39 | 1.02-1.89 | 1.59 | 1.16-2.17 | 0.008 |
| Fibre | 1.32 | 1.11-1.58 | 1.00 | - | 1.48 | 1.11-1.99 | 1.39 | 1.03-1.88 | 1.59 | 1.18-2.15 | 0.005 |
| All previous nutrients | 1.32 | 1.10-1.60 | 1.00 | - | 1.48 | 1.10-1.98 | 1.38 | 1.02-1.88 | 1.58 | 1.16-2.17 | 0.009 |
| Model 2 plus plasma lipid profiles(mmol/L) d | |||||||||||
| TG | 1.30 | 1.10-1.60 | 1.00 | - | 1.57 | 1.16-2.12 | 1.46 | 1.07-1.99 | 1.65 | 1.20-2.25 | 0.009 |
| TC | 1.31 | 1.09-1.58 | 1.00 | - | 1.61 | 1.19-2.18 | 1.45 | 1.06-1.98 | 1.64 | 1.20-2.24 | 0.011 |
| LDL-C | 1.33 | 1.11-1.60 | 1.00 | - | 1.62 | 1.20-2.19 | 1.46 | 1.07-1.99 | 1.68 | 1.23-2.30 | 0.007 |
| HDL-C | 1.31 | 1.09-1.58 | 1.00 | - | 1.60 | 1.19-2.16 | 1.44 | 1.06-1.96 | 1.64 | 1.20-2.25 | 0.011 |
| All previous measurements | 1.30 | 1.08-1.56 | 1.00 | - | 1.58 | 1.17-2.13 | 1.46 | 1.07-1.99 | 1.63 | 1.19-2.23 | 0.011 |
TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, GDM gestational diabetes mellitus
a Crude model
b Adjusted for energy intake, age, prepregnancy BMI, education, income of family, parity, family history of diabetes, smoking before pregnancy, alcohol consumption before pregnancy, physical activity, dietary glycaemic load, weight gain from pregnancy to OGTT
c Nutrients correlated with egg (saturated fat, unsaturated fat, trans fat, animal protein and fibre) were adjusted individually or in combination, in addition to Model 2 covariates
d To determine whether the effect of egg intake on GDM is related to the increase of plasma lipid profiles, the concentrations of plasma TG, TC, LDL-C and HDL-C were further adjusted individually or in combination