Literature DB >> 35210039

Inflammation, Aging, and Cardiovascular Disease: JACC Review Topic of the Week.

Luca Liberale1, Lina Badimon2, Fabrizio Montecucco3, Thomas F Lüscher4, Peter Libby5, Giovanni G Camici6.   

Abstract

Aging and inflammation both contribute pivotally to cardiovascular (CV) and cerebrovascular disease, the leading causes of death and disability worldwide. The concept of inflamm-aging recognizes that low-grade inflammatory pathways observed in the elderly contribute to CV risk. Understanding the mechanisms that link inflammation and aging could reveal new therapeutic targets and offer options to cope with the growing aging population worldwide. This review reports recent scientific advances in the pathways through which inflamm-aging mediates age-dependent decline in CV function and disease onset and considers critically the translational potential of such concepts into everyday clinical practice.
Copyright © 2022 American College of Cardiology Foundation. All rights reserved.

Entities:  

Keywords:  cardiovascular disease; inflamm-aging; inflammation; vascular aging

Mesh：

Year:  2022        PMID： 35210039      PMCID： PMC8881676          DOI： 10.1016/j.jacc.2021.12.017

Source DB:  PubMed          Journal:  J Am Coll Cardiol        ISSN： 0735-1097            Impact factor:   24.094


  74 in total

1.  Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adults.

Authors:  Ravi Varadhan; Wenliang Yao; Amy Matteini; Brock A Beamer; Qian-Li Xue; Huanle Yang; Bhavish Manwani; Alexander Reiner; Nancy Jenny; Neel Parekh; M Daniele Fallin; Anne Newman; Karen Bandeen-Roche; Russell Tracy; Luigi Ferrucci; Jeremy Walston
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2013-05-20       Impact factor: 6.053

2.  Association of Clonal Hematopoiesis of Indeterminate Potential With Inflammatory Gene Expression in Patients With Severe Degenerative Aortic Valve Stenosis or Chronic Postischemic Heart Failure.

Authors:  Wesley Tyler Abplanalp; Silvia Mas-Peiro; Sebastian Cremer; David John; Stefanie Dimmeler; Andreas M Zeiher
Journal:  JAMA Cardiol       Date:  2020-10-01       Impact factor: 14.676

3.  Gut Microbiota and Extreme Longevity.

Authors:  Elena Biagi; Claudio Franceschi; Simone Rampelli; Marco Severgnini; Rita Ostan; Silvia Turroni; Clarissa Consolandi; Sara Quercia; Maria Scurti; Daniela Monti; Miriam Capri; Patrizia Brigidi; Marco Candela
Journal:  Curr Biol       Date:  2016-05-12       Impact factor: 10.834

4.  Identification of a geographic area characterized by extreme longevity in the Sardinia island: the AKEA study.

Authors:  Michel Poulain; Giovanni Mario Pes; Claude Grasland; Ciriaco Carru; Luigi Ferrucci; Giovannella Baggio; Claudio Franceschi; Luca Deiana
Journal:  Exp Gerontol       Date:  2004-09       Impact factor: 4.032

5.  CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease.

Authors:  Soichi Sano; Kosei Oshima; Ying Wang; Yasufumi Katanasaka; Miho Sano; Kenneth Walsh
Journal:  Circ Res       Date:  2018-05-04       Impact factor: 17.367

6.  Age-associated epigenetic modifications in human DNA increase its immunogenicity.

Authors:  Anshu Agrawal; Jia Tay; Gi-Eun Yang; Sudhanshu Agrawal; Sudhir Gupta
Journal:  Aging (Albany NY)       Date:  2010-03-20       Impact factor: 5.682

7.  Clonal Hematopoiesis-Driver DNMT3A Mutations Alter Immune Cells in Heart Failure.

Authors:  Andreas M Zeiher; Stefanie Dimmeler; Wesley Tyler Abplanalp; Sebastian Cremer; David John; Jedrzej Hoffmann; Bianca Schuhmacher; Maximillian Merten; Michael A Rieger; Mariuca Vasa-Nicotera
Journal:  Circ Res       Date:  2020-11-06       Impact factor: 17.367

8.  DNA methylation-based measures of biological age: meta-analysis predicting time to death.

Authors:  Brian H Chen; Riccardo E Marioni; Elena Colicino; Marjolein J Peters; Cavin K Ward-Caviness; Pei-Chien Tsai; Nicholas S Roetker; Allan C Just; Ellen W Demerath; Weihua Guan; Jan Bressler; Myriam Fornage; Stephanie Studenski; Amy R Vandiver; Ann Zenobia Moore; Toshiko Tanaka; Douglas P Kiel; Liming Liang; Pantel Vokonas; Joel Schwartz; Kathryn L Lunetta; Joanne M Murabito; Stefania Bandinelli; Dena G Hernandez; David Melzer; Michael Nalls; Luke C Pilling; Timothy R Price; Andrew B Singleton; Christian Gieger; Rolf Holle; Anja Kretschmer; Florian Kronenberg; Sonja Kunze; Jakob Linseisen; Christine Meisinger; Wolfgang Rathmann; Melanie Waldenberger; Peter M Visscher; Sonia Shah; Naomi R Wray; Allan F McRae; Oscar H Franco; Albert Hofman; André G Uitterlinden; Devin Absher; Themistocles Assimes; Morgan E Levine; Ake T Lu; Philip S Tsao; Lifang Hou; JoAnn E Manson; Cara L Carty; Andrea Z LaCroix; Alexander P Reiner; Tim D Spector; Andrew P Feinberg; Daniel Levy; Andrea Baccarelli; Joyce van Meurs; Jordana T Bell; Annette Peters; Ian J Deary; James S Pankow; Luigi Ferrucci; Steve Horvath
Journal:  Aging (Albany NY)       Date:  2016-09-28       Impact factor: 5.682

9.  Age-related DNA methylation changes are sex-specific: a comprehensive assessment.

Authors:  Igor Yusipov; Maria Giulia Bacalini; Alena Kalyakulina; Mikhail Krivonosov; Chiara Pirazzini; Noémie Gensous; Francesco Ravaioli; Maddalena Milazzo; Cristina Giuliani; Maria Vedunova; Giovanni Fiorito; Amedeo Gagliardi; Silvia Polidoro; Paolo Garagnani; Mikhail Ivanchenko; Claudio Franceschi
Journal:  Aging (Albany NY)       Date:  2020-12-03       Impact factor: 5.682

10.  Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment.

Authors:  Ellen Quarles; Nathan Basisty; Ying Ann Chiao; Gennifer Merrihew; Haiwei Gu; Mariya T Sweetwyne; Jeanne Fredrickson; Ngoc-Han Nguyen; Maria Razumova; Kristina Kooiker; Farid Moussavi-Harami; Michael Regnier; Christopher Quarles; Michael MacCoss; Peter S Rabinovitch
Journal:  Aging Cell       Date:  2019-12-10       Impact factor: 9.304
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  6 in total

1.  Editorial: Targeting Dysregulated Inflammation to Treat Cardiovascular Diseases.

Authors:  Mabel Buelna-Chontal; Shyam S Bansal; Jonatan Barrera-Chimal; Luca Liberale
Journal:  Front Cell Dev Biol       Date:  2022-05-16

Review 2.  Pulse Wave Velocity and Sarcopenia in Older Persons-A Systematic Review and Meta-Analysis.

Authors:  Karolina Piotrowicz; Alicja Klich-Rączka; Anna Skalska; Barbara Gryglewska; Tomasz Grodzicki; Jerzy Gąsowski
Journal:  Int J Environ Res Public Health       Date:  2022-05-26       Impact factor: 4.614

Review 3.  Modern Concepts in Cardiovascular Disease: Inflamm-Aging.

Authors:  Yustina M Puspitasari; Stefano Ministrini; Lena Schwarz; Caroline Karch; Luca Liberale; Giovanni G Camici
Journal:  Front Cell Dev Biol       Date:  2022-05-18

4.  Novel biomarkers of inflammation in heart failure with preserved ejection fraction: analysis from a large prospective cohort study.

Authors:  Nicholas W Carris; Rahul Mhaskar; Emily Coughlin; Easton Bracey; Srinivas M Tipparaju; Ganesh V Halade
Journal:  BMC Cardiovasc Disord       Date:  2022-05-14       Impact factor: 2.174

Review 5.  Role of Inflammation in Cardiac Remodeling After Acute Myocardial Infarction.

Authors:  Francisco A Fonseca; Maria C Izar
Journal:  Front Physiol       Date:  2022-06-28       Impact factor: 4.755

Review 6.  Role of the CCL2-CCR2 axis in cardiovascular disease: Pathogenesis and clinical implications.

Authors:  Haixia Zhang; Ke Yang; Feng Chen; Qianqian Liu; Jingyu Ni; Weilong Cao; Yunqing Hua; Feng He; Zhihao Liu; Lan Li; Guanwei Fan
Journal:  Front Immunol       Date:  2022-08-30       Impact factor: 8.786
  6 in total

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