Literature DB >> 3524648

The effect of zaprinast (M&B 22,948, an orally absorbed mast cell stabilizer) on exercise-induced asthma in children.

J Reiser, Y Yeang, J O Warner.   

Abstract

We conducted a placebo controlled, double-blind trial on the effect of a single dose of zaprinast (M&B 22,948, an orally active mast cell stabilizer) on exercise-induced asthma in 15 children. We demonstrated no prophylactic effect on the whole group. A trend towards effectiveness was shown when the results for children whose asthma was not steroid dependent were analysed alone.

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Year:  1986        PMID: 3524648     DOI: 10.1016/0007-0971(86)90036-7

Source DB:  PubMed          Journal:  Br J Dis Chest        ISSN: 0007-0971


  2 in total

Review 1.  Phosphodiesterase inhibitors: new opportunities for the treatment of asthma.

Authors:  T J Torphy; B J Undem
Journal:  Thorax       Date:  1991-07       Impact factor: 9.139

2.  Effect of selective phosphodiesterase 3 inhibition on the early and late asthmatic responses to inhaled allergen.

Authors:  P G Bardin; M A Dorward; F C Lampe; B Franke; S T Holgate
Journal:  Br J Clin Pharmacol       Date:  1998-04       Impact factor: 4.335

  2 in total

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