Literature DB >> 35250197

An evaluation of peri-operative clinical, serological and radiological parameters in hip arthroplasties -a prospective observational study of Indian cohorts.

Atul Panghate1, Abhinav D Jogani1, Sameer Panchal2, Jigar Desai1, Nandan Marathe3, Rajkumar Rathod4.   

Abstract

BACKGROUND: The scarcity of mortality data in our country led to systematic effort with aim of evaluating peri-operative parameters associated with mortality in hip arthroplasties to determine better fixation method and reducing avoidable variables. MATERIALS &
METHODS: 252 consecutive patients (133 males and 119 females; Mean age 58.68 years) operated for hip arthroplasties (cemented & uncemented THR and bipolar hemiarthroplasty) were observed prospectively for 2 years. Heart-rate, O2 saturation and BP were recorded at specific surgical steps and post-operatively for 48 h. Post-operative Trop-T and 2D Echocardiography were done in all patients and D-Dimer and CTPA in indicated ones. All post-operative deaths were extensively studied.
RESULTS: - Majority (63%) were operated for traumatic indications.48% belonged to ASA grade-1, 46% grade-2 and 4% grade-3. There was statistically significant association of diagnosis (traumatic aetiology), ASA grade 2, raised Troponin -T, raised D-dimer and pulmonary embolism with mortality. Mortality rate in our study at post-op 48 h was 5.5%, 30 day- 8% and 1-year mortality rate was 19%. With total of 14 deaths, 8 deaths (57.14%) occurred among 127 cemented arthroplasties and 6 deaths (42.86%) among 125 uncemented arthroplasties.
CONCLUSIONS: Selection of implant (cemented or uncemented) made no difference in eventual mortality. Collaborative effort of orthopaedic surgeon, anaesthetist and experts from respective fields in elderly high-risk patient with vigilant post-operative surveillance for minimum 48 h would help in lowering mortality associated with hip arthroplasties.
© 2022 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  BCIS, Bone cement implantation syndrome; Bone cement implantation syndrome; Cemented hemiarthroplasty; Mortality; Pulmonary embolism; THR, total hip replacement; Uncemented total hip replacement

Year:  2022        PMID: 35250197      PMCID: PMC8889370          DOI: 10.1016/j.jor.2022.01.009

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  19 in total

1.  Comparison of total hip replacement with and without cement in patients younger than 50 years of age: the results at 18 years.

Authors:  Y H Kim; J S Kim; J W Park; J H Joo
Journal:  J Bone Joint Surg Br       Date:  2011-04

2.  Failure rate of cemented and uncemented total hip replacements: register study of combined Nordic database of four nations.

Authors:  Keijo T Mäkelä; Markus Matilainen; Pekka Pulkkinen; Anne M Fenstad; Leif Havelin; Lars Engesaeter; Ove Furnes; Alma B Pedersen; Søren Overgaard; Johan Kärrholm; Henrik Malchau; Göran Garellick; Jonas Ranstam; Antti Eskelinen
Journal:  BMJ       Date:  2014-01-13

3.  Fat embolization and fatal cardiac arrest during hip arthroplasty with methylmethacrylate.

Authors:  K M Fallon; J G Fuller; P Morley-Forster
Journal:  Can J Anaesth       Date:  2001 Jul-Aug       Impact factor: 5.063

Review 4.  Bone cement implantation syndrome.

Authors:  A J Donaldson; H E Thomson; N J Harper; N W Kenny
Journal:  Br J Anaesth       Date:  2009-01       Impact factor: 9.166

5.  Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonary embolism in older patients: a retrospective analysis of three large cohorts.

Authors:  Renée A Douma; Grégoire le Gal; Maaike Söhne; Marc Righini; Pieter W Kamphuisen; Arnaud Perrier; Marieke J H A Kruip; Henri Bounameaux; Harry R Büller; Pierre-Marie Roy
Journal:  BMJ       Date:  2010-03-30

6.  Bone cement implantation syndrome in cemented hemiarthroplasty for femoral neck fracture: incidence, risk factors, and effect on outcome.

Authors:  F Olsen; M Kotyra; E Houltz; S-E Ricksten
Journal:  Br J Anaesth       Date:  2014-07-16       Impact factor: 9.166

7.  Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study.

Authors:  Marc Righini; Josien Van Es; Paul L Den Exter; Pierre-Marie Roy; Franck Verschuren; Alexandre Ghuysen; Olivier T Rutschmann; Olivier Sanchez; Morgan Jaffrelot; Albert Trinh-Duc; Catherine Le Gall; Farès Moustafa; Alessandra Principe; Anja A Van Houten; Marije Ten Wolde; Renée A Douma; Germa Hazelaar; Petra M G Erkens; Klaas W Van Kralingen; Marco J J H Grootenboers; Marc F Durian; Y Whitney Cheung; Guy Meyer; Henri Bounameaux; Menno V Huisman; Pieter W Kamphuisen; Grégoire Le Gal
Journal:  JAMA       Date:  2014-03-19       Impact factor: 56.272

8.  Perioperative mortality after hemiarthroplasty related to fixation method.

Authors:  Darren J Costain; Sarah L Whitehouse; Nicole L Pratt; Stephen E Graves; Philip Ryan; Ross W Crawford
Journal:  Acta Orthop       Date:  2011-05-11       Impact factor: 3.717

9.  Cemented versus uncemented fixation in total hip replacement: a systematic review and meta-analysis of randomized controlled trials.

Authors:  Ali Abdulkarim; Prasad Ellanti; Nicola Motterlini; Tom Fahey; John M O'Byrne
Journal:  Orthop Rev (Pavia)       Date:  2013-03-15

10.  Mortality after total hip replacement surgery: A systematic review.

Authors:  J R Berstock; A D Beswick; E Lenguerrand; M R Whitehouse; A W Blom
Journal:  Bone Joint Res       Date:  2014-06       Impact factor: 5.853

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