Literature DB >> 35237989

Monitoring Atheroprotective Macrophage Cholesterol Efflux In Vivo.

Andrea Rivas-Urbina1, Noemi Rotllan1,2, David Santos1,2, Josep Julve1,2,3, Jose Luis Sanchez-Quesada4,5,6, Joan Carles Escolà-Gil7,8,9.   

Abstract

This chapter provides details on the methodologies currently used to monitor macrophage cholesterol efflux in vivo in mice. The general principles and techniques described herein can be applied to evaluate the effect of different experimental pathophysiological conditions or the efficacy of different therapeutic strategies on the modulation of in vivo cholesterol efflux to plasma acceptors and the rate of reverse transport of unesterified cholesterol from macrophages to feces in mice.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Cholesterol; Cholesterol efflux; HDL; Macrophage; Method; Reverse cholesterol transport

Mesh:

Substances:

Year:  2022        PMID: 35237989     DOI: 10.1007/978-1-0716-1924-7_35

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  5 in total

1.  LDL Receptor Regulates the Reverse Transport of Macrophage-Derived Unesterified Cholesterol via Concerted Action of the HDL-LDL Axis: Insight From Mouse Models.

Authors:  Miriam Lee-Rueckert; Francisco Blanco-Vaca; Joan Carles Escolà-Gil; Lídia Cedó; Jari Metso; David Santos; Annabel García-León; Núria Plana; Sonia Sabate-Soler; Noemí Rotllan; Andrea Rivas-Urbina; Karen A Méndez-Lara; Mireia Tondo; Josefa Girona; Josep Julve; Victor Pallarès; Aleyda Benitez-Amaro; Vicenta Llorente-Cortes; Antonio Pérez; Diego Gómez-Coronado; Anna-Kaisa Ruotsalainen; Anna-Liisa Levonen; José Luis Sanchez-Quesada; Luís Masana; Petri T Kovanen; Matti Jauhiainen
Journal:  Circ Res       Date:  2020-06-04       Impact factor: 17.367

Review 2.  High-Density Lipoprotein Function in Cardiovascular Disease and Diabetes Mellitus.

Authors:  Yi He; Vishal Kothari; Karin E Bornfeldt
Journal:  Arterioscler Thromb Vasc Biol       Date:  2018-02       Impact factor: 8.311

Review 3.  HDL and Reverse Cholesterol Transport.

Authors:  Mireille Ouimet; Tessa J Barrett; Edward A Fisher
Journal:  Circ Res       Date:  2019-05-10       Impact factor: 17.367

Review 4.  HDL functionality in reverse cholesterol transport--Challenges in translating data emerging from mouse models to human disease.

Authors:  Miriam Lee-Rueckert; Joan Carles Escola-Gil; Petri T Kovanen
Journal:  Biochim Biophys Acta       Date:  2016-03-09

5.  Overexpression of apolipoprotein A-I promotes reverse transport of cholesterol from macrophages to feces in vivo.

Authors:  YuZhen Zhang; Ilaria Zanotti; Muredach P Reilly; Jane M Glick; George H Rothblat; Daniel J Rader
Journal:  Circulation       Date:  2003-08-04       Impact factor: 29.690

  5 in total
  1 in total

Review 1.  HDL as Bidirectional Lipid Vectors: Time for New Paradigms.

Authors:  María Luna-Luna; Eric Niesor; Óscar Pérez-Méndez
Journal:  Biomedicines       Date:  2022-05-20
  1 in total

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