Literature DB >> 35258659

[Sunscreens of the future: challenges and opportunities].

Peter Wolf1, Jean Krutmann2.   

Abstract

Sunscreens provide excellent protection against erythema and against chronic damage such as photoaging and skin cancer. Today's challenges concern safety of the products and improved methods for standardizing the evaluation of their efficacy. Other important topics are the further development of sunscreen products, as well as personalization of use. Personalized sun protection based on the phenotype, the genetic profiles and moreover the skin's microbiome - all linked to the identification of certain consumer susceptibility factors - is an exciting new area of research. In particular, the expansion with innovative topical agents such as DNA repair liposomes in improved galenic formulations with UV filters tailored to the skin phototype and new topical antioxidants could in future provide even more comprehensive sun protection. New antioxidants and other agents such as nicotinamide could increase systemic photoprevention. Sustainability will also be an important aspect to protect consumers, but also the environment (i.e. especially marine wildlife) from toxic effects of sunscreens.
© 2022. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

Entities:  

Keywords:  Antioxidants; Microbiome; Personalized protection; Repair enzymes; UV filters

Mesh:

Substances:

Year:  2022        PMID: 35258659     DOI: 10.1007/s00105-022-04959-w

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  67 in total

1.  Ultraviolet radiation and cutaneous melanoma: a historical perspective.

Authors:  Philippe Autier; Jean-François Doré
Journal:  Melanoma Res       Date:  2020-04       Impact factor: 3.599

2.  Prevention of melasma relapses with sunscreen combining protection against UV and short wavelengths of visible light: a prospective randomized comparative trial.

Authors:  Fériel Boukari; Eric Jourdan; Eric Fontas; Henri Montaudié; Emeline Castela; Jean-Philippe Lacour; Thierry Passeron
Journal:  J Am Acad Dermatol       Date:  2014-10-22       Impact factor: 11.527

3.  A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention.

Authors:  Andrew C Chen; Andrew J Martin; Bonita Choy; Pablo Fernández-Peñas; Robyn A Dalziell; Catriona A McKenzie; Richard A Scolyer; Haryana M Dhillon; Janette L Vardy; Anne Kricker; Gayathri St George; Niranthari Chinniah; Gary M Halliday; Diona L Damian
Journal:  N Engl J Med       Date:  2015-10-22       Impact factor: 91.245

Review 4.  New insights in photoaging, UVA induced damage and skin types.

Authors:  Claire Battie; Setsuko Jitsukawa; Françoise Bernerd; Sandra Del Bino; Claire Marionnet; Michèle Verschoore
Journal:  Exp Dermatol       Date:  2014-10       Impact factor: 3.960

5.  Reduced number of actinic keratoses with topical application of DNA repair enzyme creams.

Authors:  Telia DeBoyes; David Kouba; David Ozog; Edgar Fincher; Lauren Moy; Kathryn Iwata; Ronald Moy
Journal:  J Drugs Dermatol       Date:  2010-12       Impact factor: 2.114

6.  Sunbeds and carcinogenesis: the need for new regulations and restrictions in Europe from the Euromelanoma perspective.

Authors:  P G Calzavara-Pinton; M Arisi; P Wolf
Journal:  J Eur Acad Dermatol Venereol       Date:  2019-03       Impact factor: 6.166

7.  Comparative Effects of Sunscreens Alone vs Sunscreens Plus DNA Repair Enzymes in Patients With Actinic Keratosis: Clinical and Molecular Findings from a 6-Month, Randomized, Clinical Study.

Authors:  Mauro Carducci; Paolo Sergio Pavone; Giuseppe De Marco; Silvia Lovati; Velimir Altabas; Karmela Altabas; Enzo Emanuele
Journal:  J Drugs Dermatol       Date:  2015-09       Impact factor: 2.114

8.  A randomized controlled trial to assess sunscreen application and beta carotene supplementation in the prevention of solar keratoses.

Authors:  Steven Darlington; Gail Williams; Rachel Neale; Christine Frost; Adèle Green
Journal:  Arch Dermatol       Date:  2003-04

9.  A method to assess the protective efficacy of sunscreens against visible light-induced pigmentation.

Authors:  Luc Duteil; Jane Esdaile; Yves Maubert; Anne-Claire Cathelineau; Anne Bouloc; Catherine Queille-Roussel; Thierry Passeron
Journal:  Photodermatol Photoimmunol Photomed       Date:  2017-06-30       Impact factor: 3.135

10.  Differences in visible light-induced pigmentation according to wavelengths: a clinical and histological study in comparison with UVB exposure.

Authors:  Luc Duteil; Nathalie Cardot-Leccia; Catherine Queille-Roussel; Yves Maubert; Yona Harmelin; Fériel Boukari; Damien Ambrosetti; Jean-Philippe Lacour; Thierry Passeron
Journal:  Pigment Cell Melanoma Res       Date:  2014-07-25       Impact factor: 4.693

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