Literature DB >> 3519465

Synergistic activity of rabbit granulocyte peptides against Candida albicans.

R I Lehrer, D Szklarek, T Ganz, M E Selsted.   

Abstract

Rabbit granulocytes contain six antimicrobial peptides that are structurally homologous to the human neutrophil "defensins." NP-5, a rabbit defensin, lacks significant activity against Candida albicans. Nevertheless, its addition to submicromolar concentrations of rabbit NP-1, NP-2, or NP-3a potentiates their candidacidal effect. Thus, granulocyte defensins can act synergistically against potential pathogens.

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Year:  1986        PMID： 3519465      PMCID： PMC260946          DOI： 10.1128/iai.52.3.902-904.1986

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  8 in total

1.  Isolation of polymorphonuclear leukocyte granules from rabbit bone marrow.

Authors:  H I Zeya; J K Spitznagel
Journal:  Lab Invest       Date:  1971-03       Impact factor: 5.662

2.  Arginine-rich proteins of polymorphonuclear leukocyte lysosomes. Antimicrobial specificity and biochemical heterogeneity.

Authors:  H I Zeya; J K Spitznagel
Journal:  J Exp Med       Date:  1968-05-01       Impact factor: 14.307

3.  Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages.

Authors:  M E Selsted; D M Brown; R J DeLange; R I Lehrer
Journal:  J Biol Chem       Date:  1983-12-10       Impact factor: 5.157

4.  Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes.

Authors:  R I Lehrer; K Daher; T Ganz; M E Selsted
Journal:  J Virol       Date:  1985-05       Impact factor: 5.103

5.  Activity of rabbit leukocyte peptides against Candida albicans.

Authors:  M E Selsted; D Szklarek; T Ganz; R I Lehrer
Journal:  Infect Immun       Date:  1985-07       Impact factor: 3.441

6.  Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes.

Authors:  M E Selsted; D Szklarek; R I Lehrer
Journal:  Infect Immun       Date:  1984-07       Impact factor: 3.441

7.  Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils.

Authors:  M E Selsted; D M Brown; R J DeLange; S S Harwig; R I Lehrer
Journal:  J Biol Chem       Date:  1985-04-25       Impact factor: 5.157

8.  Defensins. Natural peptide antibiotics of human neutrophils.

Authors:  T Ganz; M E Selsted; D Szklarek; S S Harwig; K Daher; D F Bainton; R I Lehrer
Journal:  J Clin Invest       Date:  1985-10       Impact factor: 14.808
  8 in total
  10 in total

Review 1.  Host defense peptides in the oral cavity and the lung: similarities and differences.

Authors:  G Diamond; N Beckloff; L K Ryan
Journal:  J Dent Res       Date:  2008-10       Impact factor: 6.116

Review 2.  Antifungal peptides: novel therapeutic compounds against emerging pathogens.

Authors:  A J De Lucca; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

3.  Antimicrobial mechanisms against Acinetobacter calcoaceticus of rat polymorphonuclear leukocyte granule extract.

Authors:  M J Loeffelholz; M C Modrzakowski
Journal:  Infect Immun       Date:  1988-03       Impact factor: 3.441

4.  Induction of epithelial chloride secretion by channel-forming cryptdins 2 and 3.

Authors:  W I Lencer; G Cheung; G R Strohmeier; M G Currie; A J Ouellette; M E Selsted; J L Madara
Journal:  Proc Natl Acad Sci U S A       Date:  1997-08-05       Impact factor: 11.205

Review 5.  Immunological aspects of fungal pathogenesis.

Authors:  G S Deepe; W E Bullock
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1990-08       Impact factor: 3.267

6.  Early differential molecular response of a macrophage cell line to yeast and hyphal forms of Candida albicans.

Authors:  E Blasi; L Pitzurra; M Puliti; L Lanfrancone; F Bistoni
Journal:  Infect Immun       Date:  1992-03       Impact factor: 3.441

7.  Plasmid RP1-mediated susceptibility of Acinetobacter calcoaceticus to rat polymorphonuclear leukocyte granule contents.

Authors:  M J Loeffelholz; M C Modrzakowski
Journal:  Infect Immun       Date:  1986-12       Impact factor: 3.441

8.  Purification of equine neutrophil lysozyme and its antibacterial activity against gram-positive and gram-negative bacteria.

Authors:  A Pellegrini; S Waiblinger; R Von Fellenberg
Journal:  Vet Res Commun       Date:  1991       Impact factor: 2.459

9.  The use of antimicrobial peptides in ophthalmology: an experimental study in corneal preservation and the management of bacterial keratitis.

Authors:  Mark J Mannis
Journal:  Trans Am Ophthalmol Soc       Date:  2002

Review 10.  Antimicrobial peptides: natural effectors of the innate immune system.

Authors:  Katherine Radek; Richard Gallo
Journal:  Semin Immunopathol       Date:  2007-04       Impact factor: 11.759
  10 in total

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