Literature DB >> 35254936

Multicancer Screening Tests: Anticipating And Addressing Considerations For Payer Coverage And Patient Access.

Patricia A Deverka1, Michael P Douglas2, Kathryn A Phillips3.   

Abstract

There is a tremendous public health need to identify potentially lethal cancers at earlier stages, when there is a greater chance for improved survival. Although in the US there are currently screening recommendations for only five cancers (breast, colorectal, cervical, lung, and prostate), new tests can screen for up to fifty cancers simultaneously based on a simple blood draw. However, these multicancer screening tests (also called "liquid biopsy" tests) will also present challenges to payers because of intrinsic features of the tests and the complexity of payer coverage assessments for screening tests. We describe these considerations while also offering potential solutions that can inform payers' decision making if these tests prove to be beneficial.

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Year:  2022        PMID: 35254936      PMCID: PMC8962120          DOI: 10.1377/hlthaff.2021.01316

Source DB:  PubMed          Journal:  Health Aff (Millwood)        ISSN: 0278-2715            Impact factor:   6.301


  19 in total

1.  Medicare's use of cost-effectiveness analysis for prevention (but not for treatment).

Authors:  James D Chambers; Michael J Cangelosi; Peter J Neumann
Journal:  Health Policy       Date:  2014-11-22       Impact factor: 2.980

Review 2.  Applications of liquid biopsies for cancer.

Authors:  Austin K Mattox; Chetan Bettegowda; Shibin Zhou; Nickolas Papadopoulos; Kenneth W Kinzler; Bert Vogelstein
Journal:  Sci Transl Med       Date:  2019-08-28       Impact factor: 17.956

3.  Could liquid biopsies help deliver better treatment?

Authors:  Michael Eisenstein
Journal:  Nature       Date:  2020-03       Impact factor: 49.962

4.  Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention.

Authors:  Anne Marie Lennon; Adam H Buchanan; Isaac Kinde; Andrew Warren; Ashley Honushefsky; Ariella T Cohain; David H Ledbetter; Fred Sanfilippo; Kathleen Sheridan; Dillenia Rosica; Christian S Adonizio; Hee Jung Hwang; Kamel Lahouel; Joshua D Cohen; Christopher Douville; Aalpen A Patel; Leonardo N Hagmann; David D Rolston; Nirav Malani; Shibin Zhou; Chetan Bettegowda; David L Diehl; Bobbi Urban; Christopher D Still; Lisa Kann; Julie I Woods; Zachary M Salvati; Joseph Vadakara; Rosemary Leeming; Prianka Bhattacharya; Carroll Walter; Alex Parker; Christoph Lengauer; Alison Klein; Cristian Tomasetti; Elliot K Fishman; Ralph H Hruban; Kenneth W Kinzler; Bert Vogelstein; Nickolas Papadopoulos
Journal:  Science       Date:  2020-04-28       Impact factor: 47.728

Review 5.  Liquid biopsy enters the clinic - implementation issues and future challenges.

Authors:  Michail Ignatiadis; George W Sledge; Stefanie S Jeffrey
Journal:  Nat Rev Clin Oncol       Date:  2021-01-20       Impact factor: 66.675

6.  Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA.

Authors:  M C Liu; G R Oxnard; E A Klein; C Swanton; M V Seiden
Journal:  Ann Oncol       Date:  2020-03-30       Impact factor: 32.976

7.  Complicated legacies: The human genome at 20.

Authors:  Kathryn Maxson Jones; Robert Cook-Deegan; Charles N Rotimi; Shawneequa L Callier; Amy R Bentley; Hallam Stevens; Kathryn A Phillips; Jeroen P Jansen; Christopher F Weyant; Dorothy E Roberts; Dina Zielinski; Yaniv Erlich; Nanibaa' A Garrison; Stephanie Russo Carroll; Pilar N Ossorio; Yves Moreau; Maya Wang
Journal:  Science       Date:  2021-02-04       Impact factor: 63.714

Review 8.  Universal cancer screening: revolutionary, rational, and realizable.

Authors:  David A Ahlquist
Journal:  NPJ Precis Oncol       Date:  2018-10-29

9.  Economic Impact of Coverage Expansion for Non-invasive Prenatal Testing Through a Performance-Based Risk-Sharing Agreement.

Authors:  Taryn A G Quinlan; Brock Schroeder; Sue Kwon; Jane F Barlow; Michael S Sherman; Heather D Anderson; Garth Wright; R Brett McQueen
Journal:  Pharmacoecon Open       Date:  2021-03-10

Review 10.  The dawn of the liquid biopsy in the fight against cancer.

Authors:  Irma G Domínguez-Vigil; Ana K Moreno-Martínez; Julia Y Wang; Michael H A Roehrl; Hugo A Barrera-Saldaña
Journal:  Oncotarget       Date:  2017-12-08
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