Literature DB >> 35228945

Methanol Intoxication Presenting With Bilateral Optic Neuritis and Paracentral Acute Middle Maculopathy.

Sherouk G Saad1, Yousef A Fouad2, Mohamed Nowara1.   

Abstract

A 52-year-old male presented nine days following accidental methanol ingestion with a drop of vision in both eyes. A complete ophthalmic assessment was performed, with a referral to a neurologist for multidisciplinary management. On ophthalmological evaluation, visual acuity was hand motion (HM) bilaterally with swollen optic discs. Macular optical coherence tomography (OCT) showed a picture consistent with paracentral acute middle maculopathy (PAMM) in both eyes, and brain magnetic resonance imaging showed ischemic insults. Slight visual improvement was detected following steroid and antiplatelet therapy. At two months of follow-up, bilateral optic atrophy ensued. Special attention must be given to the macular assessment and not just the optic nerve when considering a case of methanol toxicity, as methanol intoxication can lead to ischemic manifestations.
Copyright © 2022, Saad et al.

Entities:  

Keywords:  methanol; optic neuritis; optical coherence tomography; paracentral acute middle maculopathy; toxic optic neuropathy

Year:  2022        PMID: 35228945      PMCID: PMC8873372          DOI: 10.7759/cureus.21587

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  8 in total

Review 1.  Paracentral Acute Middle Maculopathy: What We Knew Then and What We Know Now.

Authors:  Ehsan Rahimy; Laura Kuehlewein; Srinivas R Sadda; David Sarraf
Journal:  Retina       Date:  2015-10       Impact factor: 4.256

2.  A case of optic nerve atrophy with severe disc cupping after methanol poisoning.

Authors:  Yong Woon Shin; Ki Bang Uhm
Journal:  Korean J Ophthalmol       Date:  2011-03-11

3.  Optical Coherence Tomography Angiography and En Face Optical Coherence Tomography Features of Paracentral Acute Middle Maculopathy.

Authors:  Jayanth Sridhar; Abtin Shahlaee; Ehsan Rahimy; Bryan K Hong; M Ali Khan; Joseph I Maguire; James P Dunn; Sonia Mehta; Allen C Ho
Journal:  Am J Ophthalmol       Date:  2015-09-18       Impact factor: 5.258

4.  An unusual case of bilateral multifocal retinal pigment epithelial detachment with methanol-induced optic neuritis.

Authors:  Ratnesh Ranjan; Rajnath Kushwaha; Ramesh Chandra Gupta; Perwez Khan
Journal:  J Med Toxicol       Date:  2014-03

5.  Multimodal imaging findings in retinal deep capillary ischemia.

Authors:  Suqin Yu; Fenghua Wang; Claudine E Pang; Lawrence A Yannuzzi; K Bailey Freund
Journal:  Retina       Date:  2014-04       Impact factor: 4.256

Review 6.  Paracentral acute middle maculopathy and the organization of the retinal capillary plexuses.

Authors:  Jackson Scharf; K Bailey Freund; SriniVas Sadda; David Sarraf
Journal:  Prog Retin Eye Res       Date:  2020-08-09       Impact factor: 21.198

7.  Optical coherence tomography findings in methanol toxicity.

Authors:  Kendra A Klein; Alexis K Warren; Caroline R Baumal; Thomas R Hedges
Journal:  Int J Retina Vitreous       Date:  2017-09-25
  8 in total

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