Literature DB >> 3519138

Molecular cloning of the gene encoding rabbit tumor necrosis factor.

H Ito, T Shirai, S Yamamoto, M Akira, S Kawahara, C W Todd, R B Wallace.   

Abstract

A rabbit genomic DNA library was screened using a cloned cDNA encoding rabbit tumor necrosis factor (TNF) as a probe. The entire gene sequence appears to be contained within a 3.2-kb Eco RI fragment. Comparison of the nucleotide sequence of the gene with that of the cDNA showed that the gene consists of four exons. The nucleotide sequence of the rabbit TNF gene is very homologous to that of the human TNF gene. Southern hybridization of the genomic DNAs showed that there is likely only a single TNF gene in each of the rabbit and human genomes.

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Year:  1986        PMID： 3519138     DOI： 10.1089/dna.1986.5.157

Source DB:  PubMed          Journal:  DNA        ISSN： 0198-0238


  10 in total

1.  Sequence of the tumor necrosis factor/cachectin (TNF) gene from Peromyscus leucopus (family Cricetidae).

Authors:  M D Crew; M E Filipowsky
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

2.  Chromatin structure and DNase I hypersensitivity in the transcriptionally active and inactive porcine tumor necrosis factor gene locus.

Authors:  P Kuhnert; E Peterhans; U Pauli
Journal:  Nucleic Acids Res       Date:  1992-04-25       Impact factor: 16.971

Review 3.  Cachectin/tumor necrosis factor: an endogenous mediator of shock and inflammation.

Authors:  B Beutler; A Cerami
Journal:  Immunol Res       Date:  1986       Impact factor: 2.829

4.  Expression of recombinant feline tumor necrosis factor is toxic to Escherichia coli.

Authors:  C M Otto; F Niagro; X Su; C A Rawlings
Journal:  Clin Diagn Lab Immunol       Date:  1995-11

5.  The genes for tumor necrosis factor (TNF-alpha) and lymphotoxin (TNF-beta) are tandemly arranged on chromosome 17 of the mouse.

Authors:  S A Nedospasov; B Hirt; A N Shakhov; V N Dobrynin; E Kawashima; R S Accolla; C V Jongeneel
Journal:  Nucleic Acids Res       Date:  1986-10-10       Impact factor: 16.971

6.  Effects of hyperoxia on tumor necrosis factor alpha and Grobeta expression in newborn rabbit lungs.

Authors:  R Varughese; J L Nayak; M LoMonaco; M A O'Reilly; R M Ryan; C T D'Angio
Journal:  Lung       Date:  2003 Nov-Dec       Impact factor: 2.584

7.  Exacerbation of toxic effects by endotoxin contamination of recombinant human tumor necrosis factor.

Authors:  Y Ozaki; T Oyama; S Kume
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

Review 8.  Cachectin/tumor necrosis factor exerts endocrine, paracrine, and autocrine control of inflammatory responses.

Authors:  B Sherry; A Cerami
Journal:  J Cell Biol       Date:  1988-10       Impact factor: 10.539

9.  Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages.

Authors:  A N Shakhov; M A Collart; P Vassalli; S A Nedospasov; C V Jongeneel
Journal:  J Exp Med       Date:  1990-01-01       Impact factor: 14.307

10.  Cloning, expression and characterization of biologically active feline tumour necrosis factor-alpha.

Authors:  E Rimstad; G H Reubel; G A Dean; J Higgins; N C Pedersen
Journal:  Vet Immunol Immunopathol       Date:  1995-04       Impact factor: 2.046
  10 in total

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