Andrés Reyes-Campo1, Sara G Pacichana-Quinayás1,2, Annora A Kumar3, Luz M Leiva-Pemberthy1, Maria A Tovar-Sánchez1, Francisco J Bonilla-Escobar4,5,6. 1. Departamento de Medicina Física y Rehabilitación, Grupo de Investigación en Rehabilitación de la Universidad del Valle (GIRUV), Universidad del Valle; Hospital Universitario del Valle, "Evaristo Garcia" E.S.E., Cali, Colombia. 2. Fundación Somos Ciencia al Servicio de la Comunidad, Fundación SCISCO/Science to Serve the Community Foundation, SCISCO Foundation, Cali, Colombia. 3. UWA Medical School, The University of Western Australia, Nedlands, WA, Australia. 4. Departamento de Medicina Física y Rehabilitación, Grupo de Investigación en Rehabilitación de la Universidad del Valle (GIRUV), Universidad del Valle; Hospital Universitario del Valle, "Evaristo Garcia" E.S.E., Cali, Colombia. francisco.bonilla@correounivalle.edu.co. 5. Fundación Somos Ciencia al Servicio de la Comunidad, Fundación SCISCO/Science to Serve the Community Foundation, SCISCO Foundation, Cali, Colombia. francisco.bonilla@correounivalle.edu.co. 6. University of Pittsburgh, Institute for Clinical Research Education ICRE, Pittsburgh, PA, USA. francisco.bonilla@correounivalle.edu.co.
Abstract
STUDY DESIGN: Case-control study. OBJECTIVES: To identify factors associated with neuropathic pain (NP) in patients with spinal cord injury of traumatic origin (TSCI). SETTING: University Hospital of Valle, Cali, Colombia. METHODS: Study participants were individuals with diagnosis of TSCI who visited a trauma referral center from January 1st, 2016, to December 31st, 2016. Information was retrospectively extracted from the Hospital's Spinal Cord Injury registry and patients' medical records. Cases were defined as patients with NP and controls were those without NP. The exposure of interest was intentional injuries. Individuals were matched by age and stratified into 11 groups of ±3 years each. RESULTS: We found 164 participants with an average age of 34 ± 13 years, of whom 95.1% were male, and 53.6% had NP. Neurogenic bladder and bowel occurred in 94.3% of NP patients. Cause of injury was not associated with NP. Older injuries were protective for NP (>10 years since injury OR = 0.10, 95% CI = 0.03-0.37, p < 0.0001) and neurogenic bladder and bowel were found as risk factors (OR = 5.89, 95% CI = 1.84-18.88; p = 0.003). CONCLUSIONS: Our study uniquely shows time since injury as a protective factor for NP and neurogenic bladder and bowel as a risk factor, while violence was not found associated. This could help guide the scope of future research about NP secondary to SCI.
STUDY DESIGN: Case-control study. OBJECTIVES: To identify factors associated with neuropathic pain (NP) in patients with spinal cord injury of traumatic origin (TSCI). SETTING: University Hospital of Valle, Cali, Colombia. METHODS: Study participants were individuals with diagnosis of TSCI who visited a trauma referral center from January 1st, 2016, to December 31st, 2016. Information was retrospectively extracted from the Hospital's Spinal Cord Injury registry and patients' medical records. Cases were defined as patients with NP and controls were those without NP. The exposure of interest was intentional injuries. Individuals were matched by age and stratified into 11 groups of ±3 years each. RESULTS: We found 164 participants with an average age of 34 ± 13 years, of whom 95.1% were male, and 53.6% had NP. Neurogenic bladder and bowel occurred in 94.3% of NP patients. Cause of injury was not associated with NP. Older injuries were protective for NP (>10 years since injury OR = 0.10, 95% CI = 0.03-0.37, p < 0.0001) and neurogenic bladder and bowel were found as risk factors (OR = 5.89, 95% CI = 1.84-18.88; p = 0.003). CONCLUSIONS: Our study uniquely shows time since injury as a protective factor for NP and neurogenic bladder and bowel as a risk factor, while violence was not found associated. This could help guide the scope of future research about NP secondary to SCI.
Authors: T N Bryce; F Biering-Sørensen; N B Finnerup; D D Cardenas; R Defrin; T Lundeberg; C Norrbrink; J S Richards; P Siddall; T Stripling; R-D Treede; S G Waxman; E Widerström-Noga; R P Yezierski; M Dijkers Journal: Spinal Cord Date: 2011-12-20 Impact factor: 2.772
Authors: N Nagoshi; S Kaneko; K Fujiyoshi; M Takemitsu; M Yagi; S Iizuka; A Miyake; A Hasegawa; M Machida; T Konomi; M Machida; T Asazuma; M Nakamura Journal: Spinal Cord Date: 2015-12-01 Impact factor: 2.772
Authors: Andrés Reyes Campo; Sara Gabriela Pacichana-Quinayáz; Francisco Javier Bonilla-Escobar; Luz Miriam Leiva-Pemberthy; Maria Ana Tovar-Sánchez; Olga Marina Hernández-Orobio; Gloria-Patricia Arango-Hoyos; Adnan Mujanovic Journal: JMIR Res Protoc Date: 2022-04-29