Literature DB >> 3524323

Alkaline ingestions.

J M Howell.   

Abstract

Alkaline ingestion is a potentially life-threatening problem that may confront the emergency physician. It is similar to many other toxins in that children and those who attempt suicide are its most common victims; however, implications in terms of initial stabilization and definitive care are quite distinct. Mucosal exposure to lye results in a quick, deep liquefactive necrosis. Consequently, blind nasotracheal intubation may result in the perforation of damaged tissues in the pharynx and trachea. For similar reasons, the blind passage of a nasogastric tube is contraindicated. The use of diluents in this setting is controversial. If a diluent is used, water and milk are considered the liquids of choice. They may be used to irrigate oropharyngeal burns, but are contraindicated in the face of respiratory compromise, shock, liquid lye ingestion, and perforation of the esophagus or stomach. Cathartics and charcoal are not used after alkaline ingestion. Cathartics, however, are used in miniature alkaline battery ingestions to diminish bowel transit time. Esophagoscopy should be done within 12 to 24 hours after ingestion to directly observe the extent of damage. This procedure should be stopped at the first sign of injury to protect against iatrogenic esophageal perforation. Steroids should be started for circumferential esophageal burns and in those patients with significant injury who are unable to undergo esophagoscopy. IV antibiotics are administered for gastrointestinal perforation and may be used concomitantly with steroids. Miniature alkaline batteries lodged in the esophagus must be removed immediately. The available modalities include fluoroscopy-directed Foley catheter removal, endoscopy, and surgery.(ABSTRACT TRUNCATED AT 250 WORDS)

Entities:  

Mesh:

Substances:

Year:  1986        PMID: 3524323     DOI: 10.1016/s0196-0644(86)80382-1

Source DB:  PubMed          Journal:  Ann Emerg Med        ISSN: 0196-0644            Impact factor:   5.721


  8 in total

1.  A novel approach for preventing esophageal stricture formation: sphingosylphosphorylcholine-enhanced tissue remodeling.

Authors:  Aydin Yagmurlu; Burhan Aksu; Meltem Bingol-Kologlu; Nurten Renda; Gulcin Altinok; Suat Fitoz; I Haluk Gokcora; Huseyin Dindar
Journal:  Pediatr Surg Int       Date:  2004-10       Impact factor: 1.827

2.  Macroscopic and histopathological aspects of chemical damage to human tissues depending on the survival time.

Authors:  Alberto Amadasi; Guendalina Gentile; Alessandra Rancati; Riccardo Zoja
Journal:  Int J Legal Med       Date:  2015-09-18       Impact factor: 2.686

3.  Corrosive injury of upper gastrointestinal tract by calcium oxide.

Authors:  Mihoko Yoshida; Yosuke Matsumoto; Takanobu Suzuki; Satoshi Nishimura; Takahiro Kato; Kazuho Shimura; Hiroto Kaneko; Masafumi Taniwaki
Journal:  Indian J Gastroenterol       Date:  2019-10

4.  Systemic and local effects of long-term exposure to alkaline drinking water in rats.

Authors:  M E Merne; K J Syrjänen; S M Syrjänen
Journal:  Int J Exp Pathol       Date:  2001-08       Impact factor: 1.925

5.  Perioperative management of paediatric microstomia.

Authors:  J H Diaz; J L Guarisco; F E LeJeune
Journal:  Can J Anaesth       Date:  1991-03       Impact factor: 5.063

6.  A complicated hospitalization following dilute ammonium chloride ingestion.

Authors:  Kendra Hammond; Tiffany Graybill; Susannah E Speiss; Jenny Lu; Jerrold B Leikin
Journal:  J Med Toxicol       Date:  2009-12

7.  Critical pH level of lye (NaOH) for esophageal injury.

Authors:  Ozlen Atug; Ahmet Dobrucali; Roy Charles Orlando
Journal:  Dig Dis Sci       Date:  2009-03-07       Impact factor: 3.199

8.  Intraoral chemical burn in an elderly patient with dementia.

Authors:  Takuya Naganawa; Hidemasa Murozumi; Abhishek Kumar; Atsushi Okuyama; Toshihiro Okamoto; Tomohiro Ando
Journal:  Int J Burns Trauma       Date:  2015-10-12
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.