Literature DB >> 35212730

Improving delirium screening and recognition in UK hospitals: results of a multi-centre quality improvement project.

.   

Abstract

BACKGROUND: delirium is an acute severe neuropsychiatric condition associated with adverse outcomes, particularly in older adults. However, it is frequently under-recognised.
METHODS: this multi-centre quality improvement project utilised a collaborative approach to implementation of changes at sites, with the aim to improve delirium screening, recognition and documentation on discharge summaries. Resources, including delirium guidelines and presentations, were shared between sites, and broad details of local interventions were collected. Three timepoints of data collection (14 March 2018, 14 September 2018 and 13 March 2019) were conducted to assess screening, recognition and documentation of delirium in unscheduled admissions of adults aged ≥65 years old. The impact of local interventions and site-specific factors was assessed using logistic regression analysis, adjusting for patient factors.
RESULTS: a total of 3,013 patients (mean age 80.2, 53.8% females) were recruited across the three timepoints. Screening for delirium was associated with increased odds of recognition (aOR 4.75, CI 2.98-7.56; P < 0.001); this was not affected by grade/profession of screener. Rates of screening, recognition and discharge documentation improved across the three timepoints of data collection. The presence of a local delirium specialist team was associated with increased rates of screening for delirium (aOR 1.75, CI 1.41-2.18; P < 0.001), and the presence of a geriatric medicine team embedded into the admissions unit was associated with increased recognition rates (aOR 1.78, CI 1.09-2.92; P = 0.022).
CONCLUSION: delirium screening is associated with improved recognition. Interventions that strive to improve screening within a culture of delirium awareness are encouraged.
© The Author(s) 2022. Published by Oxford University Press on behalf of the British Geriatrics Society.

Entities:  

Keywords:  collaborative; delirium; education; older people; quality improvement

Mesh:

Year:  2022        PMID: 35212730      PMCID: PMC8876302          DOI: 10.1093/ageing/afab243

Source DB:  PubMed          Journal:  Age Ageing        ISSN: 0002-0729            Impact factor:   10.668


A multi-centre ‘crowdsourcing’ approach to quality improvement is feasible. Delirium screening, recognition and discharge documentation improved across each round of data collection. Screening for delirium increases the odds of recognition, and drives to improve screening are recommended.

Background

Delirium is an acute neuropsychiatric state defined by cognitive change and altered consciousness that occurs secondary to physical precipitants, particularly in older adults during hospitalisation [1]. Delirium is associated with adverse outcomes, but is frequently under-recognised [2]. Our previous research demonstrated that delirium screening increases recognition [1]. However, delirium screening was inconsistent. Screening and recognition were particularly reduced in surgical specialties [1]. Although delirium is reversible, it is associated with increased risk of later life dementia diagnosis [3]. Follow-up of patients who have experienced delirium is, therefore, vital. Unfortunately, delirium documentation on discharge summaries is infrequently performed [4]. In the UK, National Institute for Health and Care Excellence guidelines recommend that all adults aged ≥65 years old are screened for delirium on admission to hospital [5], and that delirium diagnoses are communicated to General Practitioners (GPs) on hospital discharge [6]. To improve screening and recognition of delirium in older adults admitted to acute care hospitals as unscheduled admissions. To improve documentation of delirium diagnoses on discharge summaries.

Methods

This study presents results of a multi-centre quality improvement project, utilising a collaborative approach. Resources and knowledge were shared between sites, and sites were able to implement interventions locally according to service needs. Three timepoints of data collection were utilised (14 March 2018, 14 September 2018 and 13 March 2019). All timepoints of data collection included newly admitted (unscheduled) patients aged ≥65 years old to acute care trusts (all specialties, excluding critical care). We assessed for statistical significance of differences in likelihood of screening, recognition and discharge documentation across timepoints using multivariable logistic regression analysis. Full methodology is Supplementary data (Figure S1, Figure S2) are available in Age and Ageing online.

Results

Timepoint 1 included 1,507 patients from 44 sites, Timepoint 2 included 656 patients from 26 sites and Timepoint 3 included 850 patients from 48 sites. Eighty-two sites contributed data to at least one timepoint (Table S1, Supplementary data are available in Age and Ageing online). Overall prevalence of delirium across all timepoints was 16.3% (491/2,522). Characteristics of patients at each timepoint are shown in Table 1. Interventions implemented at sites between timepoints are shown in Table S2, Supplementary data (Figure S1, Figure S2) are available in Age and Ageing online.
Table 1

Characteristics of study population across all timepoints

Timepoint 1Timepoint 2Timepoint 3
Delirium (N = 222)No delirium (N = 1,285)Delirium (N = 133)No delirium (N = 523)Delirium (N = 136)No delirium (N = 714)
Age—mean (SD)84.0 (7.4)79.3 (8.3)82.8 (8.1)79.6 (8.2)83.3 (7.9)80.0 (8.5)
Gender—% females (N)60.8 (135)51.6 (663)50.4 (67)55.3 (289)60.3 (82)53.8 (384)
Dementia—% (N)35.1 (78)12.9 (166)41.4 (55)14.0 (73)54.4 (74)16.2 (116)
Clinical Frailty Scale10.5 (1)4.3 (55)1.5 (2)4.1 (21)05.4 (39)
22.7 (6)11.3 (145)1.5 (2)10.9 (57)2.2 (3)9.7 (69)
33.6 (8)19.7 (253)6.8 (9)21.0 (110)2.2 (3)17.8 (127)
410.8 (24)18.1 (232)15.0 (20)19.5 (102)8.1 (11)16.0 (114)
521.2 (47)15.9 (204)10.5 (14)15.1 (79)19.1 (26)17.9 (128)
628.4 (63)17.6 (226)30.8 (41)15.9 (83)29.4 (40)17.4 (124)
725.7 (57)9.3 (119)26.3 (35)10.5 (55)32.4 (44)9.7 (69)
84.5 (10)0.9 (12)6.0 (8)1.5 (8)5.1 (7)1.3 (9)
90 (0)0.2 (3)1.5 (2)1.3 (7)0 (0)0.6 (4)
SpecialtyAcute medicine47.7 (106)42.2 (542)21.8 (29)21.2 (111)27.2 (37)18.5 (132)
Geriatric medicine26.6 (59)16.0 (206)45.1 (60)20.3 (106)37.5 (51)18.8 (134)
Stroke1.8 (4)4.0 (52)0.8 (1)5.0 (26)1.5 (2)3.9 (28)
Other medicine14.0 (31)22.1 (284)21.1 (28)27.9 (146)19.1 (26)35.9 (256)
Orthopaedic surgery6.8 (15)6.2 (80)6.0 (8)9.0 (47)8.1 (11)9.0 (64)
General surgery3.2 (7)6.5 (83)4.5 (6)8.0 (42)4.4 (6)9.1 (65)
Other surgery1.8 (4)3.0 (38)0.8 (1)8.6 (45)2.2 (3)4.3 (31)
Characteristics of study population across all timepoints

Delirium screening

Delirium screening increased across timepoints (27.3% versus 29.6% versus 37.1%; P < 0.001). Odds of screening increased between Timepoints 1 and 3 (aOR 1.33, CI 1.08–1.65; P = 0.001; Table 2). Delirium screening was associated with increasing age, mild–moderate (but not severe) frailty and dementia. Odds of delirium screening were increased with presence of specialist delirium teams (aOR 1.75, CI 1.41–2.18; P < 0.001; Table S3, Supplementary data are available in Age and Ageing online).
Table 2

Logistic regression analysis for odds of screening, recognition and discharge documentation between timepoints

Timepoint 2 versus Timepoint 1 Timepoint 3 versus Timepoint 1
OR (CI) P value OR (CI) P value
Delirium screening
 Unadjusted1.18 (0.95–1.46)0.1421.45 (1.18–1.78)<0.001
 Adjusted¥1.07 (0.85–1.34)0.5701.33 (1.08–1.65)0.001
Delirium recognition
 Unadjusted2.60 (1.62–4.16)<0.0012.31 (1.41–3.77)0.001
 Adjustedǂ1.93 (1.11–3.35)0.0192.33 (1.31–4.15)0.004
Discharge documentation
 Unadjusted2.34 (1.23–4.46)0.0091.78 (1.02–3.11)0.042
 Adjusted¥2.27 (1.10–4.68)0.0261.73 (0.93–3.24)0.085

¥Adjusted for Clinical Frailty Scale, age, gender, dementia status, specialty and site-specific factors.

ǂAdjusted for screening, subtype, Clinical Frailty Scale, age, gender, dementia status, specialty and site-specific factors.

Logistic regression analysis for odds of screening, recognition and discharge documentation between timepoints ¥Adjusted for Clinical Frailty Scale, age, gender, dementia status, specialty and site-specific factors. ǂAdjusted for screening, subtype, Clinical Frailty Scale, age, gender, dementia status, specialty and site-specific factors.

Delirium recognition

Delirium recognition increased across timepoints (34.2% versus 57.1% versus 63.2%; P < 0.001). Odds of recognition increased between Timepoints 1 and 2 (aOR 1.93, CI 1.11–3.35; P = 0.019), and 1 and 3 (aOR 2.33, CI 1.31–4.15; P = 0.004; Table 2). Screening for delirium was associated with delirium recognition (aOR 4.75, CI 2.98–7.56; P < 0.001); this was not affected by grade/profession of screener. Recognition odds were increased in patients with dementia (aOR 1.73, CI 1.06–2.84; P = 0.029), and presence of geriatric teams embedded into admissions units (aOR 1.78, CI 1.09–2.92; P = 0.022). Admissions under general (aOR 0.11, CI 0.02–0.58; P = 0.009) or orthopaedic (aOR 0.27, CI 0.09–0.79; P = 0.017) surgery were associated with reduced delirium recognition (Table S4, Supplementary data are available in Age and Ageing online).

Discharge documentation

Discharge documentation increased across timepoints (28.6% versus 48.4% versus 46.6%; P = 0.002) (Table 2). Odds of discharge documentation increased from Timepoint 1 to 2 (aOR 2.34, CI 1.23–4.46; P = 0.009). Odds of delirium documentation were increased in patients with dementia (aOR 2.01, CI 1.16–3.48; P = 0.012), but not affected by site-specific factors (Table S5, Supplementary data are available in Age and Ageing online).

Discussion

Delirium screening, recognition and discharge documentation all improved overall, demonstrating that rates of these are not fixed/inalterable. Importantly, screening is associated with increased odds of recognition; efforts to increase screening should be encouraged. Notably, grade and profession of screener did not affect recognition. Therefore, interventions to improve recognition may utilise trained multiprofessional screeners and junior staff. The 4AT has been validated for use by all healthcare professionals with minimal training [7, 8]. Discharge documentation was more likely in patients with pre-existing dementia. Reasons for this are unclear, but may relate to greater awareness of importance of delirium in dementia, in a similar manner to increased recognition rates. There may be a general misunderstanding as to why communication of delirium diagnoses to GPs is important, in terms of highlighting risk of future cognitive decline [3, 9]. Encouragingly, documentation improved across timepoints. Previous studies have shown that discharge documentation is often inadequate across many settings [10].

External validity

Overall delirium prevalence was 16.3%. This is lower than a previous single-site point prevalence study (19.6%) [11]. Differences are accounted for by inclusion of incident delirium in the latter study; only prevalent cases at admission were included at Timepoints 1 and 3. A higher prevalence rate (22.9%) was reported in a study considering positive screen with 4AT alone and not reference-standard delirium diagnosis [12]. Previous single centre quality improvement projects have demonstrated similar improvements in delirium screening and recognition with local interventions. A previous study involving implementation of a local delirium pathway and multidisciplinary teaching programme demonstrated improvement in delirium recognition rates from 5.7 to 35% over 11 weeks [13]. Similarly, implementation of dedicated teaching sessions within an acute medical unit, and management bundle with checklists, resulted in improved delirium screening rates from 40 to 61% [14].

Internal validity

Patient characteristics were similar across timepoints with regards to age, gender and specialties. Most patients were within acute and geriatric medicine specialties, which is consistent with recognised pathways of care within the UK [15]. However, at later timepoints higher dementia rates were recorded. Our results demonstrated that delirium was more likely to be recognised in patients with dementia. However, effects persisted in multivariable models adjusting for dementia. We recognise that a significant limitation is that not all the same sites participated at each timepoint. Analyses and interpretation were performed for sites overall rather than at site level; site level analysis was not possible due to individually small numbers. Nevertheless, improvement in screening, recognition and documentation across timepoints demonstrates that such improvements are possible. We acknowledge that methodology differed between timepoints; data was collected prospectively at Timepoints 1 and 3 but retrospectively at Timepoint 2. We consider this variation unlikely to have significantly impacted upon results. Validated methodology for retrospective delirium ascertainment was used at Timepoint 2 [16, 17]. In addition, although this may have led to differences in recognition rates, this should not have affected screening rates. Documentation of screening was extracted from clinical records across all timepoints. We cannot be certain specific interventions led to improvements, or if these relate to external factors. It is conceivable that improvements across timepoints related to improved culture of embedding delirium screening and assessment into clinical practice. This may have occurred due to leadership of collaborators at sites. However, many doctors rotated sites during this project, and collaborators at sites differed between timepoints. This suggests that changes can be sustained, even where leadership is rotated. Improved delirium screening and recognition rates may also be related to external factors. The International Federation of Delirium Studies (iDelirium) is an international collaboration of societies, which seeks to educate patients, caregivers, professionals and policy makers about delirium [18]. The society constantly aims to increase awareness of delirium, however, national campaigns peek around the time of WDAD (i.e. first and last timepoints) [18].

Recommendations

Our approach of sharing guidelines, resources and a central data collection point is feasible in involving multiple centres across multiple timepoints. Methodology was sufficiently simple to enable healthcare professionals of any grade or profession to be involved with screening and data collection. This is a model that may be replicated in future collaborative quality improvement projects. Despite the focus on screening and recognition, it is important to recognise that assessment is only part of management. If delirium is present and recognised this should prompt healthcare professionals to take action by identifying and treating underlying causes [19]. Education should focus on rationale behind actions, such as the need to ensure delirium is communicated to primary care to enable appropriate follow-up of cognitive trajectories. Delirium may take some time to fully resolve [20], and communication to primary care is of utmost importance. Although it was not possible to analyse site level data for effectiveness of individual interventions at site, we were able to identify site factors that were predictive of screening and recognition. Specialist delirium teams were associated with improved screening rates, and geriatric medicine teams embedded into admissions units were associated with improved recognition rates. Where sites are seeking to improve screening and recognition rates locally, we suggest that these findings are considered in service development. There was a very strong association (nearly fivefold) between delirium screening and likelihood of delirium recognition. Thus, drivers towards increased delirium screening are likely to prove beneficial.

Conclusions

A collaborative approach to multi-centre quality improvement is feasible; including multiple data collection timepoints, and sharing of guidelines/resources and knowledge across sites. Importantly, screening, recognition and delirium documentation rates are not fixed/unalterable; improved rates across timepoints suggest potential for responsiveness to interventions. Screening for delirium is associated with increased likelihood of delirium recognition. We encourage implementation of interventions to improve recognition through way of increased screening, alongside sustainable culture changes. Click here for additional data file.

Members of the Geriatric Medicine Research Collaborative

Manuscript preparation
First name Middle initial Last name Affiliation
JulianLinTorbay and South Devon NHS Foundation Trust
SindhooraDamaSouth Warwickshire Foundation Trust
CarlyWelchUniversity of Birmingham
Steering group
ThomasA.JacksonUniversity of Birmingham
LauraMagill
LaurenMcCluskey
RitaPerry
DaisyWilson
Advisory group
ClaireCopelandNHS Forth Valley
EmmaCunninghamQueen’s University Belfast
DanielDavisUniversity College London
JonathanTremlUniversity Hospitals Birmingham NHS Foundation Trust
ThomasPinkneyUniversity of Birmingham
TerrenceQuinnUniversity of Glasgow
Data analysis advisor
PeterNightingaleUniversity Hospitals Birmingham NHS Foundation Trust
Regional leads
BenjaminJelleyCardiff and Vale University Health Board
VictoriaGauntGloucestershire Hospitals NHS Foundation Trust
MaryNi LochlainnKing’s College London
KumudhiniGiridharanMaidstone & Tunbridge Wells NHS Trust
SarahRichardsonNewcastle University
MustafaAlsahabOxford University Hospitals NHS Foundation Trust
StephenMakinUniversity of Aberdeen
KelliTorsneyUniversity of Cambridge
JaneMasoliUniversity of Exeter
LindsayRonanUniversity of Exeter
JenniK.BurtonUniversity of Glasgow
OliverToddUniversity of Leeds
JoanneTaylorUniversity of Manchester
RuthWillottUniversity of Nottingham
NatalieCoxUniversity of Southampton
RoisinHealyWestern Health and Social Care Trust
Other collaborators
NedaaHaddadAnuerin Bevan University Health Board
SharanRamakrishna
ZahidSubhan
AntonellaMazzoleniBarnet, Enfield and Haringey Mental Health Liaison Service
OlgaNynaes
JodieCroftsBarnsley District General Hospital
EmilyMcNicholas
HannahJ.Robinson
ThynThyn
JonathanBaillieBelfast Health and Social Care Trust
WilliamMcKeown
CarolineRice
GerrardW.Sloan
KatherineWilliamson
YasmeenHayatBolton NHS Foundation Trust
Vee HanLim
KatieMillichamp
AmrBazaraaBradford Teaching Hospitals NHS Foundation Trust
AngharadChilton
AlexanderHarbinson
JohnHeadlam
ElisabethHunter
ZainabHussain
Al WakkassMahmood
LijiNg
SrividyaSundara
FeliciaTan
AliceWheeler
SophieWright
JackB.G.BaldwinBrighton and Sussex University Hospitals NHS Trust
KateO'shea
GhazalHodhodyBuckinghamshire Healthcare NHS Trust
KaraMayor
RianaPatel
ShivBhaktaCambridge University Hospitals
MarieGoujon
AdrianaJakupaj
JamesDoveCamden & Islington NHS Foundation Trust
MatthewKearneyCounty Durham and Darlington NHS Foundation Trust
VincentMcCormack
KirstyMoore
LeoPope
Hussun-AraShah
MeganE.Shaw
GemmaM.Smith
RyanLoveEast and North Hertfordshire NHS Trust
MayaMukundan
MuhammadShahid
AhmadAlareed
ClementineAnderson
KarenBeharry
GanapathyBhat
SanojanBremakumar
LaurenceCaines
SandraDarko
NishaRai
DavidSaliu
PedroVila De Mucha
PhillipaAdamsGateshead Health NHS Foundation Trust
HelenMcDonaldGloucestershire Hospitals NHS Foundation Trust
SamMills
FrancesParry
FrancesRickard
StuartWinearls
RinataFarahGreat Western Hospitals NHS Trust
RobertGrange
FionaHerbert
ElizabethLonsdale-Eccles
QurratUl Ain
HannahWatson
CelineBultynckGuy’s & St Thomas’ NHS Foundation Trust
ChiaraCavaliere
CalDoherty
SarahEvans
DanielFurmedge
AnnabelHentall MacCuish
EstherHindley
CaitlinMeyer
EmmaMullarkey
RosamundPullen
AidanRyan
DhruvSarma
ElaineSeymour
KatharineStambollouian
DarmigaThayabaran
ChenxianWu
GeorgePeckImperial College London Healthcare Trust
MahrukhRaza
KapilSahnan
AmberDhillonKeele University
OluwatosinO.AbiolaKing's College Hospital NHS Foundation Trust
CatherineBryant
RachaelBygate
JohnFrewen
IsabelGreaves
OliviaMorrow
SimonTetlow
GuyTinson
AayenahYunus
SimranBediKing's College London
OliviaEvansLewisham & Greenwich NHS Trust
LeeyingGiet
TaranNandra
AbolfazlBehbahaniLiverpool University
SauravBhattacharyaMaidstone and Tunbridge Wells NHS Trust
ClareHunt
RajeevMishra
LouiseConnorNewcastle University
JackPoynton
ElizabethDeaconNewcastle Upon Tyne Hospitals NHS Foundation Trust
RoryDurcan
EmmaFisken
SusanA.Hall
JaneNoble
EmmaL.Prendergast
AjayMacharouthuNHS Ayrshire and Arran
VictoriaMacrae
EmilyMurphy-Ackroyd
EmilyC.Rose
NicolaWatt
MairiBlairNHS Forth Valley
EilidhR.Mackenzie
RoisinMcCormack
SophieJ.IrwinNHS Gateshead
AliceEinarssonNHS Grampian
MingKhor
BaraaAlhadadiNHS Greater Glasgow and Clyde
EwenCameron
AngelaCampbell
EileenCapek
LornaChristie
LauraConnell
AlanCook
JordannaDeosaran
MarianneElliott
ElizabethEvans
SarahFancourt
SarahHenderson
AmbreenHussain
KarenJones
DominicKelly
CatherineMaryMcErlean
HazelMiller
FarihaNaeem
CarolineOstrowski
MeganParkinson
FadiSami
AlisonShepherd
LindsayWhyte
EmilyWright
EilidhE.C.FergusonNHS Lanarkshire
MichaelGallagher
HeatherJ.McCluskey
LouiseBeveridgeNHS Tayside
HollieA.Clements
JasmineHart
NeilHenderson
Su KwanLim
JamesE.Lucocq
AlisonMcCulloch
AdamA.Murray
EstherE.Y.Ngan
PhilippaK.Traill
AmyWalter
MichaelS.J.Wilson
AbigailWrathall
Zhi JiunYap
HashemAbu-ArafehNorth Middlesex University Hospital NHS Trust
IlanGluck
OliverMitchell
RichardRobson
ElizabethL.Sampson
ArunkumarAnnamalaiNorth Tees and Hartlepool NHS Foundation Trust
JamalBhatti
LauraBriggs
DebbieFraser
JonathanGui
EleanorLeah
NatashaMatthews
PryankaranMithrakumar
MohammadMoad
MichaelSen
JacquiStraughan
RoxanaTaranu
KasimUsmani
AyeshaAamirNorth West Anglia NHS Foundation Trust
AmakaAchara
OlugbenroAkintade
ElizabethJ.Ellis
SnehaGurung
ChiomaIwu
AbdullahB.Khalid
SejloKoshedo
ShonitNagumantry
NaderNashed
PhilipNwabufor
IjeomaT.Obi
ParrthiepanVisvaratnam
EdwardWu
MarcBertagneNorthern Devon Healthcare NHS Trust
PeterJackson
JamesAllenOxford University Hospitals NHS Foundation Trust
HarrietBrown
JenniferChampion
NatashaChristodoulides
OliviaHandleyPoole Hospital NHS Foundation Trust
FionaE.Macdonald
LauraJ.BeeleyRoyal Cornwall Hospitals NHS Trust
VictoriaClayton
AaronKay
JohnMarshall
HannahMorgan
GeorgeNaish
SarahL.CleaverRoyal Devon & Exeter Hospital NHS Foundation Trust
JennyEvans
AbbieMorrow
RajAmarnaniRoyal Free London NHS Foundation Trust
KhaiL.Cheah
ClaireCushen
AmyEnfield-Bance
MartinGlasser
SuritiGovindji
ShamaMani
JemmaGregorySandwell and West Birmingham NHS Trust
PujaJatti
AsmaKhan
HelenaLee
HelenMillner
HumaNaqvi
EmilyWilliamson
TeresaHarkinSherwood Forest Hospitals NHS Foundation Trust
BushraKhizar
AnnaLewis
HannahPendleton
SteveRutter
RohanAhmedShrewsbury and Telford Hospital Trust
FarahCoffey
WaleedFaheem
BethHackett
ElizabethA.M.Holmes
AliKhan
ZeeshanMustafa
MarkA.BowmanSouth Eastern Health and Social Care Trust
JamesIrvine
KatherinePatterson
SarahHornerSouth Tees Hospitals NHS Foundation Trust
TingW.Wong
ChristopherCairnsSouth Tyneside and Sunderland NHS Foundation Trust
KateFoster
AlexHornsby
RobbieHorton
LauraJones
RachelKing
EmilyLyon
AniTencheva
FayeWilson
LesleyJ.Young
EleanorGiblinSouth Warwickshire Foundation Trust
LleikaKunaselan
OliviaLowes
ReemaMenezes
AbigailTaylor
AlexTimperley
RachelBatho
CharlotteBell
SammyCarter
PaulCroft
ElizaGriffiths
GilesHall
WilliamHunt
HollyJacques
FelicityLeishman
SeemaMurthy
SineadQuinn
JamesReid
AmyWalker
StephanieA.MatthewsSouthend University Hospital Trust
AyoubBehbahaniSouthport and Ormskirk Hospital NHS Trust
MartinGlasserSt George's University Hospital NHS Trust
AnaSilva FerreiraSurrey and Sussex Healthcare NHS Trust
CarolineAshtonThe Princess Alexandra Hospital NHS Trust
SwethaByravanThe Royal Wolverhampton NHS Trust
LauraCummings
SanaFaruq
SarahJagdeo
PhilipThomas
KarenBroadhurstTorbay and South Devon NHS Foundation Trust
JosephB.Wilson
HelenBowdenUniversity College London
KatrinHoffman
HowellT.Jones
CharlesKatz-Summercorn
EthanKhambay
LucyPorter
JamesSpeed
KeziahAustinUniversity College London Hospitals NHS Foundation Trust
FarrahBahsoon
RoseLaud
JawadAliUniversity Hospitals Birmingham NHS Trust (Birmingham Heartlands Hospital)
NiallFergusson
ClaireWilkes
LauraBabbUniversity Hospitals Birmingham NHS Trust (Good Hope Hospital) University Hospitals Birmingham NHS Trust (Good Hope Hospital)
JamesGaywood
JessicaGreen
AdaKantczak
KatyF.Madden
SashaPorter-Bent
MoeSu Su San
LaxmiBabarUniversity Hospitals Birmingham NHS Trust (Queen Elizabeth Hospital Birmingham)
HelenChamberlain
TamsinCricklow
AlexisGiles
AbhishekGupta
ClareHughes
TammyLee
AnumCheemaUniversity Hospitals Birmingham NHS Trust (Solihull Hospital)
YathuMatheswaran
AsioduNneamaka
AnekeaRoss
TarunyaVedutla
TheresaJ.AllainUniversity Hospitals Bristol NHS Trust
EmilyBowen
JulieDovey
NatalieGaskell
DeborahScott
EmmaStratton
MiriamThake
StuartBullockUniversity Hospitals Coventry and Warwickshire NHS Trust
SiobhanMcKay
StephanieRadoja
SherifAbdelbadieeUniversity Hospitals of Leicester NHS Trust
SamuelCohen
JaneGiddings
ChristopherJ.Miller
EmmaMumtaz
MinalD.Patel
VishnuPrasad
LahiruSatharasinghe
MarkStudley
MarylinBrowneUniversity Hospitals of North Midlands NHS Trust
SabrinaK.Durrant
EmmaJay
AlexMcQuillan
MeganOffer
JesselVarghese
AlexanderBaronUniversity Hospitals Plymouth NHS Trust
ChristianChourot
PeterJackson
KimberleyKirrane
HelenRayner
KateTantam
EbrahiemTumi
ShabnamVenkat
NishaAggarwalUniversity of Birmingham
EmmaAstaire
KarthikBasker
LBerwick
EdwardBilton
Aimee-LouiseChamboult
GeorgeChapman
JasmineChevolleau
GraceFenneley
ShannelleHouse
NathanIngamells
EmiliaJewell
VickneswaranKalyaani
MahumKiani
NagarjunKonda
AnushaKumar
JoLai
JamieLarge
JoannaLivesey
ZeinabMajid
JackMcCready
HannahMoorey
BethanMorgan
KirtyMorrison
AliceMosley
AdamPailing
SophiePettler
ShayanRashid
LucyRimmer
DanielleScarlett
GurpreetSehmi
AbigailSmith
NinaSmith
CharlesSprosen
EmilyTaylor
JemimaTaylor
ConnieTse
SophieTurton
HenryVardon
JasmineVirk
SarahWarwicker
HannahWoodman
BethL.Woodward
LukeWynne
LeahYule
AsimAhmadUniversity of Bristol
PaapaAppiah-Odame
CiaranBarlow
DorothyKuek
IsabelleNicholls
EmmaNorman
WiolettaPyc
AshishVasudev
LawrenceA.T.AdamsUniversity of Dundee
EmmaBox
Chung SienChai
DarcyS.Wilson
BognaDrozdowskaUniversity of Glasgow
EmmaElliott
AdamStirling
MartinTaylor-Rowan
HannahWebb
LiWong
AhmedAbrasWalsall Healthcare NHS Trust
MuhammadAdam
ZarahAmin
OliviaCooper
RhiannaDavies
Wan IdoracaeraC.Ikhwan
GeorgiaR.Layton
AwolkhierMohammedseid-Nurhussien
SohailShakeel
HanaWaraich
JabedAhmedWest Hertfordshire Hospitals NHS Trust
KatieBall
KwasiDebrah
ValeriePage
ZhaoXiao Bei
HannahMcCauleyWestern Health and Social Care Trust
DavidMcShane
FreyaCooperWeston Area Health NHS Trust
NatalieGrundmann
MichaelHaley
AndreLe Poideven
SarahB.McClelland
EmilyMoore
NormanPang
HannahCurrieWye Valley NHS Trust
JayneDavies-Morris
SarahEdwards
SureenaJanagal
RodricJenkin
PollyJones
GaryKumbun
SarahParry
BhavTyagi
JanineValentineYeovil District Hospital NHS Foundation Trust
SaadAbdullahYork Teaching Hospital NHS Foundation Trust
EmmyAbu
SarahAhmad
BilquisAhmed
HamzaAhmed
AnaAndrusca
MatthewAnsell
ThomasArkle
ImolaBargaoanu
CharlotteChuter
KatieHouldershaw
JacquelineIbanichuka
ShoaibIqbal
AngelaKabia
IsmailKadir
AnjliKrishan
AdamMcClean
GerryMcGonigal
PranavMishra
GladysOfoche
AnnaReay
SimonM.Stapley
AdamSwietoslawski
NihaadSyed
KarthikaVelusamy
AfnanWahballa
JamesWilcockson
  15 in total

Review 1.  Deficits in communication and information transfer between hospital-based and primary care physicians: implications for patient safety and continuity of care.

Authors:  Sunil Kripalani; Frank LeFevre; Christopher O Phillips; Mark V Williams; Preetha Basaviah; David W Baker
Journal:  JAMA       Date:  2007-02-28       Impact factor: 56.272

2.  Validation of a consensus method for identifying delirium from hospital records.

Authors:  Elvira Kuhn; Xinyi Du; Keith McGrath; Sarah Coveney; Niamh O'Regan; Sarah Richardson; Andrew Teodorczuk; Louise Allan; Dan Wilson; Sharon K Inouye; Alasdair M J MacLullich; David Meagher; Carol Brayne; Suzanne Timmons; Daniel Davis
Journal:  PLoS One       Date:  2014-11-04       Impact factor: 3.240

3.  Diagnostic accuracy of the 4AT for delirium detection in older adults: systematic review and meta-analysis.

Authors:  Zoë Tieges; Alasdair M J Maclullich; Atul Anand; Claire Brookes; Marica Cassarino; Margaret O'connor; Damien Ryan; Thomas Saller; Rakesh C Arora; Yue Chang; Kathryn Agarwal; George Taffet; Terence Quinn; Susan D Shenkin; Rose Galvin
Journal:  Age Ageing       Date:  2021-05-05       Impact factor: 10.668

4.  Undiagnosed long-term cognitive impairment in acutely hospitalised older medical patients with delirium: a prospective cohort study.

Authors:  Thomas A Jackson; Alasdair M J MacLullich; John R F Gladman; Janet M Lord; Bart Sheehan
Journal:  Age Ageing       Date:  2016-04-13       Impact factor: 10.668

5.  Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study.

Authors:  Daniel H J Davis; Graciela Muniz Terrera; Hannah Keage; Terhi Rahkonen; Minna Oinas; Fiona E Matthews; Colm Cunningham; Tuomo Polvikoski; Raimo Sulkava; Alasdair M J MacLullich; Carol Brayne
Journal:  Brain       Date:  2012-08-09       Impact factor: 13.501

6.  Validation of the 4AT, a new instrument for rapid delirium screening: a study in 234 hospitalised older people.

Authors:  Giuseppe Bellelli; Alessandro Morandi; Daniel H J Davis; Paolo Mazzola; Renato Turco; Simona Gentile; Tracy Ryan; Helen Cash; Fabio Guerini; Tiziana Torpilliesi; Francesco Del Santo; Marco Trabucchi; Giorgio Annoni; Alasdair M J MacLullich
Journal:  Age Ageing       Date:  2014-03-02       Impact factor: 10.668

7.  Delirium awareness - Improving recognition and management through education and use of a care pathway.

Authors:  Ruben Tauro
Journal:  BMJ Qual Improv Rep       Date:  2014-02-04

8.  Can delirium research activity impact on routine delirium recognition? A prospective cohort study.

Authors:  Carly Welch; Thomas A Jackson
Journal:  BMJ Open       Date:  2018-10-31       Impact factor: 2.692

9.  Delirium is prevalent in older hospital inpatients and associated with adverse outcomes: results of a prospective multi-centre study on World Delirium Awareness Day.

Authors: 
Journal:  BMC Med       Date:  2019-12-14       Impact factor: 8.775

10.  Retrospective delirium ascertainment from case notes: a retrospective cohort study.

Authors: 
Journal:  BMJ Open       Date:  2021-05-28       Impact factor: 2.692

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.