| Literature DB >> 35256640 |
Masoud Ataei1, Xiaogang Wang2.
Abstract
We propose a novel transformation called Lehmer transform and establish a theoretical framework used to compress and characterize large volumes of highly volatile time series data. The proposed method is a powerful data-driven approach for analyzing extreme events in non-stationary and highly oscillatory stochastic processes like biological signals. The proposed Lehmer transform decomposes the information contained in a function of the data sample into a domain of some statistical moments. The mentioned statistical moments, referred to as suddencies, can be perceived as the moments that generate all possible statistics when used as inputs of the transformation. Besides, the appealing analytical properties of Lehmer transform makes it a natural candidate to take on the role of a statistic-generating function, a notion that we define in this work for the first time. Possible connections of the proposed transformation to the frequency domain will be briefly discussed, while we extensively study various aspects of developing methodologies based on the time-suddency decomposition framework. In particular, we demonstrate several superior features of the Lehmer transform over the traditional time-frequency methods such as Fourier and Wavelet transforms by analyzing the challenging electroencephalogram signals of the patients suffering from the major depressive disorder. It is shown that our proposed transformation can successfully lead to more robust and accurate classifiers developed for discerning patients from healthy controls.Entities:
Mesh:
Year: 2022 PMID: 35256640 PMCID: PMC8901916 DOI: 10.1038/s41598-022-07413-y
Source DB: PubMed Journal: Sci Rep ISSN: 2045-2322 Impact factor: 4.379
Some special cases of suddency moments.
| Suddency domain | Sample domain |
|---|---|
| Minimum ( | |
| 0 | Harmonic mean ( |
| 1/2 | Geometric mean ( |
| 1 | Arithmetic mean ( |
| 2 | Contra-harmonic mean ( |
| Maximum ( |
Figure 1Plot of raw membrane potentials against time.
Figure 2Plot of Lehmer transform against time.
Figure 3Plot of inverse Lehmer transform against time.
Figure 4Schematics of , g(y) and V(t).
Figure 5Plots of action potential distributions for some EEG signal with varying the parameters and .
Summary of missing data for MDD dataset.
| Experiment | EC | EO | TASK | Total |
|---|---|---|---|---|
| Control | 6.7% | 3.3% | 6.7% | 5.5% |
| MDD | 11.8% | 5.9% | 2.9% | 6.9% |
| Total | 9.4% | 5.0% | 5.0% | 6.3% |
Figure 6Schematics of electrode placement and action potential distributions for control and MDD subjects.
Figure 7Heat maps of the differential entropy of action potential distributions for experiments with EC.
Figure 8Heat maps of the differential entropy of action potential distributions for experiments with EO.
Figure 9Heat maps of the differential entropy of action potential distributions when performing TASK.
Comparisons with different incorporated classifiers.
| Classifier | Accuracy | Sensitivity | Specificity |
|---|---|---|---|
| Lehmer Transform + GNB | |||
| Lehmer Transform + CNN | |||
| Lehmer Transform + BADT |
Comparisons with other algorithms from literature.
| Derived EEG measure | Accuracy | Sensitivity | Specificity |
|---|---|---|---|
| ATR Index[ | |||
| EEG Theta Coherence[ | |||
| Coherence, PSD, PSD ratio[ | |||
| P300 (amplitude and latencies)[ | |||
| PSD, PSD ratios[ | |||
| Wavelet Transform[ | |||
| Lehmer Transform |
Significant values are in bold.