Literature DB >> 35236938

Revealing the secret behind Smo cholesterylation.

Yuhong Han1, Jin Jiang2,3.   

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Year:  2022        PMID： 35236938      PMCID： PMC8975896          DOI： 10.1038/s41422-022-00636-8

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   46.297


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  8 in total

1.  Structural Basis of Smoothened Activation in Hedgehog Signaling.

Authors:  Pengxiang Huang; Sanduo Zheng; Bradley M Wierbowski; Youngchang Kim; Daniel Nedelcu; Laura Aravena; Jing Liu; Andrew C Kruse; Adrian Salic
Journal:  Cell       Date:  2018-05-24       Impact factor: 41.582

2.  Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.

Authors:  Xu Xiao; Jing-Jie Tang; Chao Peng; Yan Wang; Lin Fu; Zhi-Ping Qiu; Yue Xiong; Lian-Fang Yang; Hai-Wei Cui; Xiao-Long He; Lei Yin; Wei Qi; Catherine C L Wong; Yun Zhao; Bo-Liang Li; Wen-Wei Qiu; Bao-Liang Song
Journal:  Mol Cell       Date:  2017-03-23       Impact factor: 17.970

3.  Cilia-Associated Oxysterols Activate Smoothened.

Authors:  David R Raleigh; Navdar Sever; Pervinder K Choksi; Monika Abedin Sigg; Kelly M Hines; Bonne M Thompson; Daniel Elnatan; Priyadarshini Jaishankar; Paola Bisignano; Francesc R Garcia-Gonzalo; Alexis Leigh Krup; Markus Eberl; Eamon F X Byrne; Christian Siebold; Sunny Y Wong; Adam R Renslo; Michael Grabe; Jeffrey G McDonald; Libin Xu; Philip A Beachy; Jeremy F Reiter
Journal:  Mol Cell       Date:  2018-10-18       Impact factor: 17.970

4.  Patched acts catalytically to suppress the activity of Smoothened.

Authors:  J Taipale; M K Cooper; T Maiti; P A Beachy
Journal:  Nature       Date:  2002-08-22       Impact factor: 49.962

5.  Smoothened stimulation by membrane sterols drives Hedgehog pathway activity.

Authors:  Ishan Deshpande; Jiahao Liang; Danielle Hedeen; Kelsey J Roberts; Yunxiao Zhang; Betty Ha; Naomi R Latorraca; Bryan Faust; Ron O Dror; Philip A Beachy; Benjamin R Myers; Aashish Manglik
Journal:  Nature       Date:  2019-07-01       Impact factor: 49.962

6.  Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi.

Authors:  Xiaofeng Qi; Heng Liu; Bonne Thompson; Jeffrey McDonald; Cheng Zhang; Xiaochun Li
Journal:  Nature       Date:  2019-06-05       Impact factor: 49.962

7.  Structural basis of Smoothened regulation by its extracellular domains.

Authors:  Eamon F X Byrne; Ria Sircar; Simon Newstead; Paul S Miller; George Hedger; Giovanni Luchetti; Sigrid Nachtergaele; Mark D Tully; Laurel Mydock-McGrane; Douglas F Covey; Robert P Rambo; Mark S P Sansom; Rajat Rohatgi; Christian Siebold
Journal:  Nature       Date:  2016-07-20       Impact factor: 49.962

8.  Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling.

Authors:  Xiaofeng Qi; Lucas Friedberg; Ryan De Bose-Boyd; Tao Long; Xiaochun Li
Journal:  Nat Chem Biol       Date:  2020-09-14       Impact factor: 15.040
  8 in total

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