| Literature DB >> 3524588 |
Abstract
Bezafibrate was given to 23 hypertriglyceridemic but otherwise healthy middle-aged men in a double-blind, cross-over study to evaluate its effect on the components of the fibrinolytic system as well as on ATIII, FVIIIR: Ag, FVIII: C and platelet aggregation. Fibrinogen dropped markedly (P less than 0.05) and there was a small but significant fall of ATIII. The second wave of platelet aggregation was found much less frequently than in controls (P less than 0.001). Bezafibrate seemed to decrease the rate of formation of the first wave platelet aggregation.Entities:
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Year: 1986 PMID： 3524588 DOI： 10.1016/0021-9150(86)90116-4
Source DB: PubMed Journal: Atherosclerosis ISSN： 0021-9150 Impact factor: 5.162