Literature DB >> 35227050

Assessment of the Appropriateness of Prescriptions in a Geriatric Outpatient Clinic

Burcu Kelleci Çakır1, Muhammet Cemal Kızılarslanoğlu2, Mustafa Kemal Kılıç2, Rana Tuna Doğrul2, Mehmet Emin Kuyumcu2, Aygin Bayraktar Ekincioğlu1, Merve Başol3, Meltem Halil2, Kutay Demirkan1.   

Abstract

Objectives: Appropriateness of the geriatric outpatients' medications needs special attention due to risks of falls, fractures, depression, hospital admissions and mortality. This study aimed to identify current practice on medication usage by using the 2nd version of "Screening Tool of Older People's Potentially Inappropriate Prescriptions" and "Screening Tool to Alert Doctors to Right Treatment" criteria and affecting factors for the Turkish population. Materials and
Methods: This cross-sectional study was conducted between September 2015 and May 2016 at a university research and training hospital's geriatric outpatient clinic. Patients aged ≥65 years and had ≥5 different prescribed medications (considered as polypharmacy) were recruited. The main outcome measure was the frequency of inappropriate medications identified by clinical pharmacist in the outpatient clinic according to the 2nd version of the criterion sets.
Results: A total of 700 patients (440 female) were included in this study. According to the results, 316 patients (45.1%) with at least one potentially inappropriate medication and 668 patients (98.3%) with at least one potential prescription omission were detected. Potentially inappropriate medications were associated with the number of medications used per patient [odds ratio (OR): 1.20 p<0.001], living alone (OR: 4.12 p=0.02), and having congestive heart failure (OR: 2.41 p<0.001). Twenty-two (27.5%) out of 80 criteria and 4 (11.8%) out of 34 criteria did not apply to the study population.
Conclusion: Detecting inappropriate medications to maintain treatment effectiveness is necessary to provide the optimum therapy. Despite the awareness of polypharmacy in outpatient clinics it is still one of the important causes of inappropriate prescription followed by vaccination rate. Therefore, with the contribution of clinical pharmacist using these available criteria is important, moreover modification of these criteria according to the local needs to be considered to achieve better outcomes.

Entities:  

Keywords:  Clinical pharmacist; STOPP/START criteria; older adults; outpatients; polypharmacy

Year:  2022        PMID: 35227050      PMCID: PMC8892563          DOI: 10.4274/tjps.galenos.2021.77010

Source DB:  PubMed          Journal:  Turk J Pharm Sci        ISSN: 1304-530X


  30 in total

1.  Study of pharmacist intervention in polypharmacy among older patients: Non-randomized, controlled trial.

Authors:  Ryota Hashimoto; Keiko Fujii; Shizuka Shimoji; Atsuyuki Utsumi; Kazutaka Hosokawa; Hiroki Tochino; Shigeki Sanehisa; Masahiro Akishita; Mitsuko Onda
Journal:  Geriatr Gerontol Int       Date:  2019-12-20       Impact factor: 2.730

2.  STOPP/START version 2-development of software applications: easier said than done?

Authors:  Pauline Anrys; Benoît Boland; Jean-Marie Degryse; Jan De Lepeleire; Mirko Petrovic; Sophie Marien; Olivia Dalleur; Goedele Strauven; Veerle Foulon; Anne Spinewine
Journal:  Age Ageing       Date:  2016-07-04       Impact factor: 10.668

3.  Potentially inappropriate prescribing (IP) for elderly medical inpatients in Taiwan: a hospital-based study.

Authors:  Chien-Liang Liu; Li-Ning Peng; Yi-Tsun Chen; Ming-Hsien Lin; Li-Kuo Liu; Liang-Kung Chen
Journal:  Arch Gerontol Geriatr       Date:  2011-08-05       Impact factor: 3.250

4.  Potentially inappropriate prescribing according to the STOPP/START criteria for older adults.

Authors:  Özgür Kara; Güneş Arık; Muhammet Cemal Kızılarslanoglu; Mustafa Kemal Kılıc; Hacer Dogan Varan; Fatih Sümer; Mert Esme; Seda Altıner; Mehmet Emin Kuyumcu; Yusuf Yesil; Burcu Balam Yavuz; Mustafa Cankurtaran; Meltem Halil
Journal:  Aging Clin Exp Res       Date:  2015-12-11       Impact factor: 3.636

5.  Inappropriate prescribing to the oldest old patients admitted to hospital: prevalence, most frequently used medicines, and associated factors.

Authors:  Antonio San-José; Antonia Agustí; Xavier Vidal; Francesc Formiga; Mercedes Gómez-Hernández; Juana García; Alfonso López-Soto; Nieves Ramírez-Duque; Olga H Torres; José Barbé
Journal:  BMC Geriatr       Date:  2015-04-09       Impact factor: 3.921

Review 6.  STOPP/START criteria for potentially inappropriate prescribing in older people: version 2.

Authors:  Denis O'Mahony; David O'Sullivan; Stephen Byrne; Marie Noelle O'Connor; Cristin Ryan; Paul Gallagher
Journal:  Age Ageing       Date:  2014-10-16       Impact factor: 10.668

7.  Development of a Whole-Body Physiologically Based Pharmacokinetic Approach to Assess the Pharmacokinetics of Drugs in Elderly Individuals.

Authors:  Jan-Frederik Schlender; Michaela Meyer; Kirstin Thelen; Markus Krauss; Stefan Willmann; Thomas Eissing; Ulrich Jaehde
Journal:  Clin Pharmacokinet       Date:  2016-12       Impact factor: 6.447

8.  Prevalence of potentially inappropriate medications use among older adults and risk factors using the 2015 American Geriatrics Society Beers criteria.

Authors:  Tariq M Alhawassi; Wafa Alatawi; Monira Alwhaibi
Journal:  BMC Geriatr       Date:  2019-05-29       Impact factor: 3.921

9.  Potentially inappropriate medications prescribing according to Beers criteria among elderly outpatients in Jordan: a cross sectional study.

Authors:  Ahmad Al-Azayzih; Rawan Alamoori; Shoroq M Altawalbeh
Journal:  Pharm Pract (Granada)       Date:  2019-06-05

10.  Turkish inappropriate medication use in the elderly (TIME) criteria to improve prescribing in older adults: TIME-to-STOP/TIME-to-START.

Authors:  Gulistan Bahat; Birkan Ilhan; Tugba Erdogan; Meltem Halil; Sumru Savas; Zekeriya Ulger; Filiz Akyuz; Ahmet Kaya Bilge; Sibel Cakir; Kutay Demirkan; Mustafa Erelel; Kerim Guler; Hasmet Hanagasi; Belgin Izgi; Ates Kadioglu; Ayse Karan; Isin Baral Kulaksizoglu; Ali Mert; Savas Ozturk; Ilhan Satman; Mehmet Sukru Sever; Tufan Tukek; Yagiz Uresin; Onay Yalcin; Nilufer Yesilot; Meryem Merve Oren; Mehmet Akif Karan
Journal:  Eur Geriatr Med       Date:  2020-03-05       Impact factor: 1.710

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Authors:  Denise J van der Nat; Victor J B Huiskes; Aatke van der Maas; Judith Y M N Derijks-Engwegen; Hein A W van Onzenoort; Bart J F van den Bemt
Journal:  BMC Health Serv Res       Date:  2022-08-05       Impact factor: 2.908

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