Literature DB >> 35246987

FcεRI- and MRGPRX2-evoked acute degranulation responses are fully additive in human skin mast cells.

Magda Babina1,2,3, Zhao Wang1,2,4, Zhuoran Li1,2,3, Kristin Franke1,2,3, Sven Guhl1,2,3, Metin Artuc1,2,3, Torsten Zuberbier1,2,3.   

Abstract

Entities:  

Keywords:  FcεRI; MRGPRX2; anaphylaxis; drug allergy; mast cell

Mesh:

Substances:

Year:  2022        PMID: 35246987     DOI: 10.1111/all.15270

Source DB:  PubMed          Journal:  Allergy        ISSN: 0105-4538            Impact factor:   13.146


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  3 in total

1.  The Number of MRGPRX2-Expressing Cells Is Increased in Skin Lesions of Patients With Indolent Systemic Mastocytosis, But Is Not Linked to Symptom Severity.

Authors:  Polina Pyatilova; Tameem Ashry; Yanyan Luo; Jiajun He; Hanna Bonnekoh; Qingqing Jiao; Sherezade Moñino-Romero; Man Hu; Jörg Scheffel; Stefan Frischbutter; Maud A W Hermans; Bradford A Youngblood; Marcus Maurer; Frank Siebenhaar; Pavel Kolkhir
Journal:  Front Immunol       Date:  2022-07-26       Impact factor: 8.786

2.  β-arrestin-1 and β-arrestin-2 Restrain MRGPRX2-Triggered Degranulation and ERK1/2 Activation in Human Skin Mast Cells.

Authors:  Zhao Wang; Zhuoran Li; Gürkan Bal; Kristin Franke; Torsten Zuberbier; Magda Babina
Journal:  Front Allergy       Date:  2022-07-15

3.  MRGPRX2-Mediated Degranulation of Human Skin Mast Cells Requires the Operation of Gαi, Gαq, Ca++ Channels, ERK1/2 and PI3K-Interconnection between Early and Late Signaling.

Authors:  Zhao Wang; Kristin Franke; Gürkan Bal; Zhuoran Li; Torsten Zuberbier; Magda Babina
Journal:  Cells       Date:  2022-03-10       Impact factor: 6.600

  3 in total

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