Fang Zhou1, Xiaoshi Sun1, Juan Liu2, Linlin Li3, Ling Li1, Ping Li4. 1. Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, 110022, People's Republic of China. 2. Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi 'an Jiaotong University, Xi 'an, Shanxi province, People's Republic of China. 3. Department of Academic affairs, Shenyang Open University, Shenyang, China. 4. Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, 110022, People's Republic of China. s6800@163.com.
Abstract
OBJECTIVE: To explore serum triglyceride (TG) to high-density cholesterol (HDL-C) ratio as a diagnostic marker of metabolic syndrome (MetS) in adolescents and its efficacy in predicting MetS and obesity in the early adulthood. METHODS: A stratified cluster random sampling method was used to select a total of 935 subjects from senior and junior high schools in Liaoyang, northeast China. The subjects were physically examined and laboratory evaluation was performed. A follow-up examination was performed after 5 years on some (n = 93) of the subjects who had reached adulthood. RESULTS: TG/HDL-C had significantly high diagnostic accuracy for MetS than HOMA-IR, TG or HDL-C. Subjects with the highest TG/HDL-C at baseline had higher risk of MetS (odds ratio [OR] = 11.65) and obesity (OR = 4.32) in early adulthood. CONCLUSION: TG/HDL-C ratio has a strong and independent ability in diagnosing MetS in adolescents and predicting the occurrence of MetS and obesity in their early adulthood.
OBJECTIVE: To explore serum triglyceride (TG) to high-density cholesterol (HDL-C) ratio as a diagnostic marker of metabolic syndrome (MetS) in adolescents and its efficacy in predicting MetS and obesity in the early adulthood. METHODS: A stratified cluster random sampling method was used to select a total of 935 subjects from senior and junior high schools in Liaoyang, northeast China. The subjects were physically examined and laboratory evaluation was performed. A follow-up examination was performed after 5 years on some (n = 93) of the subjects who had reached adulthood. RESULTS: TG/HDL-C had significantly high diagnostic accuracy for MetS than HOMA-IR, TG or HDL-C. Subjects with the highest TG/HDL-C at baseline had higher risk of MetS (odds ratio [OR] = 11.65) and obesity (OR = 4.32) in early adulthood. CONCLUSION: TG/HDL-C ratio has a strong and independent ability in diagnosing MetS in adolescents and predicting the occurrence of MetS and obesity in their early adulthood.
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