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Literature DB >> 3519586

Genetic complementation in Cryptococcus neoformans.

Abstract

A complementation test was devised for the fungus Cryptococcus neoformans. Complementation was signalled by the growth of prototrophic heterokaryons generated in crosses of the type aB X Ab, where a and b represent any two of the genetic markers ilv1, cys1, cys2, and cys3. The cloned complementing heterokaryons formed characteristic hyphal colonies that contained both hyphae and yeast cells. The heterokaryon-derived yeasts were of three kinds: parental haploids, recombinant haploids, and diploids.

Entities: Chemical Species

Mesh：

Year: 1986 PMID： 3519586 PMCID： PMC215214 DOI： 10.1128/jb.166.3.924-929.1986

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

5 in total

1. A new genus, filobasidiella, the perfect state of Cryptococcus neoformans.

Authors: K J Kwon-Chung
Journal: Mycologia Date: 1975 Nov-Dec Impact factor: 2.696

2. Occurrence of diploid strains of Cryptococcus neoformans.

Authors: C W White; E S Jacobson
Journal: J Bacteriol Date: 1985-03 Impact factor: 3.490

3. Recombinational mapping of capsule mutations in Cryptococcus neoformans.

Authors: C N Still; E S Jacobson
Journal: J Bacteriol Date: 1983-10 Impact factor: 3.490

4. Morphogenesis of Filobasidiella neoformans, the sexual state of Cryptococcus neoformans.

Authors: K J Kwon-Chung
Journal: Mycologia Date: 1976 Jul-Aug Impact factor: 2.696

5. Nuclear genotypes of spore chains in Filobasidiella neoformans (Cryptococcus neoformans).

Authors: K J Kwon-Chung
Journal: Mycologia Date: 1980 Mar-Apr Impact factor: 2.696

5 in total

7 in total

1. Calcineurin is required for virulence of Cryptococcus neoformans.

Authors: A Odom; S Muir; E Lim; D L Toffaletti; J Perfect; J Heitman
Journal: EMBO J Date: 1997-05-15 Impact factor: 11.598

2. Cloning of 18S and 25S rDNAs from the pathogenic fungus Cryptococcus neoformans.

Authors: B I Restrepo; A G Barbour
Journal: J Bacteriol Date: 1989-10 Impact factor: 3.490

3. Serotype AD strains of Cryptococcus neoformans are diploid or aneuploid and are heterozygous at the mating-type locus.

Authors: K B Lengeler; G M Cox; J Heitman
Journal: Infect Immun Date: 2001-01 Impact factor: 3.441

Genetic complementation in Cryptococcus neoformans.

1. A new genus, filobasidiella, the perfect state of Cryptococcus neoformans.

2. Occurrence of diploid strains of Cryptococcus neoformans.

3. Recombinational mapping of capsule mutations in Cryptococcus neoformans.

4. Morphogenesis of Filobasidiella neoformans, the sexual state of Cryptococcus neoformans.

5. Nuclear genotypes of spore chains in Filobasidiella neoformans (Cryptococcus neoformans).

1. Calcineurin is required for virulence of Cryptococcus neoformans.

2. Cloning of 18S and 25S rDNAs from the pathogenic fungus Cryptococcus neoformans.

3. Serotype AD strains of Cryptococcus neoformans are diploid or aneuploid and are heterozygous at the mating-type locus.

4. Unraveling the biology of a fungal meningitis pathogen using chemical genetics.

5. Separation of chromosomes of Cryptococcus neoformans by pulsed field gel electrophoresis.

6. Genetic Diversity and Genomic Plasticity of Cryptococcus neoformans AD Hybrid Strains.

7. Cryptococcus neoformans STE12alpha regulates virulence but is not essential for mating.