| Literature DB >> 35230686 |
Rosaria Valentina Rapicavoli1,2, Salvatore Alaimo2, Alfredo Ferro2, Alfredo Pulvirenti3.
Abstract
The wealth of knowledge and multi-omics data available in drug research has allowed the rise of several computational methods in the drug discovery field, resulting in a novel and exciting strategy called drug repurposing. Drug repurposing consists in finding new applications for existing drugs. Numerous computational methods perform a high-level integration of different knowledge sources to facilitate the discovery of unknown mechanisms. In this chapter, we present a survey of data resources and computational tools available for drug repositioning.Entities:
Keywords: 3D structures; Biological pathways; Drug databases; Drug repositioning; Drug-target interaction prediction; Gene expression; Ligand similarity
Mesh:
Year: 2022 PMID: 35230686 DOI: 10.1007/978-3-030-91836-1_7
Source DB: PubMed Journal: Adv Exp Med Biol ISSN: 0065-2598 Impact factor: 2.622