| Literature DB >> 35223431 |
Ronja Christensen1,2, Corinna Haenschel1, Sebastian B Gaigg1, Anne-Kathrin J Fett1,2.
Abstract
Loneliness is common in psychosis and occurs along a continuum. Here we investigate inter-relationships between loneliness, three-dimensional schizotypy, and depressive symptoms before and during the COVID-19 pandemic. The sample included 507 university students (48.3% participated before and 51.7% during the COVID-19 pandemic) who completed the Multidimensional Schizotypy Scale-Brief, the Counseling Center Assessment of Psychological Symptoms depression scale and the University of California, Los Angeles Loneliness Scale. Schizotypy and depression scores were regressed onto loneliness individually and in multiple regressions. The cohorts did not differ in any of the schizotypy domains (all p > .29). Depressive symptoms (p = .05) and loneliness (p = .006) were higher during the pandemic than before. Across cohorts, loneliness was significantly associated with positive (β = 0.23, p < .001), negative (β = 0.44, p < .001), and disorganised schizotypy (β = 0.44, p < .001), and with depression (β = 0.72, p < .001). Schizotypy together explained a significant amount of variance in loneliness (R2 = 0.26), with significant associations with positive (β = -0.09, p = .047), negative (β = 0.31, p < .001) and disorganised schizotypy (β = 0.34, p < .001). When depression was included (β = 0.69, p < .001), only positive (β = -0.09, p = .008) and negative schizotypy (β = 0.22, p < .001) significantly predicted loneliness. When all schizotypy dimensions and depression were considered together, only negative schizotypy and depression significantly predicted loneliness. Loneliness and depressive symptoms were higher during the pandemic, but this did not relate to cohort differences in schizotypy.Entities:
Keywords: COVID-19; Depression; Loneliness; Psychosis continuum; Schizotypy
Year: 2022 PMID: 35223431 PMCID: PMC8860670 DOI: 10.1016/j.scog.2022.100243
Source DB: PubMed Journal: Schizophr Res Cogn ISSN: 2215-0013
Participant characteristics.
| Pre-COVID-19 Cohort ( | During COVID-19 Cohort ( | Combined cohorts | |
|---|---|---|---|
| Age, mean (SD) [range] | 19.92 (4.53) [18–50] | 19.71 (3.43) [17–54] | 19.75 (3.62) [17–54] |
| Gender ( | |||
| Female | 220 (89.8%) | 238 (90.8%) | 458 (90.3%) |
| Male | 24 (9.8%) | 23 (8.8%) | 47 (9.3%) |
| Other | 1 (0.4%) | 1 (0.4%) | 2 (0.4%) |
| Ethnicity, | |||
| Black/Black British | 20 (8.2%) | 20 (7.6%) | 40 (7.9%) |
| Asian/Asian British | 103 (42.2%) | 114 (43.5%) | 217 (42.9%) |
| White/White British | 85 (34.8%) | 82 (31.3%) | 167 (33.0%) |
| Mixed/other/prefer not to say | 37 (15.1%) | 46 (17.5%) | 82 (16.2%) |
| UCLA loneliness, mean (SD) [range] | 41.26 (0.10) [22–73] | 43.84 (10.37) [22-73] | 42.59 (10.5) [22–73] |
| MSS-B, mean (SD) [range] | |||
| Positive schizotypy | 3.02 (2.98) | 3.29 (2.86) | 3.16 (2.92) [0−13] |
| Negative schizotypy | 2.83 (2.65) | 3.07 (2.66) | 2.96 (2.66) [0−12] |
| Disorganised schizotypy | 3.29 (3.61) | 3.48 (3.50) | 3.39 (3.56) [0–12] |
| CCAPS-62 depression, mean (SD) [range] | 1.48 (0.91) | 1.64 (0.90) | 1.57 (0.91) [0–3.92] |
Abbreviations: UCLA; University of California Los Angeles Loneliness Scale version-3. MSS-B; Multidimensional Schizotypy-Scale Brief. CCAPS; Counseling Center Assessment of Psychological Symptoms.
Significant at p < .05.
Intercorrelations, multicollinearity statistics and internal consistency for all scales.
| Multicollinearity (Tolerance, VIF) | Internal consistency (α) | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|---|
| 1. Positive schizotypy | 0.65 (1.55) | 0.79 | 1 | ||||
| 2. Negative schizotypy | 0.71 (1.42) | 0.74 | 0.42 | 1 | |||
| 3. Disorganised schizotypy | 0.41 (2.17) | 0.89 | 0.58 | 0.51 | 1 | ||
| 4. UCLA loneliness | – | 0.90 | 0.23 | 0.44 | 0.44 | 1 | |
| 5. CCAPS depression | 0.63 (1.59) | 0.85 | 0.36 | 0.40 | 0.60⁎ | 0.72 | 1 |
Abbreviations: UCLA: University of California Los Angeles; MSS-B: multidimensional schizotypy-scale brief; CCAPS: Counseling Center Assessment of Psychological Symptoms.
Significant at p < .001.
Fig. 1Relationship between scores on the University of California (UCLA) loneliness scale and 1) positive, 2) disorganised, 3) negative schizotypy (MSS-B) and 4) depression (CCAPS).
Regression of schizotypy on loneliness by cohort.
| Dependent variable: UCLA Loneliness | Pre-COVID cohort | During COVID cohort | ||
|---|---|---|---|---|
| Predictor variable | p | p | ||
| MSS-B | ||||
| Positive schizotypy | 0.20 (0.08–0.32) | 0.002 | 0.25 (0.12–0.37) | <0.001 |
| Negative schizotypy | 0.39 (0.28–0.51) | <0.001 | 0.47 (0.36–0.58) | <0.001 |
| Disorganised schizotypy | 0.44 (0.33–0.55) | <0.001 | 0.43 (0.32–0.54) | <0.001 |
| CCAPS depression | 0.76 (0.66–0.83) | <0.001 | 0.68 (0.59–0.77) | <0.001 |
Abbreviations: MSS-B: multidimensional schizotypy-scale brief; CCAPS: Counseling Center Assessment of Psychological Symptoms.
Fig. 2Linear regression of schizotypy and depression on University of California (UCLA) loneliness scores for the pre-COVID-19 (blue) and during COVID-19 cohort (red) with 95% confidence intervals. (1) Multidimensional Schizotypy Scale-Brief (MSS-B) positive schizotypy, (2) MSS-B negative schizotypy, (3) MSS-B disorganised schizotypy, and (4) Counseling Center Assessment of Psychological Symptoms (CCAPS) depression. Overlap of confidence intervals is represented by the shaded middle area.